Public Seminar: What Can Brain Imaging Tell Us About Dementia?
Presented by leading radiologist
Dr. Marco Essig MD, PhD, FRCPC
Thursday, January 26
7 - 8:30 pm
Samuel N. Cohen Auditorium
St-Boniface Hospital Albrechtsen Research Centre
Brain imaging can be used to detect changes related to mild cognitive
impairment, Alzheimer's dementia, frontotemporal dementia, vascular dementia
and Lewy body dementia. Come to hear how information learned from brain
imaging can assist in the diagnosis and treatment
of dementia.
https://7258.thankyou4caring.org/pages/january-education-2017
Space is limited! Register online at alzheimer.mb.ca
For more information: Call 204-943-6622 or email alzmb(a)alzheimer.mb.ca
<mailto:alzmb@alzheimer.mb.ca>
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Visiting Speaker & Seminar Series
Friday, January 27th, 2017
9:00 a.m.
PX236/238 PsychHealth Bldg., Bannatyne Campus
Dr. Chase Figley
Assistant Professor - Department of Radiology, University of Manitoba
Principal Investigator - Neuroscience Research Program
Core Member - Biomedical Engineering Graduate Program, University of
Manitoba
Adjunct Assistant Professor - Department of Physiology & Pathophysiology,
University of Manitoba
Adjunt Assistant Professor - Department of Psychology, University of
Manitoba
Adjunct Research Scientist - Department of Psychological & Brain Sciences,
Johns Hopkins University
What's new in human neuro-imaging? Recent advances in MRI acquisition,
analysis, and applications
BIO: Chase Figley is currently an Assistant Professor in the Department of
Radiology at the University of Manitoba and a Principal Investigator within
the Neurosci-ence Research Program at the Kleysen Institute for Advanced
Medicine. In addition, he also holds adjunct appoint-ments in Biomedical
Engineering (University of Manitoba), Diagnostic Imaging (Winnipeg Health
Sciences Centre), and the Department of Psycho-logical & Brain Sciences
(Johns Hopkins University). Before moving to Winnipeg in September 2013, he
completed a BSc (Honors) in Chemistry at the University of Saskatchewan
(2001-2005), a PhD in Neuroscience at Queen's University (2005-2010), and a
CIHR-sponsored Postdoctoral Fellowship at Johns Hopkins University
(2010-2013). The ongoing research in his lab is primarily focused on
developing and applying advanced neuroimaging methods - e.g., functional MRI
(fMRI), diffusion tensor imaging (DTI), myelin water imaging (MWI), and
voxel based morphometry (VBM) - to study brain structure and function in
both healthy and clinical populations.
ABSTRACT: Despite major advances in our ability to characterize white
matter microstructure with novel acquisition methods like diffusion tensor
imaging (DTI) and Myelin Water Imaging (MWI), these improvements have not
yet translated into better diagnostic or prognostic capabilities in Multiple
Sclerosis (MS) or other white matter disorders. In other words, more
sophisticated data acquisition methods alone have not overcome the
well-known "clinico-radiological paradox" (i.e., where imaging biomarkers
such as lesion count, lesion volume, etc. do not accurately or reliably
predict patients' clinical outcomes). Fortunately, our knowledge about how
the brain is organized into large-scale functional networks offers a number
of clues about how these problems might be dealt with using more
sophisticated data analysis approaches. In this talk, I will briefly discuss
the organization and topology of these networks in order to suggest that the
locations of white matter lesions - as opposed to the total number or
overall volume, per se - are likely what underlie specific functional
deficits. I will then proceed to describe two new data analysis approaches
that my lab has been working on to: 1) ascribe local white matter changes to
specific functional brain networks, and 2) detect and measure local white
matter changes along white matter tracts. Finally, I will close by
presenting a few recent examples of how these methods have already been used
to study structure-function relationships throughout the brain, and how
white matter alterations in these regions are correlated with individual
differences in body composition and other neuroimaging biomarkers in MS.
/sent on behalf of
Dr. Eftekhar Eftekharpour
Coordinator - MNN Visiting Speaker & Seminar Series Program
eftekhar.eftekharpour(a)umanitoba.ca
<mailto:eftekhar.eftekharpour@umanitoba.ca>
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Please mark your calendars.....
Visiting Speaker & Seminar Series
Friday, February 10, 2017
12:00 NOON.
Apotex Theatre 071, Bannatyne Campus
Dr. James Eubanks
Senior Scientist - Krembil Research Institute Professor - Department of
Surgery,
University of Toronto
Enhancing Excitation To Combat Lost Silencing: Therapeutic Considerations
For Rett Syndrome
***FOLLOWED BY A "NEUROSCIENCE TRAINEE LUNCH" IN SR415 Kleysen Bldg.
BIO: The primary interests of my group relate to defining how the absence of
either methyl DNA binding factor MeCP2, or more recently CDKL5, affects
normal brain function and/or alters the normal progression of brain
development, and to identifying strategies that can be used to correct the
observed alterations. Our work encompasses generating novel transgenic mouse
lines that can be used to address questions relating to our focus, to
testing novel pharmacological agents in established models of Rett syndrome
as part of translational efforts. We are well positioned to assess
therapeutically meaningful endpoints for the translational studies, and have
the skills needed to identify key deficits that can then be subsequently
targeted. It is our intention to identify novel strategies that can someday
be employed to treat patients with Rett syndrome, with the ultimate goal
being condition correction. Our current investigations span several research
disciplines, including cell biology, pharmacology, electrophysiology,
molecular genetics, animal behavior, and live cell imaging.
/sent on behalf of
Dr. Eftekhar Eftekharpour
Coordinator - MNN Visiting Speaker & Seminar Series Program
eftekhar.eftekharpour(a)umanitoba.ca
<mailto:eftekhar.eftekharpour@umanitoba.ca>
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There is a sustained effort being made by the Canadian local chapters of the
Society for Neuroscience to meet regularly to discuss activities and
opportunities. The first meeting was held at the recent SFN conference in
San Diego and the next get-together will be at the Canadian Association for
Neuroscience meeting in Montreal this May. The Chapters agreed that we
would like to involve student members at the next meeting so I am looking
for a PhD student with a strong interest in neuroscience networking,
outreach and education to represent the MNN in Montreal. If you plan to
attend the 2017 CAN meeting and are interested in this opportunity, please
reply to this message. There may be an opportunity for a travel award to
offset some of the travel expenses.
Thank you.
Chris Anderson
MNN President
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