Manitoba Neuroscience Network Seminar Series - DR. DEREK VAN DER KOOY
Friday, February 22nd, 2013 | 2:00
Location: Theatre B, Basic Sciences Bldg. Bannatyne Campus
Topic: Where Brains Come From
Dr. Derek van der Kooy is Professor - Department of Molecular Genetics,
University of Toronto For more information, please see attached notice.
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca <mailto:kjorund@sbrc.ca> OR kjorund(a)yahoo.ca
<mailto:kjorund@yahoo.ca>
Couple reminders.....
Manitoba Neuroscience Network Seminar Series - DR. DEREK VAN DER KOOY
Friday, February 22nd, 2013 | 2:00 noon
Location: Theatre B, Basic Sciences Bldg. Bannatyne Campus
Topic: Where Brains Come From
Dr. Derek van der Kooy is Professor - Department of Molecular Genetics,
University of Toronto
For more information, please see attached notice.
-------------------------------------------
Edge of Science and Medicine Seminar Series - DR. DETLEY BOISON
Monday, February 25, 2013 | 12:00 - 1:00 PM
Location: Theatre B, Basic Sciences Bldg. Bannatyne Campus
TOPIC: Therapeutic Epilepsy Research: Focus on Adenosine.
**A STUDENT LUNCH*** WILL Follow at 1:15-2:15 PM in Pharmacology and
Therapeutics Library, A229 Chown Building
(please RSVP to raquel.nowlin(a)med.umanitoba.ca ASAP)
Dr. Detlev Boison - Interim Dow Chair of Neurology & Director of
Neurobiology Research
Director of Basic and Translational Research, Legacy Research Institute
Adjunct Professor - Oregon Health & Science University, Portland, OR
For more information, please see attached notice.
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
/sent on behalf of Geoff Hicks.....
Dear Colleagues,
I want to bring your attention to a visiting professor seminar next week
by Dr Dan Goldowitz (poster attached).
Would be terrific if you could send the seminar notice out to your own
email list. I have taken the liberty to include the faculty's
neuroscience programs as "co-hosts," recognizing that his seminar may be
of high interest to your research groups.
Please also note, all trainees (and in particular those in your own
programs) are invited to join later in the afternoon for a Developmental
Biology class lecture on brain development and neuro-developmental
diseases. This will be followed by a robust open discussion and plenty
of time to interact with Dr Goldowitz.
Dan has quite a full day, but please let me know if you would like to
meet with him personally, and I'll be happy to make whatever
arrangements I can.
with best regards,
Geoff Hicks, PhD
Director, Regenerative Medicine
University of Manitoba
Office: 204-787-2133
Fax: 204-787-2190
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
please pass along to your neuroscience students....
Dear Neuroscience students,
You are invited to attend a student lunch following the Edge of Science
Seminar on Monday February 25, 2013.
The Lunch will be held in the Pharmacology and Therapeutics Library A229
Chown Building at 1:15 pm.
Please RSVP if you will be attending by Friday February 15, 2013.
Please note: If you are planning to attend the lunch ,you are also
required to attend the seminar.
Best Regards,
Raquel Nowlin
Department of Pharmacology & Therapeutics
Faculty of Medicine
University of Manitoba
A203-753 McDermot Avenue
Winnipeg MB R3T 0T6
Phone: 204-789-3520
Fax: 204-789-3932
Email: raquel.nowlin(a)med.umanitoba.ca
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
**Please note time/location change for this seminar.
Manitoba Neuroscience Network
Seminar Series
Friday, February 22nd, 2013 | 2:00 pm
Dr. Derek van der Kooy
Professor
Department of Molecular Genetics
University of Toronto
Topic: Where Brains Come From
Location: Theatre B
Derek van der Kooy served as Professor in the Department of Anatomy and Cell Biology at the University of Toronto from 1991 until 2002, when he became a Professor in the Department of Molecular Genetics. Derek received a M.Sc. in Psychology at the University of British Columbia, and a Ph.D in Anatomy, first at Erasmus University in the Netherlands, and finishing in the Department of Anatomy at the University of Toronto. Dr. van der Kooy gained postdoctoral research experience at Cambridge University in England and at the Salk Institute in California.
The van der Kooy lab works on various stem cell biology and developmental biology research projects; specifically, stem cells in organisms from Drosophila to humans. We produced the first report of stem cells in the adult mammalian eye, published in 2000 in Science. We also have isolated a rare stem cell from the adult mouse and human pancreas that can show extensive proliferation under defined conditions in vitro. Of interest to the lab is the lineage of neural stem cells from pluripotent embryonic stem cells, with relevance to the origin of the earliest neural stem cell in the developing embryo.
ABSTRACT: One of the few neurobiological facts not anticipated by Cajal is the existence of neural stem cells in the embryonic and adult mammalian brain that can produce new neurons in the adult brain (new neurons first shown by Altman). The earliest mammalian neural stem cells differentiate from pluripotent embryonic stem cells. These primitive neural stem cells emerge in response to LIF and have a wider non-neural phenotypic potential than later neural stem cells. By embryonic day 8.5 in mouse, true FGF2 dependent neural stem cells emerge and by embryonic day 14 they have given rise to copies of themselves and to EGF dependent neural stem cells. The separate FGF2 and EGF dependent neural stem cells increase greatly in numbers later in neurogenesis, but by E14 appear identical to adult neural stem cells. The adult mammalian neural stem cells are mostly quiescent, dividing asymmetrically only once every few weeks.
Mouse embryonic stem (ES) cells cultured in low cell density, completely defined media adopt a neural identity. Using a clonal colony-forming assay, we identify the novel primitive neural stem cell stage as a component of neural lineage specification (this cell is similar to the one we isolate from the early embryo), which is negatively regulated by TGFb-related signaling. These results are consistent with a default mechanism for neural fate specification. Primitive neural stem cells are formed directly from single ES cells in a LIF-dependent manner, express multiple neural precursor markers and give rise to neurons and glia. Moreover, in vivo mouse chimera experiments reveal that these primitive ES-derived neural stem cells have a broad range of neural and non-neural lineage potential. These results support a model whereby definitive neural stem cell formation is preceded by a primitive neural stem cell stage during neural lineage commitment. Most recently, we have found that the LIF-dependent, primitive neural stem cells persist in adult organisms and can repopulate a depleted definitive neural stem cell pool in the adult.
For more information, contact the MNN Office at
(T) 235.3939 or email: mnn(a)sbrc.ca
Presented in co-operation with University of Manitoba
Clinical Neuroscience Rounds
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
From: Krystyna Kruczek [mailto:KKruczek@exchange.hsc.mb.ca]
Sent: February 12, 2013 10:48 AM
To: Kelly Jorundson
Subject: FW: Neuroscience Seminar Series - Feb. 22nd
Hi Kelly,
I am sending out the notice for February 22nd Neuroscience Rounds as Marie is away. Can you email me the information I need on the Neuroscience Seminar Series for that day?
Thanks.
Krys Kruczek
Administrative Assistant to,
Neil Berrington, MMed, FRCS, FCS (SA)
Assistant Professor
Head - Section of Neurosurgery
Phone: 204-787-7261
Fax: 204-787-3851
Email: KKruczek(a)exchange.hsc.mb.ca
P Please consider the environment before printing this email
From: Marie Field
Sent: Wednesday, February 06, 2013 9:39 AM
To: Krystyna Kruczek
Subject: Neuroscience Seminar Series
Hi Krys,
I receive info re the Neuroscience Seminar Series from:
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
I appreciate you contacting her for the February 22nd info and for sending out the Neuroscience Rounds notice while I am away.
_______________________________
Marie Field
Education Coordinator
Dermatology, Infectious Diseases, Neurology
and Physician Assistant Program
Department of Internal Medicine
University of Manitoba
GF328, Health Sciences Centre
Tel: (204) 787-8624 l Fax: (204) 787-4528
mfield(a)hsc.mb.ca
This message is forwarded on behalf of
Alexandra Stewart
Executive Director, Neuroscience
The W. Garfield Weston Foundation
------------------------------------
I am writing as the Executive Director, Neuroscience of The W. Garfield
Weston Foundation.
The Foundation is a private Canadian family foundation where donations
are directed to qualified donees in the fields of education, land
conservation, science in Canada's North and through unsolicited Trustee
Initiated Grants.
Last year, the Foundation launched a pilot funding program for
neuroscience research within the Greater Toronto Area. I am excited to
let you know the Foundation is launching another pilot funding program
for neuroscience research this week open to institutions across Canada.
We wanted to ensure you and the researchers at the University of
Manitoba were aware of this opportunity.
The goal of this request for proposals (RFP) is to provide funding for
translational research or clinical trials that will have
transformational impact in neurodegenerative diseases of aging.
The Foundation will commit up to $4 million to this program. Grants will
be for up to $500,000 per year for up to three years to a maximum of
$1.5 million per project.
Application requires a one to two page Letter of Intent due Monday,
March 25th, 2013. High potential applicants will be invited to submit a
short proposal, and grantees will be announced in the summer.
Details are attached and are also at
www.westonfoundation.org/pages/neuroscience.aspx<http://www.westonfoundation.org/pages/neuroscience.aspx>. Please let me know if a follow up
phone call would be helpful.
Questions about the RFP are also welcome at
info(a)westonneuroscience.ca<mailto:info@westonneuroscience.ca> or 416
935-4056.
Best wishes,
Alex
Alexandra Stewart
Executive Director, Neuroscience
The W. Garfield Weston Foundation
22 St. Clair Avenue East, Suite 2001
Toronto, ON M4T 2S3
alexandra.stewart(a)weston.ca<mailto:alexandra.stewart@weston.ca>
w: 416 922-1383 x 5764
f: 416 967-7949
<<Transformational RFP on Neurodegenerative Diseases of Aging.docx>>
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