- Neuro-All - University of Manitoba Mailing Lists

MNN Seminar - Dr. Xin-Min Li Friday Mar 22 | 9am
by Winnipeg Chapter Society for Neuroscience 08 Mar '13

08 Mar '13

Manitoba Neuroscience Network - Seminar Series Friday, March 22nd, 2013 | 9:00 a.m. Dr. Xin-Min Li <http://www.umanitoba.ca/faculties/medicine/units/psychiatry/research/ab out_xin-min_li.html> Professor - Department of Psychiatry University of Manitoba TOPIC: "Depression: from clinical guidelines to neurobiology." Location: PX236/238 Psychiatry Bldg. Biosketch: Dr. Xin-Min Li is a Professor and Ruth Hurd Chair in the Department of Psychiatry and Assistant Dean of the International Graduate Program at the University of Manitoba. Dr. Li is currently the Director of the Neuroscience Research Program at the Faculty of Medicine, and holds a cross appointment in the Department of Human Anatomy and Cell Science. Dr. Li received his M.D. and PhD in Physiology at Norman Bethune University of Medical Sciences in Changchun, China and completed his residency in Psychiatry at University of Saskatchewan. Dr. Li completed postdoctoral training in the Department of Psychiatry at University of Saskatchewan and at Harvard University. Dr. Li began his academic career at University of Saskatchewan as Assistant Professor (1992) and was Director of the Neuropsychiatric Research Unit prior to moving to University of Manitoba in 2007. Dr. Li's research interests are primarily biological psychiatry. His research uses animal models to examine the role of white matter and neurodegeneration in mood disorders and schizophrenia using cellular, molecular, microMRI imaging, and behavioural assessment techniques. He also studies the mechanisms of treatment in psychiatric and neurodegenerative diseases, focusing on the neuroprotective effects of antidepressants and atypical antipsychotics. His work includes research collaborations in North America and China. Dr. Li has received research support from Canadian Institute of Health Research (CIHR), Manitoba Health Research Council (MHRC), Canadian Psychiatric Research Foundation (CPRF), Alzheimer's Society of Canada, Schizophrenia Societies, as well as the pharmaceutical industry. Dr. Li has a successful track record in developing successful strategic research partnerships and spearheaded the development of the highly successful Schizophrenia Research Program Partnership and the Anxiety and Depression Research Initiative. For more information, contact the MNN Office at (T) 235.3939 or email: mnn(a)sbrc.ca Presented in co-operation with University of Manitoba Clinical Neuroscience Rounds Kelly Jorundson Executive Assistant Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 Tel: 204.235.3939 Fax: 204.237.4092 Email: kjorund(a)sbrc.ca Website: www.sfn-manitoba.ca

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MNN Seminar Reminder - note that the talk will be at 2pm Theatre B
by Winnipeg Chapter Society for Neuroscience 21 Feb '13

21 Feb '13

Manitoba Neuroscience Network Seminar Series - DR. DEREK VAN DER KOOY Friday, February 22nd, 2013 | 2:00 Location: Theatre B, Basic Sciences Bldg. Bannatyne Campus Topic: Where Brains Come From Dr. Derek van der Kooy is Professor - Department of Molecular Genetics, University of Toronto For more information, please see attached notice. Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 Tel: 204.235.3939 Fax: 204.237.4092 Email: kjorund(a)sbrc.ca <mailto:kjorund@sbrc.ca> OR kjorund(a)yahoo.ca <mailto:kjorund@yahoo.ca>

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upcoming talks & student lunch
by Winnipeg Chapter Society for Neuroscience 20 Feb '13

20 Feb '13

Couple reminders..... Manitoba Neuroscience Network Seminar Series - DR. DEREK VAN DER KOOY Friday, February 22nd, 2013 | 2:00 noon Location: Theatre B, Basic Sciences Bldg. Bannatyne Campus Topic: Where Brains Come From Dr. Derek van der Kooy is Professor - Department of Molecular Genetics, University of Toronto For more information, please see attached notice. ------------------------------------------- Edge of Science and Medicine Seminar Series - DR. DETLEY BOISON Monday, February 25, 2013 | 12:00 - 1:00 PM Location: Theatre B, Basic Sciences Bldg. Bannatyne Campus TOPIC: Therapeutic Epilepsy Research: Focus on Adenosine. **A STUDENT LUNCH*** WILL Follow at 1:15-2:15 PM in Pharmacology and Therapeutics Library, A229 Chown Building (please RSVP to raquel.nowlin(a)med.umanitoba.ca ASAP) Dr. Detlev Boison - Interim Dow Chair of Neurology & Director of Neurobiology Research Director of Basic and Translational Research, Legacy Research Institute Adjunct Professor - Oregon Health & Science University, Portland, OR For more information, please see attached notice. Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 Tel: 204.235.3939 Fax: 204.237.4092 Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca

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Goldowitz Seminar
by Winnipeg Chapter Society for Neuroscience 14 Feb '13

14 Feb '13

/sent on behalf of Geoff Hicks..... Dear Colleagues, I want to bring your attention to a visiting professor seminar next week by Dr Dan Goldowitz (poster attached). Would be terrific if you could send the seminar notice out to your own email list. I have taken the liberty to include the faculty's neuroscience programs as "co-hosts," recognizing that his seminar may be of high interest to your research groups. Please also note, all trainees (and in particular those in your own programs) are invited to join later in the afternoon for a Developmental Biology class lecture on brain development and neuro-developmental diseases. This will be followed by a robust open discussion and plenty of time to interact with Dr Goldowitz. Dan has quite a full day, but please let me know if you would like to meet with him personally, and I'll be happy to make whatever arrangements I can. with best regards, Geoff Hicks, PhD Director, Regenerative Medicine University of Manitoba Office: 204-787-2133 Fax: 204-787-2190 Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 Tel: 204.235.3939 Fax: 204.237.4092 Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca

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FW: Student Seminar/Lunch
by Winnipeg Chapter Society for Neuroscience 12 Feb '13

12 Feb '13

please pass along to your neuroscience students.... Dear Neuroscience students, You are invited to attend a student lunch following the Edge of Science Seminar on Monday February 25, 2013. The Lunch will be held in the Pharmacology and Therapeutics Library A229 Chown Building at 1:15 pm. Please RSVP if you will be attending by Friday February 15, 2013. Please note: If you are planning to attend the lunch ,you are also required to attend the seminar. Best Regards, Raquel Nowlin Department of Pharmacology & Therapeutics Faculty of Medicine University of Manitoba A203-753 McDermot Avenue Winnipeg MB R3T 0T6 Phone: 204-789-3520 Fax: 204-789-3932 Email: raquel.nowlin(a)med.umanitoba.ca Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 Tel: 204.235.3939 Fax: 204.237.4092 Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca

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Neuroscience Seminar Series - Feb. 22nd
by Winnipeg Chapter Society for Neuroscience 12 Feb '13

12 Feb '13

**Please note time/location change for this seminar. Manitoba Neuroscience Network Seminar Series Friday, February 22nd, 2013 | 2:00 pm Dr. Derek van der Kooy Professor Department of Molecular Genetics University of Toronto Topic: Where Brains Come From Location: Theatre B Derek van der Kooy served as Professor in the Department of Anatomy and Cell Biology at the University of Toronto from 1991 until 2002, when he became a Professor in the Department of Molecular Genetics. Derek received a M.Sc. in Psychology at the University of British Columbia, and a Ph.D in Anatomy, first at Erasmus University in the Netherlands, and finishing in the Department of Anatomy at the University of Toronto. Dr. van der Kooy gained postdoctoral research experience at Cambridge University in England and at the Salk Institute in California. The van der Kooy lab works on various stem cell biology and developmental biology research projects; specifically, stem cells in organisms from Drosophila to humans. We produced the first report of stem cells in the adult mammalian eye, published in 2000 in Science. We also have isolated a rare stem cell from the adult mouse and human pancreas that can show extensive proliferation under defined conditions in vitro. Of interest to the lab is the lineage of neural stem cells from pluripotent embryonic stem cells, with relevance to the origin of the earliest neural stem cell in the developing embryo. ABSTRACT: One of the few neurobiological facts not anticipated by Cajal is the existence of neural stem cells in the embryonic and adult mammalian brain that can produce new neurons in the adult brain (new neurons first shown by Altman). The earliest mammalian neural stem cells differentiate from pluripotent embryonic stem cells. These primitive neural stem cells emerge in response to LIF and have a wider non-neural phenotypic potential than later neural stem cells. By embryonic day 8.5 in mouse, true FGF2 dependent neural stem cells emerge and by embryonic day 14 they have given rise to copies of themselves and to EGF dependent neural stem cells. The separate FGF2 and EGF dependent neural stem cells increase greatly in numbers later in neurogenesis, but by E14 appear identical to adult neural stem cells. The adult mammalian neural stem cells are mostly quiescent, dividing asymmetrically only once every few weeks. Mouse embryonic stem (ES) cells cultured in low cell density, completely defined media adopt a neural identity. Using a clonal colony-forming assay, we identify the novel primitive neural stem cell stage as a component of neural lineage specification (this cell is similar to the one we isolate from the early embryo), which is negatively regulated by TGFb-related signaling. These results are consistent with a default mechanism for neural fate specification. Primitive neural stem cells are formed directly from single ES cells in a LIF-dependent manner, express multiple neural precursor markers and give rise to neurons and glia. Moreover, in vivo mouse chimera experiments reveal that these primitive ES-derived neural stem cells have a broad range of neural and non-neural lineage potential. These results support a model whereby definitive neural stem cell formation is preceded by a primitive neural stem cell stage during neural lineage commitment. Most recently, we have found that the LIF-dependent, primitive neural stem cells persist in adult organisms and can repopulate a depleted definitive neural stem cell pool in the adult. For more information, contact the MNN Office at (T) 235.3939 or email: mnn(a)sbrc.ca Presented in co-operation with University of Manitoba Clinical Neuroscience Rounds Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 Tel: 204.235.3939 Fax: 204.237.4092 Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca From: Krystyna Kruczek [mailto:KKruczek@exchange.hsc.mb.ca] Sent: February 12, 2013 10:48 AM To: Kelly Jorundson Subject: FW: Neuroscience Seminar Series - Feb. 22nd Hi Kelly, I am sending out the notice for February 22nd Neuroscience Rounds as Marie is away. Can you email me the information I need on the Neuroscience Seminar Series for that day? Thanks. Krys Kruczek Administrative Assistant to, Neil Berrington, MMed, FRCS, FCS (SA) Assistant Professor Head - Section of Neurosurgery Phone: 204-787-7261 Fax: 204-787-3851 Email: KKruczek(a)exchange.hsc.mb.ca P Please consider the environment before printing this email From: Marie Field Sent: Wednesday, February 06, 2013 9:39 AM To: Krystyna Kruczek Subject: Neuroscience Seminar Series Hi Krys, I receive info re the Neuroscience Seminar Series from: Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 Tel: 204.235.3939 Fax: 204.237.4092 Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca I appreciate you contacting her for the February 22nd info and for sending out the Neuroscience Rounds notice while I am away. _______________________________ Marie Field Education Coordinator Dermatology, Infectious Diseases, Neurology and Physician Assistant Program Department of Internal Medicine University of Manitoba GF328, Health Sciences Centre Tel: (204) 787-8624 l Fax: (204) 787-4528 mfield(a)hsc.mb.ca

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New Neuroscience Funding Opportunity: The W. Garfield Weston Foundation
by Winnipeg Chapter Society for Neuroscience 07 Feb '13

07 Feb '13

This message is forwarded on behalf of Alexandra Stewart Executive Director, Neuroscience The W. Garfield Weston Foundation ------------------------------------ I am writing as the Executive Director, Neuroscience of The W. Garfield Weston Foundation. The Foundation is a private Canadian family foundation where donations are directed to qualified donees in the fields of education, land conservation, science in Canada's North and through unsolicited Trustee Initiated Grants. Last year, the Foundation launched a pilot funding program for neuroscience research within the Greater Toronto Area. I am excited to let you know the Foundation is launching another pilot funding program for neuroscience research this week open to institutions across Canada. We wanted to ensure you and the researchers at the University of Manitoba were aware of this opportunity. The goal of this request for proposals (RFP) is to provide funding for translational research or clinical trials that will have transformational impact in neurodegenerative diseases of aging. The Foundation will commit up to $4 million to this program. Grants will be for up to $500,000 per year for up to three years to a maximum of $1.5 million per project. Application requires a one to two page Letter of Intent due Monday, March 25th, 2013. High potential applicants will be invited to submit a short proposal, and grantees will be announced in the summer. Details are attached and are also at www.westonfoundation.org/pages/neuroscience.aspx<http://www.westonfounda tion.org/pages/neuroscience.aspx>. Please let me know if a follow up phone call would be helpful. Questions about the RFP are also welcome at info(a)westonneuroscience.ca<mailto:info@westonneuroscience.ca> or 416 935-4056. Best wishes, Alex Alexandra Stewart Executive Director, Neuroscience The W. Garfield Weston Foundation 22 St. Clair Avenue East, Suite 2001 Toronto, ON M4T 2S3 alexandra.stewart(a)weston.ca<mailto:alexandra.stewart@weston.ca> w: 416 922-1383 x 5764 f: 416 967-7949 <<Transformational RFP on Neurodegenerative Diseases of Aging.docx>> <<ATT00001.htm>>

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Dr. Derek van der Kooy's visit
by Winnipeg Chapter Society for Neuroscience 30 Jan '13

30 Jan '13

Dear All, As you may know, The Manitoba Neuroscience Network will be hosting Dr. Derek van der Kooy on Feb 22, 2013. He is currently a Professor at the Department of Medical Genetics. Dr. van der Kooy is one of the pioneers of the field of adult stem cells. His publications in the field of Neural stem cells, Retinal stem cells and pancreatic stem cells are published in top journals such as Cell, Science, Nature, Neuron,Development and J Neuroscience are highly cited. Dr. van der Kooy is also a great speaker and I will hope that you will try to attend his lecture on Feb 22, at noon, Room 626 in Regenerative Medicine. I am trying to schedule his short day visit on Feb 22nd and therefore I am asking those interested in meeting him to contact me at eftekhar(a)cc.umanitoba.ca. We may have to arrange for group meetings if individual meetings are not possible. The meetings will be planned in a meting room in Regen Med for the sake of time. Thank you for your time, Regards --

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Upcoming neuroscience-related talks....
by Winnipeg Chapter Society for Neuroscience 28 Jan '13

28 Jan '13

Edge of Science and Medicine Seminar Series | Dr. Paul Fernyhough Monday, February 04, 2013 12:00 - 1:00 PM Theatre B - Basic Medical Sciences Dr. Paul Fernyhough Professor - Departments of Pharmacology and Therapeutics & Physiology University of Manitoba Director, Division of Neurodegenerative Disorders -St. Boniface Research Centre TOPIC: Drug discovery for neurological disease ------------------------------------------------------------- Manitoba Neuroscience Network Seminar Series | Dr. Derek van der Kooy Friday, February 22nd, 2013 | 12:00 noon Location: Regenerative Medicine Lecture Theatre (626 BMSB) Dr. Derek van der Kooy Professor, Department of Molecular Genetics University of Toronto Topic: Where Brains Come From For more information, contact the MNN Office at (T) 235.3939 or email: mnn(a)sbrc.ca Presented in co-operation with University of Manitoba Clinical Neuroscience Rounds ------------------------------------------------------------- Edge of Science and Medicine Seminar Series | Dr. Detlev Boison Monday, February 25, 2013 Theatre B Basic Medical Sciences 12:00 - 1:00 PM Dr. Detlev Boison Interim Dow Chair of Neurology & Director of Neurobiology Research Director of Basic and Translational Research, Legacy Research Institute Adjunct Professor - Oregon Health & Science University, Portland, OR TOPIC: Therapeutic Epilepsy Research: Focus on Adenosine. ------------------------------------------------------------- Manitoba Neuroscience Network Seminar | Dr. X.-M. Li Date: Friday, March 22, 2013 Time: 9:00 am - 10:00 am Location: PZ236/238 PsychHealth Centre, Bannatyne Campus Dr. Xin-Min Li Professor, Department of Psychiatry University of Manitoba Topic: Depression: from clinical guidelines to neurobiology. ------------------------------------------------------------- Message from the Winnipeg Chapter of the Society for Neuroscience Please reserve MONDAY JUNE 10, 2013 for the 4th annual meeting of the Manitoba Neuroscience Network. The theme for 2013 will be "Neurodegeneration" and the meeting will be held jointly with the Manitoba-Ontario endMS Regional Research and Training Centre. The format will be similar to previous meetings, featuring: * Visiting expert speakers * Speakers showcasing local research * Networking opportunities * Poster session with trainee awards The official meeting and website announcement will follow early in 2013, with a MAY abstract deadline. Please plan on attending and thank you for making these meetings successful. Chris Anderson, Conference Chair Gilbert Kirouac, Program Committee Chair Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 Tel: 204.235.3939 Fax: 204.237.4092 Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca Website: www.sfn-manitoba.ca

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MNN Seminar - Feb 22 @ 12noon | Dr. Derek van der Kooy
by Winnipeg Chapter Society for Neuroscience 25 Jan '13

25 Jan '13

Manitoba Neuroscience Network Seminar Series Friday, February 22nd, 2013 | 12:00 noon Dr. Derek van der Kooy Professor Department of Molecular Genetics University of Toronto Topic: Where Brains Come From Location: Regenerative Medicine Lecture Theatre (626 BMSB) Derek van der Kooy served as Professor in the Department of Anatomy and Cell Biology at the University of Toronto from 1991 until 2002, when he became a Professor in the Department of Molecular Genetics. Derek received a M.Sc. in Psychology at the University of British Columbia, and a Ph.D in Anatomy, first at Erasmus University in the Netherlands, and finishing in the Department of Anatomy at the University of Toronto. Dr. van der Kooy gained postdoctoral research experience at Cambridge University in England and at the Salk Institute in California. The van der Kooy lab works on various stem cell biology and developmental biology research projects; specifically, stem cells in organisms from Drosophila to humans. We produced the first report of stem cells in the adult mammalian eye, published in 2000 in Science. We also have isolated a rare stem cell from the adult mouse and human pancreas that can show extensive proliferation under defined condi-tions in vitro. Of interest to the lab is the lineage of neural stem cells from pluripotent embryonic stem cells, with relevance to the origin of the earliest neural stem cell in the developing embryo. ABSTRACT: One of the few neurobiological facts not anticipated by Cajal is the existence of neural stem cells in the embryonic and adult mammalian brain that can produce new neurons in the adult brain (new neurons first shown by Altman). The earliest mammalian neural stem cells differentiate from pluripotent embryonic stem cells. These primitive neural stem cells emerge in response to LIF and have a wider non-neural phenotypic potential than later neural stem cells. By embryonic day 8.5 in mouse, true FGF2 dependent neural stem cells emerge and by embryonic day 14 they have given rise to copies of themselves and to EGF dependent neural stem cells. The separate FGF2 and EGF dependent neural stem cells increase greatly in numbers later in neurogenesis, but by E14 appear identical to adult neural stem cells. The adult mammalian neural stem cells are mostly quiescent, dividing asymmetrically only once every few weeks. Mouse embryonic stem (ES) cells cultured in low cell density, completely defined media adopt a neural identity. Using a clonal colony-forming assay, we identify the novel primitive neural stem cell stage as a component of neural lineage specification (this cell is similar to the one we isolate from the early embryo), which is negatively regulated by TGFb-related signaling. These results are consistent with a default mechanism for neural fate specification. Primitive neural stem cells are formed directly from single ES cells in a LIF-dependent manner, express multiple neural precursor markers and give rise to neurons and glia. Moreover, in vivo mouse chimera experiments reveal that these primitive ES-derived neural stem cells have a broad range of neural and non-neural lineage potential. These results support a model whereby definitive neural stem cell formation is preceded by a primitive neural stem cell stage during neural lineage commitment. Most recently, we have found that the LIF-dependent, primitive neural stem cells persist in adult organisms and can repopulate a depleted definitive neural stem cell pool in the adult. For more information, contact the MNN Office at (T) 235.3939 or email: mnn(a)sbrc.ca <mailto:mnn@sbrc.ca> Presented in co-operation with University of Manitoba Clinical Neuroscience Rounds Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 Tel: 204.235.3939 Fax: 204.237.4092 Email: kjorund(a)sbrc.ca OR kjorund(a)yahoo.ca Website: www.sfn-manitoba.ca

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