Dear All,
As you may know, The Manitoba Neuroscience Network will be hosting Dr.
Derek van der Kooy on Feb 22, 2013. He is currently a Professor at the
Department of Medical Genetics. Dr. van der Kooy is one of the pioneers
of the field of adult stem cells. His publications in the field of
Neural stem cells, Retinal stem cells and pancreatic stem cells are
published in top journals such as Cell, Science, Nature,
Neuron,Development and J Neuroscience are highly cited. Dr. van der
Kooy is also a great speaker and I will hope that you will try to attend
his lecture on Feb 22, at noon, Room 626 in Regenerative Medicine.
I am trying to schedule his short day visit on Feb 22nd and therefore I
am asking those interested in meeting him to contact me at
eftekhar(a)cc.umanitoba.ca. We may have to arrange for group meetings if
individual meetings are not possible. The meetings will be planned in a
meting room in Regen Med for the sake of time.
Thank you for your time,
Regards
--
Edge of Science and Medicine Seminar Series | Dr. Paul Fernyhough
Monday, February 04, 2013
12:00 - 1:00 PM
Theatre B - Basic Medical Sciences
Dr. Paul Fernyhough
Professor - Departments of Pharmacology and Therapeutics & Physiology
University of Manitoba
Director, Division of Neurodegenerative Disorders -St. Boniface Research
Centre
TOPIC: Drug discovery for neurological disease
-------------------------------------------------------------
Manitoba Neuroscience Network Seminar Series | Dr. Derek van der Kooy
Friday, February 22nd, 2013 | 12:00 noon
Location: Regenerative Medicine Lecture Theatre (626 BMSB)
Dr. Derek van der Kooy
Professor, Department of Molecular Genetics
University of Toronto
Topic: Where Brains Come From
For more information, contact the MNN Office at
(T) 235.3939 or email: mnn(a)sbrc.ca
Presented in co-operation with University of Manitoba Clinical
Neuroscience Rounds
-------------------------------------------------------------
Edge of Science and Medicine Seminar Series | Dr. Detlev Boison
Monday, February 25, 2013
Theatre B Basic Medical Sciences
12:00 - 1:00 PM
Dr. Detlev Boison
Interim Dow Chair of Neurology & Director of Neurobiology Research
Director of Basic and Translational Research, Legacy Research Institute
Adjunct Professor - Oregon Health & Science University, Portland, OR
TOPIC: Therapeutic Epilepsy Research: Focus on Adenosine.
-------------------------------------------------------------
Manitoba Neuroscience Network Seminar | Dr. X.-M. Li
Date: Friday, March 22, 2013
Time: 9:00 am - 10:00 am
Location: PZ236/238 PsychHealth Centre, Bannatyne Campus
Dr. Xin-Min Li
Professor, Department of Psychiatry
University of Manitoba
Topic: Depression: from clinical guidelines to neurobiology.
-------------------------------------------------------------
Message from the Winnipeg Chapter of the Society for Neuroscience
Please reserve MONDAY JUNE 10, 2013 for the 4th annual meeting of the
Manitoba Neuroscience Network.
The theme for 2013 will be "Neurodegeneration" and the meeting will be
held jointly with the Manitoba-Ontario endMS Regional Research and
Training Centre.
The format will be similar to previous meetings, featuring:
* Visiting expert speakers
* Speakers showcasing local research
* Networking opportunities
* Poster session with trainee awards
The official meeting and website announcement will follow early in 2013,
with a MAY abstract deadline.
Please plan on attending and thank you for making these meetings
successful.
Chris Anderson, Conference Chair
Gilbert Kirouac, Program Committee Chair
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
Website: www.sfn-manitoba.ca
Manitoba Neuroscience Network
Seminar Series
Friday, February 22nd, 2013 | 12:00 noon
Dr. Derek van der Kooy
Professor
Department of Molecular Genetics
University of Toronto
Topic: Where Brains Come From
Location: Regenerative Medicine Lecture Theatre (626 BMSB)
Derek van der Kooy served as Professor in the Department of Anatomy and
Cell Biology at the University of Toronto from 1991 until 2002, when he
became a Professor in the Department of Molecular Genetics. Derek
received a M.Sc. in Psychology at the University of British Columbia,
and a Ph.D in Anatomy, first at Erasmus University in the Netherlands,
and finishing in the Department of Anatomy at the University of Toronto.
Dr. van der Kooy gained postdoctoral research experience at Cambridge
University in England and at the Salk Institute in California.
The van der Kooy lab works on various stem cell biology and
developmental biology research projects; specifically, stem cells in
organisms from Drosophila to humans. We produced the first report of
stem cells in the adult mammalian eye, published in 2000 in Science. We
also have isolated a rare stem cell from the adult mouse and human
pancreas that can show extensive proliferation under defined condi-tions
in vitro. Of interest to the lab is the lineage of neural stem cells
from pluripotent embryonic stem cells, with relevance to the origin of
the earliest neural stem cell in the developing embryo.
ABSTRACT: One of the few neurobiological facts not anticipated by Cajal
is the existence of neural stem cells in the embryonic and adult
mammalian brain that can produce new neurons in the adult brain (new
neurons first shown by Altman). The earliest mammalian neural stem cells
differentiate from pluripotent embryonic stem cells. These primitive
neural stem cells emerge in response to LIF and have a wider non-neural
phenotypic potential than later neural stem cells. By embryonic day 8.5
in mouse, true FGF2 dependent neural stem cells emerge and by embryonic
day 14 they have given rise to copies of themselves and to EGF dependent
neural stem cells. The separate FGF2 and EGF dependent neural stem cells
increase greatly in numbers later in neurogenesis, but by E14 appear
identical to adult neural stem cells. The adult mammalian neural stem
cells are mostly quiescent, dividing asymmetrically only once every few
weeks.
Mouse embryonic stem (ES) cells cultured in low cell density, completely
defined media adopt a neural identity. Using a clonal colony-forming
assay, we identify the novel primitive neural stem cell stage as a
component of neural lineage specification (this cell is similar to the
one we isolate from the early embryo), which is negatively regulated by
TGFb-related signaling. These results are consistent with a default
mechanism for neural fate specification. Primitive neural stem cells are
formed directly from single ES cells in a LIF-dependent manner, express
multiple neural precursor markers and give rise to neurons and glia.
Moreover, in vivo mouse chimera experiments reveal that these primitive
ES-derived neural stem cells have a broad range of neural and non-neural
lineage potential. These results support a model whereby definitive
neural stem cell formation is preceded by a primitive neural stem cell
stage during neural lineage commitment. Most recently, we have found
that the LIF-dependent, primitive neural stem cells persist in adult
organisms and can repopulate a depleted definitive neural stem cell pool
in the adult.
For more information, contact the MNN Office at
(T) 235.3939 or email: mnn(a)sbrc.ca <mailto:mnn@sbrc.ca>
Presented in co-operation with University of Manitoba
Clinical Neuroscience Rounds
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
Website: www.sfn-manitoba.ca
You are receiving this message either because you are a Winnipeg Chapter
Society for Neuroscience (WCSN) member due for 2013 renewal or because
you are a person we think may benefit from membership in your local
Chapter of the international Society for Neuroscience. The WCSN
organizes and promotes events in Manitoba designed to fuel excellence in
Neuroscience research, education and outreach. We are the driving force
behind the Manitoba Neuroscience Network annual meetings, seminar series
and visiting speaker program. We also organize Brain Awareness Week
activities and contribute to the development of local neuroscientists by
awarding prizes for excellence at the Manitoba Science Schools
Symposium. Please support initiatives such as these and help us build a
strong and vibrant neuroscience community in Manitoba by clicking on
this link www.sfn-manitoba.ca/application
<http://www.sfn-manitoba.ca/application> to pay your dues by credit
card, University of Manitoba FOAP, or cheque. A receipt will be
issued by e-mail.
2013 MEMBERSHIP FEE SCHEDULE
Students
$ 15
Postdocs, Residents, Associates, Technicians
$ 30
Faculty, Professionals
$ 60
*All-inclusive Lab rate
$ 100
*PI and names and affiliations of each individual lab member
must be provided.
If you have any questions about our vision, please contact the Chapter
president at canderson(a)sbrc.ca <mailto:canderson@sbrc.ca> .
Sincerely,
Chris Anderson, PhD
President - Winnipeg Chapter Society for Neuroscience
Associate Professor, University of Manitoba
Winnipeg Chapter Society for Neuroscience
General Office:
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939 Fax: 204.237.4092
Email: wcsn(a)sbrc.ca <mailto:wcsn@sbrc.ca> <mailto:wcsn@sbrc.ca
<mailto:wcsn@sbrc.ca> >
Website: www.sfn-manitoba.ca <http://www.sfn-manitoba.ca>
Manitoba Neuroscience Network Seminar Series:
Friday, January 25th, 2013 | 9:00 am
Dr. Tamra Werbowetski-Ogilvie
Canada Research Chair in Neuro-oncology & Human Stem CellsAssistant Professor, Regenerative Medicine ProgramDepartment of Biochemistry & Medical Genetics and Physiology
University of Manitoba
Topic: Deconstructing medulloblastoma heterogeneity: targeting a spectrum of phenotypes.
Location: PX236/238 PsychHealth Bldg.
SHORT BIOSKETCH
* Assistant Professor | Regenerative Medicine Program, Department of Biochemistry & Medical Genetics & Physiology, University of Manitoba
* Honours Bachelor of Science in Biology, University of Western Ontario, London, ON
* PhD Neuroscience (Department of Neurology and Neurosurgery) Montreal Neurological Institute, McGill University, Montreal, QC.
Positions and Employment:
- August 2005-October 2010 PDF, McMaster Stem Cell and Cancer Research Institute, McMaster Univ.
- November 2010-present Assistant Professor, Regenerative Medicine Program, Department of Biochemistry & Medical Genetics And Physiology, University of Manitoba, Winnipeg, Manitoba, Canada
Selected Peer Reviewed Publications (Selected from 18 peer-reviewed publications)
1. Werbowetski T, Bjerkvig R, Del Maestro R. 2004. Evidence for a secreted chemorepellent that directs glioma cell invasion. Journal of Neurobiology 60(1): 71-88.
2. Werbowetski-Ogilvie TE, Seyed Sadr M, Jabado N, Angers-Loustau A, Agar NY, Wu J, Bjerkvig R, Antel J, Faury D, Rao Y, Del Maestro RF. 2006. Inhibition of medulloblastoma cell invasion by Slit. Oncogene 25(37) 5103-5112.
3. Werbowetski-Ogilvie TE*, Agar NY*, Waldkircher de Oliveira RM, Faury D, Antel JP, Jabado N, Del Maestro RF. 2006. Isolation of a natural inhibitor of human malignant glial cell invasion: inter alpha trypsin inhibitor heavy chain 2. *These authors contributed equally to this work. Cancer Research 66(3) 1464-1472.
4. Cerdan C, Bendall SC, Wang L, Stewart M, Werbowetski T, Bhatia M. 2006. Complement targeting of nonhuman sialic acid does not mediate cell death of human ESCs. Nature Medicine 12(10) 1113-1114.
5. Bendall SC, Stewart MH, Menendez P, George D, Vijayaragavan K, Werbowetski-Ogilvie T, Ramos-Mejia V, Rouleau A, Yang J, Bossé M, Lajoie G, Bhatia M. 2007. IGF and FGF cooperatively establish the regulatory stem niche of pluripotent human cells. Nature. 448:1015-1021.
6. Werbowetski-Ogilvie TE, Bossé M, Stewart M, Schnerch A, Ramos-Mejia R, Rouleau A, Wynder T, Smith MJ, Dingwall S, Carter T, Williams C, Harris C, Dolling J, Wynder C, Boreham D. Bhatia M. 2009. Characterization of human embryonic stem cells with features of neoplastic progression. Nature Biotechnology. 27:91-97
7. Ji JF*, Werbowetski-Ogilvie TE*, Zhong B, Hong SH, Bhatia M. 2009. Pluripotent transcription factors possess distinct roles in normal versus transformed human stem cells. * These authors contributed equally to this work. PLoS ONE. 4:11
8. Werbowetski-Ogilvie TE, Schnerch A, Rampalli S, Lee JB, Levadoux-Martin M, Mills CE, Bhatia M. 2011. Evidence for the transmission of neoplastic properties from transformed to normal human stem cells. Oncogene. 30(46): 4632-44
9. Werbowetski-Ogilvie TE*, Coudière Morrison L, Fiebig-Comyn A, Bhatia M*. 2012. In vivo generation of neural tumors from neoplastic pluripotent stem cells models early human pediatric brain tumor formation. Stem Cells. 30(3): 392-404. * Denotes co-corresponding authorship.
10. Coudière Morrison *, McClelland R *, Aiken C, Bridges M, Wang X, Del Bigio MR, Taylor MD, Werbowetski-Ogilvie TE. 2012. Deconstruction of medulloblastoma cellular heterogeneity reveals differences between the most highly invasive and self-renewing phenotypes. Under Review, Neoplasia.
For more information, contact the MNN Office at
(T) 235.3939 or email: mnn(a)sbrc.ca
Presented in co-operation with University of Manitoba
Clinical Neuroscience Rounds
An initiative of:
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
Everyone is invited....
Edge of Science and Medicine Seminar Series
Monday, February 04, 2013
12:00 - 1:00 PM
Theatre B - Basic Medical Sciences
Dr. Paul Fernyhough
Professor - Departments of Pharmacology and Therapeutics & Physiology
University of Manitoba
Director, Division of Neurodegenerative Disorders -St. Boniface Research
Centre
TOPIC: Drug discovery for neurological disease
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
everyone is invited!
Edge of Science and Medicine Seminar Series
Monday, February 04, 2013
12:00 - 1:00 PM
Theatre B - Basic Medical Sciences
Dr. Paul Fernyhough <http://www.sbrc.ca/dnd/faculty/dr-paul-fernyhough/>
Professor - Departments of Pharmacology and Therapeutics & Physiology
University of Manitoba
Director, Division of Neurodegenerative Disorders -St. Boniface Research
Centre
TOPIC: Drug discovery for neurological disease
For more information contact:
Karen Donald
204.789.3553
Karen.Donald(a)med.umanitoba.ca
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
Reminder:
Manitoba Neuroscience Network
Seminar Series
Friday, January 18th, 2013 | 12:00 noon
Dr. Samuel David
Professor - Department of Neurology & Neurosur-gery, Centre for Research
in Neuroscience,
Research Institute of the McGill University Health Centre
Topic: Targeting inflammation in spinal cord injury
Location: Theatre B, Bannatyne Campus
Short Biosketch: Dr. Sam David is a Professor in the Department of
Neurology and Neurosurgery, at the Centre for Research in Neuroscience,
The Research Institute of the McGill University Health Center in
Montreal. He obtained his PhD degree in 1979 from the University of
Manitoba, and did postdoctoral work at McGill University and University
College London, UK. His research focuses on molecular mechanisms of
inflammation after spinal cord and peripheral nerve injury, CNS
autoimmune disease, and the molecular control of iron homeostasis in the
CNS and its dysregulation in CNS pathologies. He has published in top
tier journals such as Science, PNAS, Neuron, Nature Immunology, Nature
Reviews Neuroscience, Brain, and Journal of Neuroscience. He is Director
of the CIHR Training Program in Neuroinflammation, which includes 16
laboratories at three Montreal area Universities. He is the current
President of the Canadian Association of Neuroscience, member of the
Medical Advisory Committee of the MS Society of Canada, member of the
Scientific Advisory Board of Wings for Life Spinal Cord Research
Foundation, and other organizations.
For more information, contact the MNN Office at
(T) 235.3939 or email: mnn(a)sbrc.ca
Presented in co-operation with University of Manitoba
Clinical Neuroscience Rounds
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
Please circulate notice to your students.....
Attention Graduate Students:
Graduate Student Luncheon with MNN Speaker: Dr. Samuel David
What: Lunch with Dr. Samuel David and students
When: Friday, January 18, 1:00 pm
Where: Physiology Library Room 431, BMSB, Bannatyne Campus
On January 18th the Winnipeg Chapter for Neuroscience and the Manitoba
Neuroscience Network will be hosting Dr. Samuel David, President of the
Canadian Association for Neuroscience. For more information follow the
link: http://www.sfn-manitoba.ca/news/?id+20120912wcsn5.txt
Following the 12:00 pm seminar, graduate students will have the
opportunity to meet Dr. David in an informal lunch. Please circulate
this e-mail; all students are welcome. Also, please confirm your
attendance by January 13, to the address esteli(a)scrc.umanitoba.ca and
indicate whether your have any dietary restrictions.
Thank you,
sent on behalf of/
Esteli Vasquez
PhD Student
Spinal Cord Research Centre
Department of Physiology, University of Manitoba
745 Bannatyne Avenue
Winnipeg, Manitoba R3E 0J9
Phone: (204) 789-3274, Fax: (204) 789-3930
E-Mail: esteli(a)scrc.umanitoba.ca
everyone is invited!!
Manitoba Neuroscience Network
Seminar Series
Friday, January 18th, 2013 | 12:00 noon
Dr. Samuel David
Professor - Department of Neurology & Neurosur-gery, Centre for Research
in Neuroscience,
Research Institute of the McGill University Health Centre
Topic: Targeting inflammation in spinal cord injury
Location: Theatre B, Bannatyne Campus
Short Biosketch: Dr. Sam David is a Professor in the Department of
Neurology and Neurosurgery, at the Centre for Research in Neuroscience,
The Research Institute of the McGill University Health Center in
Montreal. He obtained his PhD degree in 1979 from the University of
Manitoba, and did postdoctoral work at McGill University and University
College London, UK. His research focuses on molecular mechanisms of
inflammation after spinal cord and peripheral nerve injury, CNS
autoimmune disease, and the molecular control of iron homeostasis in the
CNS and its dysregulation in CNS pathologies. He has published in top
tier journals such as Science, PNAS, Neuron, Nature Immunology, Nature
Reviews Neuroscience, Brain, and Journal of Neuroscience. He is Director
of the CIHR Training Program in Neuroinflammation, which includes 16
laboratories at three Montreal area Universities. He is the current
President of the Canadian Association of Neuroscience, member of the
Medical Advisory Committee of the MS Society of Canada, member of the
Scientific Advisory Board of Wings for Life Spinal Cord Research
Foundation, and other organizations.
For more information, contact the MNN Office at
(T) 235.3939 or email: mnn(a)sbrc.ca
Presented in co-operation with University of Manitoba
Clinical Neuroscience Rounds
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca