Everyone is invited....
Seminar Series
Dr. Julia Rempel
Director, Liver Research Program
Assistant Professor, Dept Medicine/Immunology
University of Manitoba
"Hepatitis C virus and interferon treatment induced neuropsychiatric
disorders"
Friday, November 04
12:00 - 13:00
Pharmacology Library - Room A229 Chown Building **
**Video-linked to St. Boniface Research Centre Room R1002
Bio:
Dr. Julia Rempel received her PhD at The University of Manitoba in the
Department of Immunology in 1999 (Kent HayGlass supervisor). She did
her post-doctoral fellowship at the Scripps Research Institute, La
Jolla, CA, examining how viruses can cause disease through activating
deleterious pro-inflammatory immune responses in mouse models of
encephalitis. During this time, reports emerged suggesting that despite
a high burden of infectious disease within Aboriginal peoples,
Aboriginal ancestry allowed for more effective clearance of hepatitis C
virus infection. Intrigued, she returned to Manitoba in 2002 as a
member of the Section of Hepatology to study the interaction of
Aboriginal immunity and hepatitis C infection. Her laboratory (dubbed
the OOH-QUIN Immunology Laboratory, OOH-QUIN means liver in Cree and
Oji-cree) has been/is at the forefront in unveiling how immune genetics
and function influences disease outcomes in Aboriginal populations. She
has received national grants from CIHR and the Canadian Liver
Foundation, as well as local and pharmaceutical funding. The trainees
within her laboratory have also received numerous awards and
fellowships. In addition to scientific publications, she has made
extensive contributions to knowledge translation within the Aboriginal
community, including the production of a research video in Oji-cree.
Abstract of Research Interests:
The cornerstones of Dr. Rempel's research program are innate immunity,
liver disease, and Aboriginal health. The primary focus of her
laboratory has been exploring immune processes in the enhanced ability
of Aboriginal people's to spontaneously clear hepatitis C virus relative
to other peoples. With a combination of genetic and cell behavior
assays, her research team found that immune cells from Aboriginal
peoples have a greater genetic tendency to pro-inflammatory immunity and
a reduced susceptibility to hepatitis C virus protein deregulation
relative to Caucasian population controls. These ongoing studies
involve Aboriginal communities, as well as partners from the University
of Manitoba, the National Microbiology Laboratory (NML) and inner city
clinics. Clinical studies in collaboration with the Section of
Hepatology and Viral Hepatitis Investigation Unit continue to evaluate
immune responses of Aboriginal and Caucasian patients undergoing
treatment for chronic hepatitis C infection. As part of these studies,
they are considering the potential of baseline immunity to predict
therapeutic clearance and neuropsychiatric side effects. More recently,
her team has been concerned with the negative consequences of a highly
pro-inflammatory immune environment within the Aboriginal population.
To this end, they are working with the Pediatric Diabetes Unit to
examine immunopathogenesis in type 2 diabetes of Aboriginal youth.
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
T: 204.235.3939 f: 204.237.4092
Email: wcsn(a)sbrc.ca
Website: sfn-manitoba.ca
Winnipeg Chapter Society for Neuroscience presents2012 Schedule
(Presented in co-operation with University of Manitoba Clinical
Neuroscience Rounds )
Manitoba Neuroscience Network Seminar Series - 2011/2012
**All seminars are held last Friday of each month 9:00 - 10:00 am
Rm PX236/238 Psych Health Bldg, Bannatyne Campus**
------------------------------------------------------------------------
-----------------------
Date Speaker
September 30, 2011
Dr. Brent Fedirchuk
Associate Professor, Department of Physiology
University of Manitoba
October 28, 2011
Dr. Mark Fry
Assistant Professor, Department of Biological Sciences
University of Manitoba
November 25, 2011
Dr. Larry Jordon
Professor, Department of Physiology
University of Manitoba
January 27, 2012
Dr. Xin-Min Li
Medical Director, IMG Program
Professor, Department of Psychiatry
University of Manitoba
February 24, 2012
Dr. Sari Hannila
Assistant Professor, Department of Human Anatomy & Cell Sciences,
University of Manitoba
March 30, 2012
Dr. Gordon Glazner
Associate Professor - Department of Pharmacology &
Therapeutics, University of Manitoba
ril 27, 2012
OPEN
May 25, 2012
Dr. Jiming Kong
Associate Professor - Department of Human Anatomy & Cell Sciences,
University of Manitoba
For more information contact the MNN office
mnn(a)sbrc.ca or (T) 235.3939
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
T: 204.235.3939 f: 204.237.4092
Email: wcsn(a)sbrc.ca
Website: sfn-manitoba.ca
Manitoba Neuroscience Network Seminar: DR. MARK FRY
Friday, October 28th, 2011 | 9:00 - 10:00am
DR. MARK FRY
Assistant Professor, Department of Biological Sciences
University of Manitoba
Topic: Roles of the subfornical organ in regulating energy balance.
Location: PX236/238 PsychHealth, Bannatyne Campus
The main focus of the research carried out in the lab is to understand
the physiology of neurons that regulate homeostasis. In particular, the
lab is interested in understanding regulation of electrical activity in
neurons that control food intake and other aspects of energy
homeostasis. Neurons of the sensory circumventricular organs (CVOs) are
thought to be especially important for regulation of homeostasis because
these neurons are not protected by the blood-brain barrier, and are able
to sense hunger-stimulating and satiety (hunger-ending) hormones
circulating in the bloodstream.
A second focus of research aims to understand roles of different ion
channels in the regulation of electrical excitability of neurons. Ion
channels are proteins in neuronal cell membranes that undergo
conformational changes to form a pore that allows charged ions such as
Na+, Ca++, K+ and Cl- to flow into or out of the cell. These "ionic
currents" are the basis of the neuronal action potential and neuronal
communication within the CNS. There is a large diversity of ion
channels: dozens of ion channel gene families have been described, and
many families have numerous isoforms. These isoforms exhibit only subtle
structural differences, but often exhibit dramatic functional
differences. Populations of neurons may express vastly different
complements of these isoforms and the relationship between ion channel
isoform expression and the patterns of neuronal electrical activity is
only beginning to be understood. Acutely modulating neuronal ion channel
properties by activating intracellular signalling pathways or by
changing expression patterns of ion channels by disease or other
stimulus can result in dramatic changes in neuronal function.
For more information, contact the MNN Office at
(T) 235.3939 or email: mnn(a)sbrc.ca
Presented in co-operation with University of Manitoba
Clinical Neuroscience Rounds
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
T: 204.235.3939 f: 204.237.4092
Email: wcsn(a)sbrc.ca
Website: sfn-manitoba.ca
Everyone is invited.....
(Hosted by the Division of Neurodegenerative Disorders
<http://www.sbrc.ca/content/blogcategory/38/51/> , St. Boniface Hospital
Research)
Dr. Jaideep Bains
<http://www.hbi.ucalgary.ca/members/bains> Professor, Hotchkiss Brain
Institute &
Dept Physiology & Pharmacology,
University of Calgary
Topic: Synapses and the stress response.
Friday, Oct. 7th, 2011
12:00 NOON
Theatre "C" BMSB Bannatyne Campus
Bio
- Professor, Hotchkiss Brain Institute and Department of Physiology &
Pharmacology, University of Calgary
- Member of CIHR Institute of Neuroscience Mental Health and Addiction
Institute Advisory Board
- PhD Queen's University 1997
- Human Frontiers and Epilepsy Foundation of America Postdoctoral
- Fellow, University of Colorado Health Sciences Center, Denver, CO
1997-2001
Research Interests: The goal of my lab is to understand how
physiological and behavioural challenges lead to long-term changes in
neural circuitry. We focus on neurons that coordinate an organism's
response to stress, with a particular interest in clarifying how the
molecules released at the onset of a stressful stimulus leave a lasting
imprint on how 'stress-relevant' circuitry functions. Within this
context, we conduct experiments that will allow us to understand the
fundamental rules that govern cell to cell communication within the
hypothalamus and elucidate the molecular machinery that contributes to
changes in synaptic function which, in turn, may be critical for
changing network output.
everyone is invited....
Division of Neurodegenerative Disorders Visiting Speaker:
Dr. Jaideep Bains
Dr. Jaideep Bains
Professor, Hotchkiss Brain Institute &
Dept Physiology & Pharmacology,
University of Calgary
Friday, Oct. 7th, 2011
12:00 NOON
Theatre "C" BMSB Bannatyne Campus
Topic: Synapses and the stress response.
pic:
Bio: PhD Queen's University 1997
Human Frontiers and Epilepsy Foundation of America Postdoctoral
Fellow, University of Colorado Health Sciences Center, Denver, CO
1997-2001
Currently: Professor, Hotchkiss Brain Institute and Department of
Physiology & Pharmacology, University of Calgary
Member of CIHR Institute of Neuroscience Mental Health and Addiction
Institute Advisory Board
or more information
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
T: 204.235.3939 f: 204.237.4092
Email: wcsn(a)sbrc.ca
Website: sfn-manitoba.ca