Apologies if you have receive this before but some HSC subscribers are not receiving MNN emails consistently. We will fix this shortly and stop sending duplicates.
One final reminder that the abstract deadline for the 2017 MNN Scientific Meeting is TODAY, May 29 @ 5:00 pm. Please view meeting information, register and submit abstracts at: https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/.
Also a reminder that if you intend to register as a member of the Society for Neuroscience Winnipeg Chapter, you will need to become a 2017 member and create a membership account. If you have been a member in past years, you still must create a membership account for the 2017 membership year. You can do this and then register for the MNN meeting from your account at: https://manitobaneuroscience.ca/sfn-chapter-membership/become-a-sfn-chapter….
Chris Anderson
MNN President
Tabrez Siddiqui
Chair, 2017 MNN Meeting
S E M I N A R & V I S I T I N G S P E A K E R S E R I E S
DATE: Friday, May 26th, 2017
TIME: 9:00 a.m.
LOCATION: PX236/238 PsychHealth Building
***SPEAKER***
MOJGAN RASTEGAR, PH.D
Associate Professor - Department of Biochemistry & Medical Genetics,
Regenerative Medicine Program, University of Manitoba
TOPIC: The bidirectional role of MeCP2 in the brain; a multi layer epigenetic deregulation in MeCP2-associated brain disorders
ABSTRACT: Epigenetic mechanisms control gene expression and brain development without any direct change in the corresponding DNA sequences. Recent discoveries have highlighted the importance of epigenetic mechanisms in brain development, neuroscience, and mental health. MeCP2 is an important epigenetic factor in the brain with a bidirectional functional role that is controlled at multiple levels. While, MeCP2 loss-of-function mutations lead to Rett Syndrome (RTT), its gain-of-function genetic mutations cause MECP2 Duplication Syndrome (MDS) through gene duplication or triplication in the patients. RTT and MDS disorders have overlapping symptoms, and the patients show similar and severe neurological phenotypes that include mental disability, seizers, anxiety, and autism. It is well established that impaired protein translation is a characteristic of human RTT neurons. However, the underlying molecular mechanism of this phenotype is not fully understood. To study the underlying pathobiology of RTT and MDS, my lab investigates the bidirectional role of individual MeCP2 isoforms in controlling fundamental molecular pathways that regulate protein translation. We use a combination of primary neural stem cells, RTT and MDS mouse models, and post-mortem human RTT brain tissues to investigate how molecular deficiencies at the cellular levels lead to compromised brain function in RTT, MDS, and other MeCP2-associated brain disorders including autism.
For more information contact:
Eftekhar Eftekharpour
Coordinator - MNN Seminar & Visiting Speaker Series
789-3214 eftekhar.eftekharpour(a)umanitoba.ca
Sponsored by: Manitoba Neuroscience Network | Health Sciences Centre | University of Manitoba | St. Boniface Research Centre
Kelly Jorundson
Coordinator, Membership & Operations
Manitoba Neuroscience Network
Email: kjorund(a)sbrc.ca
Tel: 204.235.3939
Fax: 204.237.4092
St. Boniface Hospital Albrechtsen Research Centre
Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA
Dear All,
This is a reminder that the Manitoba Neuroscience Network (MNN) is holding its 7th Scientific Meeting June 16 at the Radisson Winnipeg. The 2017 meeting is chaired by Dr. Tabrez Siddiqui and he has assembled a stellar program that includes a featured lecture by one of leaders of the field of neural connectomics, Dr. Jeff Lichtman from Harvard University.
Abstract submission and registration have been open for a couple of weeks. This year there have been several events that may interfere with timely abstract submission and we are seeing numbers that are lower than normal for this stage of the process. We are therefore EXTENDING the abstract deadline once more to MONDAY MAY 29 @ 5 pm. No further extensions will be possible after that because we will need to prepare the programs. As an extra incentive to submit, all trainee posters will be judged and there are several cash poster awards available.
All MNN meeting attendees, including poster presenters, will need to register. The registration deadline is JUNE 5 @ 5 pm. Rates include coffee/snacks, full lunch and an afternoon reception with food. SFN Winnpeg Chapter members pay rates that are discounted by 50% so please become a member for 2017 before you register. PI's, you can purchase a membership for all of your lab members for one price, allowing each person to register for the MNN meeting as an SFN Chapter member.
To LEARN ABOUT THE SFN WINNIPEG CHAPTER AND BECOME A MEMBER: click https://manitobaneuroscience.ca/sfn-chapter-membership/sfn-chapter-membersh…
To VIEW MNN MEETING INFORMATION, SUBMIT YOUR ABSTRACT AND REGISTER: click https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/
Thank you for continuing to make the Manitoba Neuroscience Network a valuable and now award-winning networking and outreach hub! If you have any questions about using the new website for the MNN meeting of SFN Chapter membership, please let us know and we will find the answers.
Sincerely,
Chris Anderson, PhD
MNN President
chris.anderson(a)umanitoba.ca
Tabrez J. Siddiqui, PhD
Chair, 2017 MNN Scientific Meeting
tabrez.siddiqui(a)umanitoba.ca
cid:image001.jpg@01D158FE.B69B8D00
S E M I N A R & V I S I T I N G S P E A K E R S E R I E S
D AT E
Friday, May 26th, 2017
9:00 a.m.
LO C AT I O N
PX236/238
PsychHealth Building
Mojgan Rastegar, Ph.D. <http://rastegar.biochem.umanitoba.ca/>
Associate Professor - Department of Biochemistry & Medical Genetics,
Regenerative Medicine Program, University of Manitoba
Topic: The bidirectional role of MeCP2 in the brain; a multi layer
epigenetic deregulation in MeCP2-associated brain disorders
ABSTRACT:
Epigenetic mechanisms control gene expression and brain development without
any direct change in the corresponding DNA sequences. Recent discoveries
have highlighted the importance of epigenetic mechanisms in brain
development, neuroscience, and mental health. MeCP2 is an important
epigenetic factor in the brain with a bidirectional functional role that is
controlled at multiple levels. While, MeCP2 loss-of-function mutations lead
to Rett Syndrome (RTT), its gain-of-function genetic mutations cause MECP2
Duplication Syndrome (MDS) through gene duplication or triplication in the
patients. RTT and MDS disorders have overlapping symptoms, and the patients
show similar and severe neurological phenotypes that include mental
disability, seizers, anxiety, and autism. It is well established that
impaired protein translation is a characteristic of human RTT neurons.
However, the underlying molecular mechanism of this phenotype is not fully
understood. To study the underlying pathobiology of RTT and MDS, my lab
investigates the bidirectional role of individual MeCP2 isoforms in
controlling fundamental molecular pathways that regulate protein
translation. We use a combination of primary neural stem cells, RTT and MDS
mouse models, and post-mortem human RTT brain tissues to investigate how
molecular deficiencies at the cellular levels lead to compromised brain
function in RTT, MDS, and other MeCP2-associated brain disorders including
autism.
For more information contact:
Eftekhar Eftekharpour
Coordinator MNN Seminar & Visiting Speaker Series
789-3214 eftekhar.eftekharpour(a)umanitoba.ca
Sponsored by:
Manitoba Neuroscience Network | Health Sciences Centre | University of
Manitoba | St. Boniface Research Centre
Kelly Jorundson
Coordinator, Membership & Operations
Manitoba Neuroscience Network
Email: kjorund(a)sbrc.ca
Tel: 204.235.3939
Fax: 204.237.4092
St. Boniface Hospital Albrechtsen Research Centre
Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA
This email and any attachments may contain confidential, personal and/or
privileged information intended for a specific individual and purpose. If
you are not the intended recipient, you are hereby notified that any
disclosure, copying, retaining, distribution, access, use or modification of
the contents of this e-mailed information is strictly prohibited. If you
receive this communication in error, please notify the sender immediately
and delete or destroy the email message and any attachments or copies.
******************************************
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<https://www.facebook.com/manitobaneuroscience/?fref=ts>
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/sent on behalf of Dr. Soheila Karimi
Subject: MS Connect 2017 Research Event in Winnipeg
Hello
I appreciate if you distribute the attached flyer and the note below on my
behalf to MNN and Physiology.
On May 23, 2017, the Multiple Sclerosis Society of Canada has organized an
MS Connect 2017 Research Event in Winnipeg. This public event provides
awareness on recent advances in MS Research.
Dr. Wee Yong, a distinguished researcher in MS and Dr. Arsalan Alizadeh, a
PhD candidate in Dr. Soheila Karimis laboratory, will present their
research findings in this event.
Please join them to learn more about MS research.
This is the link to the event:
https://mssociety.ca/library/image/oFBGA1HiC2rkphU3ELtwSPnz4gQXfTdD/large.jp
g
Thank you
Soheila
--
Soheila Karimi, PhD
Associate Professor of Physiology and Pathophysiology
Principal Investigator, Spinal Cord Injury and Stem Cell Program
Senior Scientist, Regenerative Medicine Program
Principal Investigator, Spinal Cord Research Center
Rady Faculty of Health Sciences
Max Rady College of Medicine
University of Manitoba
Lab Site: http://home.cc.umanitoba.ca/~karimis/
745 Bannatyne Avenue, 629 BMSB
Winnipeg, MB R3E 0J9 Canada
Phone: (204) 272-3109
Kelly Jorundson
Coordinator, Membership & Operations
Manitoba Neuroscience Network
Email: kjorund(a)sbrc.ca
Tel: 204.235.3939
Fax: 204.237.4092
St. Boniface Hospital Albrechtsen Research Centre
Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA
This email and any attachments may contain confidential, personal and/or
privileged information intended for a specific individual and purpose. If
you are not the intended recipient, you are hereby notified that any
disclosure, copying, retaining, distribution, access, use or modification of
the contents of this e-mailed information is strictly prohibited. If you
receive this communication in error, please notify the sender immediately
and delete or destroy the email message and any attachments or copies.
******************************************
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<https://www.facebook.com/manitobaneuroscience/?fref=ts>
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<https://www.instagram.com/manitobaneuroscience/>
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*****C A N C E L L E D *****
Dr. Long-Jun Wu is not able to come to Winnipeg and therefore we have
cancelled his research talk scheduled for today at 12noon.
We are hopeful that Dr. Wu can reschedule his talk for later in the year.
Apologies for any inconvenience.
Kelly
cid:image001.jpg@01D158FE.B69B8D00
S E M I N A R & V I S I T I N G S P E A K E R S E R I E S
D AT E
Friday, May 19th, 2017
12:00 Noon
LO C AT I O N
Theatre C
image008Long-Jun Wu, Ph.D.
<http://www.mayo.edu/research/faculty/wu-longjun-long-jun-ph-d/bio-20305064>
Associate Professor
Department of Neurology, Mayo Medical
School, Mayo Clinic
Topic: Microglia-neuron communication in diseased brain
(to be followed by a TRAINEE LUNCH in room SR415 **Please encourage all
your neuroscience trainees to attend!)
Microglia are the principal immune response cells in the central nervous
system. Resting microglia constantly survey the microenvironment in the
normal brain. Upon brain dysfunction, microglia are activated and exert
detrimental or beneficial effects on the surrounding neurons. However, the
molecular mechanisms for microglial activation and function in brain
diseases are still controversial. The long-term goal of my lab is to
understand microglia-neuron communication in the brain. We are interested in
fundamental questions on: (1) How microglia sense neuronal activities? (2)
How microglia regulate neuronal and synaptic function? (3) What are the
molecular mechanisms and functional consequences of microglia activation in
brain diseases? To address these questions, we use the combination of two
photon deep-brain imaging, electrophysiology, mouse genetics to dissect the
role of microglia in neuronal circuits and in brain disorders. These results
provide a novel insight on microglial function in brain emostasis and
suggest microglia as a potential therapeutic target for the treatment of
brain diseases such as epilepsy, pain and stroke.
For more information contact:
Eftekhar Eftekharpour
Coordinator MNN Seminar & Visiting Speaker Series
789-3214 eftekhar.eftekharpour(a)umanitoba.ca
Sponsored by:
Manitoba Neuroscience Network | Health Sciences Centre | University of
Manitoba | St. Boniface Research Centre
Kelly Jorundson
Coordinator, Membership & Operations
Manitoba Neuroscience Network
Email: kjorund(a)sbrc.ca
Tel: 204.235.3939
Fax: 204.237.4092
St. Boniface Hospital Albrechtsen Research Centre
Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA
This email and any attachments may contain confidential, personal and/or
privileged information intended for a specific individual and purpose. If
you are not the intended recipient, you are hereby notified that any
disclosure, copying, retaining, distribution, access, use or modification of
the contents of this e-mailed information is strictly prohibited. If you
receive this communication in error, please notify the sender immediately
and delete or destroy the email message and any attachments or copies.
******************************************
<http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710
<https://www.facebook.com/manitobaneuroscience/?fref=ts>
cid:image007.png@01D29326.7E26D480
<https://www.instagram.com/manitobaneuroscience/>
cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro>
cid:image010.png@01D29326.7E26D480
cid:image001.jpg@01D158FE.B69B8D00
S E M I N A R & V I S I T I N G S P E A K E R S E R I E S
D AT E
Friday, May 19th, 2017
12:00 Noon
LO C AT I O N
Theatre C
image008Long-Jun Wu, Ph.D.
<http://www.mayo.edu/research/faculty/wu-longjun-long-jun-ph-d/bio-20305064>
Associate Professor
Department of Neurology, Mayo Medical
School, Mayo Clinic
Topic: Microglia-neuron communication in diseased brain
(to be followed by a TRAINEE LUNCH in room SR415 **Please encourage all
your neuroscience trainees to attend!)
Microglia are the principal immune response cells in the central nervous
system. Resting microglia constantly survey the microenvironment in the
normal brain. Upon brain dysfunction, microglia are activated and exert
detrimental or beneficial effects on the surrounding neurons. However, the
molecular mechanisms for microglial activation and function in brain
diseases are still controversial. The long-term goal of my lab is to
understand microglia-neuron communication in the brain. We are interested in
fundamental questions on: (1) How microglia sense neuronal activities? (2)
How microglia regulate neuronal and synaptic function? (3) What are the
molecular mechanisms and functional consequences of microglia activation in
brain diseases? To address these questions, we use the combination of two
photon deep-brain imaging, electrophysiology, mouse genetics to dissect the
role of microglia in neuronal circuits and in brain disorders. These results
provide a novel insight on microglial function in brain emostasis and
suggest microglia as a potential therapeutic target for the treatment of
brain diseases such as epilepsy, pain and stroke.
For more information contact:
Eftekhar Eftekharpour
Coordinator MNN Seminar & Visiting Speaker Series
789-3214 eftekhar.eftekharpour(a)umanitoba.ca
Sponsored by:
Manitoba Neuroscience Network | Health Sciences Centre | University of
Manitoba | St. Boniface Research Centre
Kelly Jorundson
Coordinator, Membership & Operations
Manitoba Neuroscience Network
Email: kjorund(a)sbrc.ca
Tel: 204.235.3939
Fax: 204.237.4092
St. Boniface Hospital Albrechtsen Research Centre
Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA
This email and any attachments may contain confidential, personal and/or
privileged information intended for a specific individual and purpose. If
you are not the intended recipient, you are hereby notified that any
disclosure, copying, retaining, distribution, access, use or modification of
the contents of this e-mailed information is strictly prohibited. If you
receive this communication in error, please notify the sender immediately
and delete or destroy the email message and any attachments or copies.
******************************************
<http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710
<https://www.facebook.com/manitobaneuroscience/?fref=ts>
cid:image007.png@01D29326.7E26D480
<https://www.instagram.com/manitobaneuroscience/>
cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro>
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