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To all,
Brain Canada is pleased to launch a new funding program in partnership with CQDM that will provide $10 million to support the development of innovative tools, technologies and platforms to accelerate the discovery of new, safe and effective drugs for disorders of the brain and nervous system.
This new program intends to bridge the gap in neuroscience by supporting innovative translational research with tangible results that impact the drug discovery process, with the ultimate goal to prevent, treat or cure neurological or mental health disorders for the benefit of patients and their families. The program aims to foster multidisciplinary research collaborations linking Quebec and other Canadian researchers, as well as the academic and Small and Medium Enterprises (SMEs).
The deadline to submit a Letter of Intent (LOI) is August 20th, 2014.
For more information, please visit Brain Canada's website:
http://braincanada.ca/en/Focus_on_Brain<http://braincanada.us3.list-manage1.com/track/click?u=eae5bfcdc68eabe292cb4…>
We thank you in advance for disseminating in your networks.
The Brain Canada Team
The Weston Brain Institute has new funding opportunities available. Please have a close look:
All funding programs support translational research to accelerate the development of therapeutics for neurodegenerative diseases of aging. As the Institute defines it, these diseases include:
* Alzheimer's disease
* Amyotrophic lateral sclerosis (ALS)
* Dementia with Lewy bodies
* Frontotemporal dementia
* Mild cognitive impairment as prodromal to one of the other listed diseases
* Multiple system atrophy
* Parkinson's disease
* Progressive supranuclear palsy
Submissions open: approximately August 2014
Seed funding (up to $150,000 for up to 18 months) for high-risk, high-reward, totally novel ideas.
One Time Program:
2014 Targeted Diseases: FTD and PSP*
Application deadline: Friday, June 6th, 2014
The Institute will commit up to $1.35 million to this program. Per project, funding can range from $50,000 to $150,000 per year over 1 to 3 years to a maximum of $450,000.
The Institute will commit up to $1.35 million to this program. Funding can range from $50,000 to $150,000 per year over 1 to 3 years to a maximum of $450,000.
research in frontotemporal dementia (FTD) and/or progressive supranuclear palsy (PSP).
Research in other overlapping tauopathies, such as corticobasal degeneration, is not supported at this time.
/sent on behalf of
Chris M. Anderson, PhD
President - Winnipeg Chapter Society for Neuroscience
Associate Professor and Director, Neuroscience Research Program
Kleysen Institute for Advanced Medicine
Health Sciences Centre and University of Manitoba
T: 204-318-2565
E: chris.anderson(a)med.umanitoba.ca<mailto:chris.anderson@med.umanitoba.ca>
Kelly Jorundson
Executive Assistant
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939 Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR Kelly.jorundson(a)med.umanitoba.ca<mailto:Kelly.jorundson@med.umanitoba.ca>
Website: www.sfn-manitoba.ca<http://www.sfn-manitoba.ca>
Please Circulate!
Manitoba Neuroscience Network
Seminar Series
Friday, May 30, 2014 | 9:00 AM
Dr. Eftekhar Eftekharpour
Assistant Professor,
Regenerative Medicine Program
Spinal Cord Research Centre
Department of Physiology
University of Manitoba
Topic: Manipulation of Redox Regulation for Neurotrauma Repair.
Location: PX236/238 Psych Health Bldg.
Research in Neuroprotection: My laboratory is interested in
understanding the cellular and molecular events after Neurotrauma . Our
overall aim is to find clinically relevant
neuroprotective approaches to decrease the extent of cell death and to
enhance cell survival after injury/stroke. Increasing evidence indicate
that limiting the extent of cell death will result in improved tissue
repair and functional recovery for patients. Despite extensive research
in this
field, there is currently no effective treatment available. In our
laboratory, we focus on the oxidative stress as a major underlying
mechanism
in injury and stroke pathophysiology. We aim to:
1) use antioxidant therapy to enhance neural cell survival immediately
after injury.
2) enhance cell preservation and regeneration for enhancement of repair.
Short Biosketch: Eftekhar received his BSc and MSc from Tehran
University, Iran. He moved to Canada in 1996 to study Neuroscience at
the Department of
Anatomy and Cell Biology University of Saskatchewan. After graduating in
2001, he moved to Toronto Western Hospital Research Institute
for a postdoctoral training in Spinal Cord Injury in the Laboratory of
Dr. Michael Fehlings. His work focused on understanding the cellular
and molecular systems involved in spinal cord injury and repair with
special interests in stem cell therapy. His work has been published in
the
leading journals of the field including the Journal of Neuroscience.
After completion of post-doctoral training, he worked as a staff
scientist at
the University Health Network Spinal Cdrd Injury Group in Toronto until
2010, when he moved to the Spinal Cord Research Centre at the
University of Manitoba. Eftekhar has established his laboratory in 2012
and his research focuses on neuroprotection strategies for treatment
of neurotrauma.
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
Website: www.sfn-manitoba.ca
Please note that the talk originally scheduled for Friday May 30th at
9am has been cancelled. Apologies for inconvenience.
Regards,
Kelly
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
Website: www.sfn-manitoba.ca
BME Seminar
Speaker: Dr. Chris Ellis Ph.D.
Title: Microvasculature Regulation of Oxygen Supply: the most important
control system on planet Earth?
Time: 4:00-5:00 PM
Date: Thursday, May 29, 2014
Location: E2-330 Engineering Building, Fort Gary Campus
Some refreshment will be provided for after the seminar.
To see the list of next scheduled BME seminars, please seehere:
http://umanitoba.ca/biomedical_engineering/courses/bme_seminars.html
Abstract of the talk
Oxygen plays a critical role in almost every cell of the body, from
energy production in the mitochondria to generation of key signaling
molecules such as nitric oxide and carbon monoxide. To fulfill these
functions, O2 must diffuse from an O2 source (e.g. erythrocyte in a
capillary) through the cell (or cells) to the site where it will be used
(consumed). But diffusion into an O2 consuming tissue places a
biophysical limitation on the maximum cell size and the maximum distance
between O2 sources within an organ. Ninety five years ago Krogh was the
first to recognize that it was not adequate to simply deliver the
correct amount of O2 to an organ, the vasculature needed to match the
distribute the O2 supply to the O2 needs of the tissue to within a few
10's of micrometers of where it would be consumed. To meet this design
constraint Krogh proposed that capillary density was actively
controlled; as O2 consumption increased more capillaries would be
recruited to minimize diffusion distances. Despite the importance of
Krogh's insights, there was a fundamental flaw in his model of tissue
oxygenation and his concept of capillary recruitment has never been
proven. This talk will describe our current understanding of how the
microvasculature regulates the distribution of O2 supply within a
tissue. The situation is far more complex than controlling capillary
density due to a wide range of factors such as the unique fluid dynamic
properties of blood flow in the network of very small vessels that make
up the microvasculature (arterioles, capillaries and venules), the
complex three dimensional geometry of the microvasculature and
diffusional exchange of O2 among all levels of the microvasculature as
well as with the tissue. Our hypothesis is that the O2 supply to
individual capillary units (capillaries supplied by a single terminal
arteriole) is regulated by the hemoglobin O2 saturation dependent
release of ATP (adenosine triphosphate) from red blood cells in
capillaries and that receptors on the capillary endothelium detect the
ATP levels and signal upstream arterioles to dilate via conducted
hyperpolarization of endothelial membrane potential. To test the
hypothesis that individual capillary units can regulate their O2 supply,
we used a microfluidic device to perturb O2 levels in small groups of
capillaries at the surface of skeletal muscle in rat hindlimb and a dual
wavelength intravital video microscopy system for measuring red blood
cell flow and O2 saturation in these capillaries. BME PhD student, Nour
Ghonaim, demonstrated that individual capillary units were able to
signal for an increase in O2 supply when capillaries were exposed to low
O2 levels. Since O2 levels in arterioles were not affected this result
supports our hypothesis of a conducted signal from capillaries to
arterioles. Our conclusion is that discrete networks of capillaries,
with the red blood cell as the O2 sensor, are able to regulate upstream
arteriolar resistance to ensure that the distribution of O2 supply
matches the O2 needs of the tissue and that O2 regulation occurs at the
level of capillary units not individual capillaries as proposed by
Krogh.
Bio of the Speaker
Dr. Christopher Ellis graduated from McMaster University in Hamilton
with a B.Eng. degree in Chemical Engineering. In 1980 he completed his
Ph.D. in Chemical Engineering at Northwestern University in Evanston,
Illinois. He began his postdoctoral training with Alan C. Groom in
Biophysics at The University of Western Ontario in 1979 and in 1982 he
was appointed as an Assistant Professor supported initially by a Senior
Scholarship (1982-89) and later a Career Investigator Award of the Heart
and Stroke Foundation of Ontario (1989-94). From 1995 through 2004 he
served as Graduate Chair for Medical Biophysics. From June 2006 to June
2009 he served as Assistant Dean - Research, Schulich School of Medicine
& Dentistry and from July 2009 to December 2009 as Associate Dean -
Research. He is currently a Professor in the Departments of Medical
Biophysics and Medicine.
Dr. Ellis has trained over 20 graduate students, clinical trainees and
post-doctoral fellows. He has published over 80 journal articles with
total of ~3200 citations. His research on oxygen transport in the
microvasculature has been funded by grants from CIHR, Heart and Stroke
Foundation of Ontario, NSERC and NIH. His research interests include
the application of a novel optical imaging system to investigate
microvascular oxygen transport in living tissue in animal models of
disease, the exploration of the mechanisms responsible for the local
regulation of oxygen delivery by the microvasculature in vivo, with
particular emphasis on the role of red blood cell as the sensor and
regulator of oxygen delivery, and the application of microfluidics to
microvascular research.
---
Looking forward to your attendance and support for BME.
Zahra
Zahra Moussavi, Ph.D., P.Eng.
Director, Biomedical Engineering Program
Professor & Canada Research Chair in Biomedical Engineering;
http://umanitoba.ca/biomedical_engineering/
<http://umanitoba.ca/biomedical_engineering/>
Main Office: E3-513 Eng. Bldg. Dept. of Elect. & Comp. Engineering,
University of Manitoba
75 Chancellor Circle, Winnipeg MB R3T 5V6
Phone: 204-474-7023
Fax: 204-261-4639
Email: Zahra_Moussavi(a)Umanitoba.ca <mailto:Zahra_Moussavi@Umanitoba.ca>
http:/home.cc.umanitoba.ca/~mousavi
<http://www.ee.umanitoba.ca/~moussavi>
Research Page: http://bme.ee.umanitoba.ca/bmelab
<http://bme.ee.umanitoba.ca/bmelab>
Riverview Office: PE-458,
1 Morley Ave, Riverview Health Center
Winnipeg, MB
Phone: 478-6163
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
Website: www.sfn-manitoba.ca
Reminder......
Manitoba Neuroscience Network Seminar Series
Friday, May 16, 2014 | 12:00 Noon
[Jerry Silver, Ph.D.]
Dr. Jerry Silver<http://neurowww.cwru.edu/faculty/silver/index>
Professor - Department of Neurosciences
Case Western Reserve University
Topic: Functional regeneration into and beyond the glial scar
Location: Theatre B - Basic Med Sciences Bldg.
Biosketch: Dr. Silver received his Ph.D. from Case Western Reserve in 1974 and was the recipient of the Herbert S. Steuer Memorial Award for Meritorious Original Research in Anatomy. He did post-doctoral work at Harvard University in the Department of Neurosciences at The Children's Hospital and in the Neuropathology Department at Harvard Medical School. Dr. Silver is currently Professor in the Department of Neurosciences at the Case Western Reserve University School of Medicine and adjunct Professor in the Department of Neurosurgery at the Cleveland Clinic Foundation. Dr. Silver is a recipient of several prestigious awards. Dr. Silver has served on a number of editorial boards including the journals Glia, The Journal of Neurocytology, Developmental Neurobiology, The Journal of Neuroscience and Experimental Neurology (where he is a Section Editor). He regularly reviews articles for over 35 high impact journals and he reviews grants for 18 national and international organizations
/sent on behalf of
Eftekhar Eftekharpour
Seminar Coordinator, Manitoba Neuroscience Network
[cid:part1.07040404.07050801@cc.umanitoba.ca]
Kelly Jorundson
Executive Assistant
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939 Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR Kelly.jorundson(a)med.umanitoba.ca<mailto:Kelly.jorundson@med.umanitoba.ca>
Website: www.sfn-manitoba.ca<http://www.sfn-manitoba.ca>
2014 Nick Shepel Student Travel Award
Competition deadline: June 13, 2014
The Nick Shepel Student Travel Award was established by the Division of
Neurodegenerative Disorders, St. Boniface Hospital Research to honor
Nick Shepel who was an outstanding researcher, friend and leader. Nick
was a true inspiration to his lab partners and brought fire, humor, and
a desire to always do better. His insistence to always try better will
have a permanent effect on his lab mates. Nick led by example and taught
that detailed preparation and execution of experiments ensured reliable
results.
Purpose: The purpose of this fund shall be to recognize a young
investigator (graduate student within the Faculty of Medicine -
University of Manitoba) by providing an annual award(s)
(up to $1,000 max) to support travel costs associated with the
applicant's attendance at a future national/international conference
where the applicant is presenting a poster or oral presentation.
Eligibility: At the time of application, students must be registered in
the Faculty of Medicine at the University of Manitoba.
1. "Registered" includes being accepted by the major department of
study, admitted by the Faculty of Graduate Studies, or eligible to
register in the Faculty of Graduate Studies.
2. A student admitted under the "Provisional Status" may not
receive the award during the provisional period.
3. Amount of award(s) may vary each year (minimum value - $400).
4. Students must be giving a poster or oral presentation at an
upcoming scientific meeting (national/international)
Submission Instructions: A complete application consists of the
following:
1. Introductory letter describing meeting
2. Copy of abstract
3. Curriculum vitae
4. Current GPA, transcripts not needed
5. Proposed budget of travel costs
6. Submit your completed application materials to:
Dr. Paul Fernyhough
Director - Division of Neurodegenerative Disorders
St. Boniface Hospital Research
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
How to apply for reimbursement: Reimbursement will be done in
accordance with St. Boniface Hospital travel policies. Only original
receipts will be accepted. Copies may be accepted only where proof of
submission to another agency is provided.
For more information, contact:
Kelly Jorundson, Administrative Manager
Division of Neurodegenerative Disorders
R4046-351 Tache Ave., Winnipeg, MB R2H 2A6
E: kjorund(a)sbrc.ca <mailto:kjorund@sbrc.ca> T:204.235.3939 F:
204.237.4092
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
Website: www.sfn-manitoba.ca
Everyone is invited!
BME seminar - Younes Rakhsani M.Sc.
Date: Thursday, May 8, 2014
Time: 4:00-5:00 PM
Location: E2-330 Engineering Building, Fort Gary Campus
Speaker: Younes Rakhsani M.Sc.
Title: functional Near-Infrared Spectroscopy (fNIRS) for Brain Imaging
Some refreshment will be provided for after the seminar.
To see the list of next scheduled BME seminars, please see here:
http://umanitoba.ca/biomedical_engineering/courses/bme_seminars.html
<http://umanitoba.ca/biomedical_engineering/courses/bme_seminars.html>
Abstract of the talk
Noninvasive measurements of blood volume and blood oxygenation changes
in tissue is possible using near-infrared spectroscopy (NIRS) with high
temporal resolution. Diffuse optical imaging (DOI) is inexpensive and
portable compared to other vascular imaging modalities such as MRI or
positron emission tomography (PET). One of the advantages of the DOS
systems is that they are portable, so it provides the ability to measure
cerebral blood oxygenation, volume, or flow using portable
instrumentation. DOS can be used for different types of bedside
monitoring. Using multi-channel DOS and DOI systems, optical brain
imaging can be applied to various psychology functional tests in adults,
children, and more recently infants.
In this presentation I am going to talk about optical properties of the
brain, basic types of NIRS systems, fNIRS signal processing and
applications of NIRS. Also, I will talk about the CW-NIRS system that we
have built in our lab and its results.
Short Bio of the speaker
Younes received his B.Sc., and first M.Sc. in Electrical engineering
from Iran University of Science and Technology and Tehran University,
respectively. Currently, he is enrolled in the M.Sc. BME program at U of
Manitoba with focus on fNIRS design, implementation and evaluation.
/sent on behalf of
Chris Anderson
Chris M. Anderson,
President - Winnipeg Chapter Society for Neuroscience
Associate Professor and Director, Neuroscience Research Program
Kleysen Institute for Advanced Medicine
Health Sciences Centre and University of Manitoba
T: 204-318-2565
E: chris.anderson(a)med.umanitoba.ca
Everyone is invited to attend!
Manitoba Neuroscience Network Seminar Series - Dr. Jerry Silver
Friday, May 16, 2014 | 12:00 Noon
Theatre B - Basic Med Sciences Bldg.
Dr. Jerry Silver <http://neurowww.cwru.edu/faculty/silver/index>
Professor - Department of Neurosciences
Case Western Reserve University
Topic: Functional regeneration into and beyond the glial scar
Biosketch: Dr. Silver is currently a Professor in the Department of
Neurosciences at the Case Western Reserve University School of Medicine
and adjunct Professor in the Department of Neurosurgery at the Cleveland
Clinic Foundation. Dr. Silver received his Ph.D. from Case Western
Reserve in 1974, with further post-doctoral training at Harvard Medical
School. He is recognized internationally for his long lasting research
in the field of regeneration, spinal cord injury and paralysis.
Dr. Silver is the recipient of several prestigious awards/recognitions
including:
* Herbert S. Steuer Memorial Award (1974)
* Ameritec Prize for significant accomplishments toward a cure for
paralysis (2003)
* Christopher Reeve-Joan Irvine Research Medal (2003), for critical
contributions that may lead to the promotion of repair of the damaged
spinal cord
* Jacob Javits Neuroscience Investigator Award (2004 , that recognizes a
select group of NIH grantees with seminal contributions to their field
of neuroscience
* Erica Nader Award (2008), for breakthrough research in the field of
spinal cord injury
* Member of the American Association for the Advancement of Science
(AAAS) (2011)
Dr. Silver has served on a number of editorial boards including the
journals Glia, The Journal of Neurocytology, Developmental Neurobiology,
The Journal of Neuroscience and Experimental Neurology (where he is a
Section Editor). He regularly reviews articles for over 35 high impact
journals and he reviews grants for 18 national and international
organizations. He has served on a variety of NIH study sections
since 1982 including the Neurobiology Review Group, Neurology B2, The
Visual Sciences C Study Section, and the Clinical Neurology,
Neurotransmitters and Transplantation Study Section. He serves as a
regular member of the Scientific Advisory Council of the Christopher
Reeve Foundation and of the Scientific Board of the International Spinal
Research Trust (England). He has served as lead or senior author
on more than 160 publications.
A brief synopsis of Dr. Silver's work: Over the past several decades,
Dr. Silver has concentrated his research efforts learning whether
molecules that glia produce after spinal cord injury may play a major
role in blocking regeneration. Of particular interest, the chondroitin
sulfate proteoglycans (CSPGs), were first discovered by the Silver's lab
in the early 1990's to be involved in impeding regeneration. His lab has
pioneered the use of the CSPG degrading enzyme chondroitinase to reveal
the important role of the glycosaminoglycan (GAG) sugar chains. Dr.
Silver's lab has shown that adult nerve cells could regenerate their
axons with high efficiency and at high rates of speed even in fully
degenerating white matter and even at long chronic stages after injury,
challenging long held beliefs that this was impossible. Currently, his
research focuses on the regenerative approaches that target the CSPG
receptors. These receptors identified originally by his laboratory may
hold the key for enhancing regeneration after Spinal Cord Injury.
For more information, contact the MNN Office at
(T) 235.3939 or email: mnn(a)sbrc.ca
Presented in co-operation with University of Manitoba
Clinical Neuroscience Rounds
Kelly Jorundson
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939
Fax: 204.237.4092
Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca
Website: www.sfn-manitoba.ca
Dear all,
The 2014 online membership form is now available. If you are not already a member of the Winnipeg Chapter Society for Neuroscience (WCSN), we encourage you to join today.
Click here<http://sfn-manitoba.ca/about.html> to learn more about the benefits of becoming a member .
2014 Fee Schedule:
*Membership fees are for the calendar year (January-December).
Faculty, Professionals
$60.00
Postdocs, Residents, Technicians, Research Associates
$30.00
Students
$15.00
All-inclusive Lab Rate
$100.00
To pay your 2014 membership dues, please complete the WCSN Membership Application<http://sfn-manitoba.ca/application/> . Payment methods include: credit card, cheque, and FOAP.
If you are paying by cheque, please make payment to:
St. Boniface Hospital
c/o Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Regards,
Chris Anderson
President - Winnipeg Chapter Society for Neuroscience
Kelly Jorundson
Executive Assistant
Winnipeg Chapter Society for Neuroscience
R4046 - 351 Tache Avenue
Winnipeg, MB R2H 2A6
Tel: 204.235.3939 Fax: 204.237.4092
Email: kjorund(a)sbrc.ca<mailto:kjorund@sbrc.ca> OR Kelly.jorundson(a)med.umanitoba.ca<mailto:Kelly.jorundson@med.umanitoba.ca>
Website: www.sfn-manitoba.ca<http://www.sfn-manitoba.ca>