Visiting Speaker & Seminar Series
Friday, November 25th, 2016
9:00 - 10:00 a.m.
PX236/238 PscyHealth Bldg., Bannatyne Campus
DR. TABREZ SIDDIQUI
Assistant Professor of Physiology and Pathophysiology,
College of Medicine, Faculty of Health Sciences, University of Manitoba.
Principal Investigator, Neuroscience Research Program,
Kleysen Institute for Advanced Medicine, Health Sciences Centre
TOPIC: "Molecular mechanisms of neuronal synapse development"
The Siddiqui laboratory is interested in learning how nerve cell connections
known as "synapses" form and function in the developing and adult brain.
Synapses are the fundamental units for information processing in the brain.
Evidence from genetic studies, animal models and post-mortem human tissue
indicate impairment of synapse development and synaptic dysfunction in
neuropsychiatric disorders such as autism and schizophrenia.
Synapses undergo morphological and functional changes in response to neural
activity, a phenomenon known as plasticity. These experience-dependent
plastic changes at synapses are critical for cognitive processes including
learning and memory. Our work focusses on the roles of cell adhesion and
scaffolding molecules in the development, maintenance and plasticity of
synapses and how these processes can be regulated in health and disease. We
are particularly interested in understanding how specific neural circuits
essential for learning and memory form and function in the brain.
To address our questions, we combine multiple interdisciplinary methods
ranging from biochemical and biophysical approaches to cellular, molecular
and genetic studies, particularly regional and temporal manipulation of
synaptic genes in mice brains. We are also developing our capabilities in
behavioral studies in mouse models of autism and schizophrenia.
http://umanitoba.ca/faculties/health_sciences/medicine/units/physiology/cont
acts/8986.html
Learning Objective: To understand the molecular mechanisms regulating the
development of synaptic circuitry in the mammalian brain
/sent on behalf of
Dr. Eftekhar Eftekharpour
Coordinator - MNN Visiting Speaker & Seminar Series Program
eftekhar.eftekharpour(a)umanitoba.ca
<mailto:eftekhar.eftekharpour@umanitoba.ca>
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For anyone attending the SFN meeting in San Diego, there will be a Winnipeg dinner hosted by the Manitoba Neuroscience Network on NOVEMBER 14 at 7:00 pm. This was the time that worked best for a large majority of poll respondants; apologies to those who cannot make it then. The dinner will be at Mariscos El Pulpo. This is Mexican/seafood restaurant but those not excited by seafood can find other options as well. The address is 415 Market St, San Diego CA 92101 (Between 4th and 5th Avenues on Market street). More information at elpulposd.com<http://www.elpulposd.com/>. To be clear, we will all have to pay for our own food and drinks.
Please attend if you can. We'd love to see you there!
Chris Anderson
MNN President
