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Reminder: MNN Seminar - Dr. Larry Jordan
by Winnipeg Chapter Society for Neuroscience 24 Nov '11

24 Nov '11

PLEASE CIRCULATE: Winnipeg Chapter Society for Neuroscience presents..... Manitoba Neuroscience Network Meeting Friday, November 25th, 2011 9:00 - 10:00am Dr. Larry Jordan Professor, Department of Physiology University of Manitoba Topic: Control of locomotion by a serotonergic pathway arising in the parapyramidal region of the medulla Location: PX236/238 PsychHealth, Bannatyne Campus Brief Bio: Born in Paris, Texas, in 1944, I grew up in Texarkana, Texas, the son of a bakery worker/farmer and a first grade teacher. I earned a B.A. degree in zoology at the University of Texas at Austin, and then entered graduate studies at The University of Texas Southwestern Medical School in Dallas, where I was supervised by William D. Willis, Jr., a student of John Eccles in Canberra, Australia, and a former President of the Society for Neuroscience. I moved to Winnipeg in 1970 to assume a post-doctoral position with Dr. John Phillis, also trained in Canberra, who was a pioneer in CNS neuropharmacology. John moved to Saskatoon to take up the position of Head of Physiology there, and I remained in Winnipeg, supported by a Medical Research Council Scholarship. Since that time I was able to participate in the creation of the Winnipeg Spinal Cord Research Centre (http://www.scrc.umanitoba.ca/), with funding from the Health Sciences Centre Research Foundation, the annual Will-to-Win Golf Tournament (2012 will be its 29th year!), the Canadian Institutes for Health Research, the International Human Frontier Science Program, the Canadian Network of Centres of Excellence, and the U.S. National Institutes of Health. I was the PI in the Canadian Institutes of Health Research Group on Spinal Cord Functional Systems for a number of years. I initiated the formation of the Winnipeg Chapter of the Society for Neuroscience, and I served two terms as Head of the Department of Physiology at the University of Manitoba (1992-2001). My research has focused on the neural control of locomotion, with progress along three major lines of investigation: (1) identification of the brain areas and neural pathways responsible for providing descending messages for the initiation of locomotion, (2) the study of spinal cord neurons that control locomotion at the spinal level and (3) discovery of new physiological properties of spinal motoneurons and interneurons that are central to their recruitment during locomotion. I am currently focusing on a descending pathway from a discrete serotonergic nucleus in the medulla that is involved in the initiation of locomotion and in control of inter- and intralimb coordination, and I am doing experiments to evaluate the potential of these neurons to restore coordinated locomotor movements after transplantation into the spinal cord of paraplegic rats. For more information on Dr. Jordan's research, visit his website at: http://umanitoba.ca/faculties/medicine/physiology/contacts/jordan.html Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 T: 204.235.3939 f: 204.237.4092 Email: wcsn(a)sbrc.ca Website: sfn-manitoba.ca

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(no subject)
by Winnipeg Chapter Society for Neuroscience 21 Nov '11

21 Nov '11

The Thirteenth Annual Norman Hill Lecture December 2, 2011 8:00 am to 9:00 am Theatre PX236/238, PsycHealth 771 Bannatyne Avenue This Year's Guest Speaker: Rajiv Midha, MD, MSc, FRCSC Professor and Deputy Head in the Department of Clinical Neurosciences and Chief of the Division of Neurosurgery at the University of Calgary Presenting: "Experimental and Clinical Advances in Nerve Repair" Refreshments 9:00 am to 10:00 am at The Joe Doupe Concourse (the east side of Theatre A on the 2nd Floor, Basic Medical Sciences Bldg) This Lecture is open to everyone. For further details contact: Karla Patterson at 787-7265 Karla Patterson Program Administrator Postgraduate Training Program SECTION OF NEUROSURGERY University of Manitoba GB134 - 820 Sherbrook Street Winnipeg MB R3A 1R9 PH#: (204) 787-7265 FAX#: (204) 787-3851 E-MAIL: kpatterson(a)exchange.hsc.mb.ca Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 T: 204.235.3939 f: 204.237.4092 Email: wcsn(a)sbrc.ca Website: sfn-manitoba.ca

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MNN Seminar Notice - Dr. Larry Jordan
by Winnipeg Chapter Society for Neuroscience 21 Nov '11

21 Nov '11

Please see attached poster missed from earlier email PLEASE CIRCULATE: Winnipeg Chapter Society for Neuroscience presents..... Manitoba Neuroscience Network Meeting Friday, November 25th, 2011 9:00 - 10:00am Dr. Larry Jordan Professor, Department of Physiology University of Manitoba Topic: Control of locomotion by a serotonergic pathway arising in the parapyramidal region of the medulla Location: PX236/238 PsychHealth, Bannatyne Campus For more information on Dr. Jordan's research, visit his website at: http://umanitoba.ca/faculties/medicine/physiology/contacts/jordan.html Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 T: 204.235.3939 f: 204.237.4092 Email: wcsn(a)sbrc.ca Website: sfn-manitoba.ca

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MNN Seminar: Dr. Larry Jordan this Friday
by Winnipeg Chapter Society for Neuroscience 21 Nov '11

21 Nov '11

PLEASE CIRCULATE: Winnipeg Chapter Society for Neuroscience presents..... Manitoba Neuroscience Network Meeting Friday, November 25th, 2011 9:00 - 10:00am Dr. Larry Jordan Professor, Department of Physiology University of Manitoba Topic: Control of locomotion by a serotonergic pathway arising in the parapyramidal region of the medulla Location: PX236/238 PsychHealth, Bannatyne Campus For more information on Dr. Jordan's research, visit his website at: http://umanitoba.ca/faculties/medicine/physiology/contacts/jordan.html Poster to follow shortly.... Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 T: 204.235.3939 f: 204.237.4092 Email: wcsn(a)sbrc.ca Website: sfn-manitoba.ca

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Reminder: Research Seminar Friday Nov 4 12:00 noon
by Winnipeg Chapter Society for Neuroscience 31 Oct '11

31 Oct '11

Everyone is invited.... Seminar Series Dr. Julia Rempel Director, Liver Research Program Assistant Professor, Dept Medicine/Immunology University of Manitoba "Hepatitis C virus and interferon treatment induced neuropsychiatric disorders" Friday, November 04 12:00 - 13:00 Pharmacology Library - Room A229 Chown Building ** **Video-linked to St. Boniface Research Centre Room R1002 Bio: Dr. Julia Rempel received her PhD at The University of Manitoba in the Department of Immunology in 1999 (Kent HayGlass supervisor). She did her post-doctoral fellowship at the Scripps Research Institute, La Jolla, CA, examining how viruses can cause disease through activating deleterious pro-inflammatory immune responses in mouse models of encephalitis. During this time, reports emerged suggesting that despite a high burden of infectious disease within Aboriginal peoples, Aboriginal ancestry allowed for more effective clearance of hepatitis C virus infection. Intrigued, she returned to Manitoba in 2002 as a member of the Section of Hepatology to study the interaction of Aboriginal immunity and hepatitis C infection. Her laboratory (dubbed the OOH-QUIN Immunology Laboratory, OOH-QUIN means liver in Cree and Oji-cree) has been/is at the forefront in unveiling how immune genetics and function influences disease outcomes in Aboriginal populations. She has received national grants from CIHR and the Canadian Liver Foundation, as well as local and pharmaceutical funding. The trainees within her laboratory have also received numerous awards and fellowships. In addition to scientific publications, she has made extensive contributions to knowledge translation within the Aboriginal community, including the production of a research video in Oji-cree. Abstract of Research Interests: The cornerstones of Dr. Rempel's research program are innate immunity, liver disease, and Aboriginal health. The primary focus of her laboratory has been exploring immune processes in the enhanced ability of Aboriginal people's to spontaneously clear hepatitis C virus relative to other peoples. With a combination of genetic and cell behavior assays, her research team found that immune cells from Aboriginal peoples have a greater genetic tendency to pro-inflammatory immunity and a reduced susceptibility to hepatitis C virus protein deregulation relative to Caucasian population controls. These ongoing studies involve Aboriginal communities, as well as partners from the University of Manitoba, the National Microbiology Laboratory (NML) and inner city clinics. Clinical studies in collaboration with the Section of Hepatology and Viral Hepatitis Investigation Unit continue to evaluate immune responses of Aboriginal and Caucasian patients undergoing treatment for chronic hepatitis C infection. As part of these studies, they are considering the potential of baseline immunity to predict therapeutic clearance and neuropsychiatric side effects. More recently, her team has been concerned with the negative consequences of a highly pro-inflammatory immune environment within the Aboriginal population. To this end, they are working with the Pediatric Diabetes Unit to examine immunopathogenesis in type 2 diabetes of Aboriginal youth. Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 T: 204.235.3939 f: 204.237.4092 Email: wcsn(a)sbrc.ca Website: sfn-manitoba.ca

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Manitoba Neuroscience Network Seminars Series - 2011/2012
by Winnipeg Chapter Society for Neuroscience 24 Oct '11

24 Oct '11

Winnipeg Chapter Society for Neuroscience presents2012 Schedule (Presented in co-operation with University of Manitoba Clinical Neuroscience Rounds ) Manitoba Neuroscience Network Seminar Series - 2011/2012 **All seminars are held last Friday of each month 9:00 - 10:00 am Rm PX236/238 Psych Health Bldg, Bannatyne Campus** ------------------------------------------------------------------------ ----------------------- Date Speaker September 30, 2011 Dr. Brent Fedirchuk Associate Professor, Department of Physiology University of Manitoba October 28, 2011 Dr. Mark Fry Assistant Professor, Department of Biological Sciences University of Manitoba November 25, 2011 Dr. Larry Jordon Professor, Department of Physiology University of Manitoba January 27, 2012 Dr. Xin-Min Li Medical Director, IMG Program Professor, Department of Psychiatry University of Manitoba February 24, 2012 Dr. Sari Hannila Assistant Professor, Department of Human Anatomy & Cell Sciences, University of Manitoba March 30, 2012 Dr. Gordon Glazner Associate Professor - Department of Pharmacology & Therapeutics, University of Manitoba ril 27, 2012 OPEN May 25, 2012 Dr. Jiming Kong Associate Professor - Department of Human Anatomy & Cell Sciences, University of Manitoba For more information contact the MNN office mnn(a)sbrc.ca or (T) 235.3939 Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 T: 204.235.3939 f: 204.237.4092 Email: wcsn(a)sbrc.ca Website: sfn-manitoba.ca

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MNN Seminar - Dr. Mark Fry
by Winnipeg Chapter Society for Neuroscience 20 Oct '11

20 Oct '11

Manitoba Neuroscience Network Seminar: DR. MARK FRY Friday, October 28th, 2011 | 9:00 - 10:00am DR. MARK FRY Assistant Professor, Department of Biological Sciences University of Manitoba Topic: Roles of the subfornical organ in regulating energy balance. Location: PX236/238 PsychHealth, Bannatyne Campus The main focus of the research carried out in the lab is to understand the physiology of neurons that regulate homeostasis. In particular, the lab is interested in understanding regulation of electrical activity in neurons that control food intake and other aspects of energy homeostasis. Neurons of the sensory circumventricular organs (CVOs) are thought to be especially important for regulation of homeostasis because these neurons are not protected by the blood-brain barrier, and are able to sense hunger-stimulating and satiety (hunger-ending) hormones circulating in the bloodstream. A second focus of research aims to understand roles of different ion channels in the regulation of electrical excitability of neurons. Ion channels are proteins in neuronal cell membranes that undergo conformational changes to form a pore that allows charged ions such as Na+, Ca++, K+ and Cl- to flow into or out of the cell. These "ionic currents" are the basis of the neuronal action potential and neuronal communication within the CNS. There is a large diversity of ion channels: dozens of ion channel gene families have been described, and many families have numerous isoforms. These isoforms exhibit only subtle structural differences, but often exhibit dramatic functional differences. Populations of neurons may express vastly different complements of these isoforms and the relationship between ion channel isoform expression and the patterns of neuronal electrical activity is only beginning to be understood. Acutely modulating neuronal ion channel properties by activating intracellular signalling pathways or by changing expression patterns of ion channels by disease or other stimulus can result in dramatic changes in neuronal function. For more information, contact the MNN Office at (T) 235.3939 or email: mnn(a)sbrc.ca Presented in co-operation with University of Manitoba Clinical Neuroscience Rounds Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 T: 204.235.3939 f: 204.237.4092 Email: wcsn(a)sbrc.ca Website: sfn-manitoba.ca

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REMINDER: DND Invited Speaker - Dr. Jaideep Bains
by Winnipeg Chapter Society for Neuroscience 06 Oct '11

06 Oct '11

Everyone is invited..... (Hosted by the Division of Neurodegenerative Disorders <http://www.sbrc.ca/content/blogcategory/38/51/> , St. Boniface Hospital Research) Dr. Jaideep Bains <http://www.hbi.ucalgary.ca/members/bains> Professor, Hotchkiss Brain Institute & Dept Physiology & Pharmacology, University of Calgary Topic: Synapses and the stress response. Friday, Oct. 7th, 2011 12:00 NOON Theatre "C" BMSB Bannatyne Campus Bio - Professor, Hotchkiss Brain Institute and Department of Physiology & Pharmacology, University of Calgary - Member of CIHR Institute of Neuroscience Mental Health and Addiction Institute Advisory Board - PhD Queen's University 1997 - Human Frontiers and Epilepsy Foundation of America Postdoctoral - Fellow, University of Colorado Health Sciences Center, Denver, CO 1997-2001 Research Interests: The goal of my lab is to understand how physiological and behavioural challenges lead to long-term changes in neural circuitry. We focus on neurons that coordinate an organism's response to stress, with a particular interest in clarifying how the molecules released at the onset of a stressful stimulus leave a lasting imprint on how 'stress-relevant' circuitry functions. Within this context, we conduct experiments that will allow us to understand the fundamental rules that govern cell to cell communication within the hypothalamus and elucidate the molecular machinery that contributes to changes in synaptic function which, in turn, may be critical for changing network output.

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Reminder: Dr. Jaideep Bains talk Friday Oct 7 2011
by Winnipeg Chapter Society for Neuroscience 03 Oct '11

03 Oct '11

everyone is invited.... Division of Neurodegenerative Disorders Visiting Speaker: Dr. Jaideep Bains Dr. Jaideep Bains Professor, Hotchkiss Brain Institute & Dept Physiology & Pharmacology, University of Calgary Friday, Oct. 7th, 2011 12:00 NOON Theatre "C" BMSB Bannatyne Campus Topic: Synapses and the stress response. pic: Bio: PhD Queen's University 1997 Human Frontiers and Epilepsy Foundation of America Postdoctoral Fellow, University of Colorado Health Sciences Center, Denver, CO 1997-2001 Currently: Professor, Hotchkiss Brain Institute and Department of Physiology & Pharmacology, University of Calgary Member of CIHR Institute of Neuroscience Mental Health and Addiction Institute Advisory Board or more information Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 T: 204.235.3939 f: 204.237.4092 Email: wcsn(a)sbrc.ca Website: sfn-manitoba.ca

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Reminder tomorrow: MNN MEETING Dr. Brent Fedirchuk
by Winnipeg Chapter Society for Neuroscience 29 Sep '11

29 Sep '11

Dr. Brent Fedirchuk Associate Professor, Department of Physiology University of Manitoba Friday, September 30th, 2011 9:00 - 10:00am PX 236/238 Psychiatry Bldg. Bannatyne Campus Topic: The facilitation of motor output by the regulation of spinal motoneuron excitability. Summary of Research: Dr. Brent Fedirchuk's Summary of Research: * Dr. Fedirchuk's research is aimed at determining the factors regulating the excitability of spinal neurons and determining how this regulation contributes to the production of useful motor output, such as locomotion. Using single-cell electrophysiological recording techniques coupled with experimental preparations able to exhibit complex motor activity, Dr. Fedirchuk and colleagues have been able to demonstrate a rapid and reversible enhancement of the excitability of spinal neurons from descending and intrinsic spinal systems. * Dr. Fedirchuk is a native Manitoban, and received a B.Sc. (Hons) in Zoology from the University of Manitoba, followed by M.Sc. and Ph.D. degrees working with Dr. Susan Shefchyk in the Department of Physiology (University of Manitoba). Dr. Fedirchuk then undertook postdoctoral training (CIHR Fellowship) with Dr. Hans Hultborn (Copenhagen) and Dr. Michael O'Donovan (NIH). Dr. Fedirchuk was recruited back to Winnipeg, initially as a Research Associate in Dr. Larry Jordan's laboratory, and subsequently as an Assistant Professor. Dr. Fedirchuk is currently an Associate Professor in the Department of Physiology, University of Manitoba. Location: PX236/238 Psychiatry Bldg. For more information, contact the MNN Office at (T) 235.3939 or email: mnn(a)sbrc.ca Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 T: 204.235.3939 f: 204.237.4092 Email: wcsn(a)sbrc.ca Website: sfn-manitoba.ca

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