May 2017 - Neuro-All - University of Manitoba Mailing Lists

MNN abstract deadline TODAY
by Chris Anderson 29 May '17

29 May '17

Apologies if you have receive this before but some HSC subscribers are not receiving MNN emails consistently. We will fix this shortly and stop sending duplicates. One final reminder that the abstract deadline for the 2017 MNN Scientific Meeting is TODAY, May 29 @ 5:00 pm. Please view meeting information, register and submit abstracts at: https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/. Also a reminder that if you intend to register as a member of the Society for Neuroscience Winnipeg Chapter, you will need to become a 2017 member and create a membership account. If you have been a member in past years, you still must create a membership account for the 2017 membership year. You can do this and then register for the MNN meeting from your account at: https://manitobaneuroscience.ca/sfn-chapter-membership/become-a-sfn-chapter…. Chris Anderson MNN President Tabrez Siddiqui Chair, 2017 MNN Meeting

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MNN Abstract deadline TODAY @ 5 pm
by MNN Networking 29 May '17

29 May '17

One final reminder that the abstract deadline for the 2017 MNN Scientific Meeting is TODAY, May 29 @ 5:00 pm. Please view meeting information, register and submit abstracts at: https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/. Also a reminder that if you intend to register as a member of the Society for Neuroscience Winnipeg Chapter, you will need to become a 2017 member and create a membership account. If you have been a member in past years, you still must create a membership account for the 2017 membership year. You can do this and then register for the MNN meeting from your account at: https://manitobaneuroscience.ca/sfn-chapter-membership/become-a-sfn-chapter- member/. Thank you! MNN Team ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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Reminder - Tomorrow MNN Seminar: Dr. Mojgan Rastagar - Fri May 26th 9am
by Kelly Jorundson 25 May '17

25 May '17

S E M I N A R & V I S I T I N G S P E A K E R S E R I E S DATE: Friday, May 26th, 2017 TIME: 9:00 a.m. LOCATION: PX236/238 PsychHealth Building ***SPEAKER*** MOJGAN RASTEGAR, PH.D Associate Professor - Department of Biochemistry & Medical Genetics, Regenerative Medicine Program, University of Manitoba TOPIC: The bidirectional role of MeCP2 in the brain; a multi layer epigenetic deregulation in MeCP2-associated brain disorders ABSTRACT: Epigenetic mechanisms control gene expression and brain development without any direct change in the corresponding DNA sequences. Recent discoveries have highlighted the importance of epigenetic mechanisms in brain development, neuroscience, and mental health. MeCP2 is an important epigenetic factor in the brain with a bidirectional functional role that is controlled at multiple levels. While, MeCP2 loss-of-function mutations lead to Rett Syndrome (RTT), its gain-of-function genetic mutations cause MECP2 Duplication Syndrome (MDS) through gene duplication or triplication in the patients. RTT and MDS disorders have overlapping symptoms, and the patients show similar and severe neurological phenotypes that include mental disability, seizers, anxiety, and autism. It is well established that impaired protein translation is a characteristic of human RTT neurons. However, the underlying molecular mechanism of this phenotype is not fully understood. To study the underlying pathobiology of RTT and MDS, my lab investigates the bidirectional role of individual MeCP2 isoforms in controlling fundamental molecular pathways that regulate protein translation. We use a combination of primary neural stem cells, RTT and MDS mouse models, and post-mortem human RTT brain tissues to investigate how molecular deficiencies at the cellular levels lead to compromised brain function in RTT, MDS, and other MeCP2-associated brain disorders including autism. For more information contact: Eftekhar Eftekharpour Coordinator - MNN Seminar & Visiting Speaker Series 789-3214 eftekhar.eftekharpour(a)umanitoba.ca Sponsored by: Manitoba Neuroscience Network | Health Sciences Centre | University of Manitoba | St. Boniface Research Centre Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA

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MNN Scientific Meeting - Please submit ABSTRACTS and REGISTER
by Chris Anderson 25 May '17

25 May '17

Dear All, This is a reminder that the Manitoba Neuroscience Network (MNN) is holding its 7th Scientific Meeting June 16 at the Radisson Winnipeg. The 2017 meeting is chaired by Dr. Tabrez Siddiqui and he has assembled a stellar program that includes a featured lecture by one of leaders of the field of neural connectomics, Dr. Jeff Lichtman from Harvard University. Abstract submission and registration have been open for a couple of weeks. This year there have been several events that may interfere with timely abstract submission and we are seeing numbers that are lower than normal for this stage of the process. We are therefore EXTENDING the abstract deadline once more to MONDAY MAY 29 @ 5 pm. No further extensions will be possible after that because we will need to prepare the programs. As an extra incentive to submit, all trainee posters will be judged and there are several cash poster awards available. All MNN meeting attendees, including poster presenters, will need to register. The registration deadline is JUNE 5 @ 5 pm. Rates include coffee/snacks, full lunch and an afternoon reception with food. SFN Winnpeg Chapter members pay rates that are discounted by 50% so please become a member for 2017 before you register. PI's, you can purchase a membership for all of your lab members for one price, allowing each person to register for the MNN meeting as an SFN Chapter member. To LEARN ABOUT THE SFN WINNIPEG CHAPTER AND BECOME A MEMBER: click https://manitobaneuroscience.ca/sfn-chapter-membership/sfn-chapter-membersh… To VIEW MNN MEETING INFORMATION, SUBMIT YOUR ABSTRACT AND REGISTER: click https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/ Thank you for continuing to make the Manitoba Neuroscience Network a valuable and now award-winning networking and outreach hub! If you have any questions about using the new website for the MNN meeting of SFN Chapter membership, please let us know and we will find the answers. Sincerely, Chris Anderson, PhD MNN President chris.anderson(a)umanitoba.ca Tabrez J. Siddiqui, PhD Chair, 2017 MNN Scientific Meeting tabrez.siddiqui(a)umanitoba.ca

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Abstract deadline EXTENDED until Friday May 26 @ 5:00
by MNN Networking 23 May '17

23 May '17

We are pleased to announce that the abstract deadline for the 2017 MNN Scientific Meeting will be extended until FRIDAY MAY 26 at 5:00 pm. The original deadline (today) fell immediately after the May long weekend. We hope meeting delegates will find this extension to be useful. Please note that we will not be able to extend the deadline beyond Friday because a significant amount of time is required for processing and assembling the meeting program. Please submit your abstracts and register for the meeting at https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/ Thank you, The MNN Team ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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MNN Seminar: Dr. Mojgan Rastagar - Fri May 26th 9am
by Manitoba Neuroscience Network 19 May '17

19 May '17

cid:image001.jpg@01D158FE.B69B8D00 S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D AT E Friday, May 26th, 2017 9:00 a.m. LO C AT I O N PX236/238 PsychHealth Building Mojgan Rastegar, Ph.D. <http://rastegar.biochem.umanitoba.ca/> Associate Professor - Department of Biochemistry & Medical Genetics, Regenerative Medicine Program, University of Manitoba Topic: The bidirectional role of MeCP2 in the brain; a multi layer epigenetic deregulation in MeCP2-associated brain disorders ABSTRACT: Epigenetic mechanisms control gene expression and brain development without any direct change in the corresponding DNA sequences. Recent discoveries have highlighted the importance of epigenetic mechanisms in brain development, neuroscience, and mental health. MeCP2 is an important epigenetic factor in the brain with a bidirectional functional role that is controlled at multiple levels. While, MeCP2 loss-of-function mutations lead to Rett Syndrome (RTT), its gain-of-function genetic mutations cause MECP2 Duplication Syndrome (MDS) through gene duplication or triplication in the patients. RTT and MDS disorders have overlapping symptoms, and the patients show similar and severe neurological phenotypes that include mental disability, seizers, anxiety, and autism. It is well established that impaired protein translation is a characteristic of human RTT neurons. However, the underlying molecular mechanism of this phenotype is not fully understood. To study the underlying pathobiology of RTT and MDS, my lab investigates the bidirectional role of individual MeCP2 isoforms in controlling fundamental molecular pathways that regulate protein translation. We use a combination of primary neural stem cells, RTT and MDS mouse models, and post-mortem human RTT brain tissues to investigate how molecular deficiencies at the cellular levels lead to compromised brain function in RTT, MDS, and other MeCP2-associated brain disorders including autism. For more information contact: Eftekhar Eftekharpour Coordinator MNN Seminar & Visiting Speaker Series 789-3214 eftekhar.eftekharpour(a)umanitoba.ca Sponsored by: Manitoba Neuroscience Network | Health Sciences Centre | University of Manitoba | St. Boniface Research Centre Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies. ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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FW: MS Connect 2017 Research Event in Winnipeg
by Manitoba Neuroscience Network 19 May '17

19 May '17

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Dr. Soheila Karimi Subject: MS Connect 2017 Research Event in Winnipeg Hello I appreciate if you distribute the attached flyer and the note below on my behalf to MNN and Physiology. On May 23, 2017, the Multiple Sclerosis Society of Canada has organized an MS Connect 2017 Research Event in Winnipeg. This public event provides awareness on recent advances in MS Research. Dr. Wee Yong, a distinguished researcher in MS and Dr. Arsalan Alizadeh, a PhD candidate in Dr. Soheila Karimis laboratory, will present their research findings in this event. Please join them to learn more about MS research. This is the link to the event: https://mssociety.ca/library/image/oFBGA1HiC2rkphU3ELtwSPnz4gQXfTdD/large.jp g Thank you Soheila -- Soheila Karimi, PhD Associate Professor of Physiology and Pathophysiology Principal Investigator, Spinal Cord Injury and Stem Cell Program Senior Scientist, Regenerative Medicine Program Principal Investigator, Spinal Cord Research Center Rady Faculty of Health Sciences Max Rady College of Medicine University of Manitoba Lab Site: http://home.cc.umanitoba.ca/~karimis/ 745 Bannatyne Avenue, 629 BMSB Winnipeg, MB R3E 0J9 Canada Phone: (204) 272-3109 Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies. ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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****C A N C E L L E D **** TODAY MNN Visiting Speaker Dr. Long-Jun Wu - Fri. May 19
by Manitoba Neuroscience Network 19 May '17

19 May '17

*****C A N C E L L E D ***** Dr. Long-Jun Wu is not able to come to Winnipeg and therefore we have cancelled his research talk scheduled for today at 12noon. We are hopeful that Dr. Wu can reschedule his talk for later in the year. Apologies for any inconvenience. Kelly cid:image001.jpg@01D158FE.B69B8D00 S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D AT E Friday, May 19th, 2017 12:00 Noon LO C AT I O N Theatre C image008Long-Jun Wu, Ph.D. <http://www.mayo.edu/research/faculty/wu-longjun-long-jun-ph-d/bio-20305064> Associate Professor Department of Neurology, Mayo Medical School, Mayo Clinic Topic: Microglia-neuron communication in diseased brain (to be followed by a TRAINEE LUNCH in room SR415 **Please encourage all your neuroscience trainees to attend!) Microglia are the principal immune response cells in the central nervous system. Resting microglia constantly survey the microenvironment in the normal brain. Upon brain dysfunction, microglia are activated and exert detrimental or beneficial effects on the surrounding neurons. However, the molecular mechanisms for microglial activation and function in brain diseases are still controversial. The long-term goal of my lab is to understand microglia-neuron communication in the brain. We are interested in fundamental questions on: (1) How microglia sense neuronal activities? (2) How microglia regulate neuronal and synaptic function? (3) What are the molecular mechanisms and functional consequences of microglia activation in brain diseases? To address these questions, we use the combination of two photon deep-brain imaging, electrophysiology, mouse genetics to dissect the role of microglia in neuronal circuits and in brain disorders. These results provide a novel insight on microglial function in brain emostasis and suggest microglia as a potential therapeutic target for the treatment of brain diseases such as epilepsy, pain and stroke. For more information contact: Eftekhar Eftekharpour Coordinator MNN Seminar & Visiting Speaker Series 789-3214 eftekhar.eftekharpour(a)umanitoba.ca Sponsored by: Manitoba Neuroscience Network | Health Sciences Centre | University of Manitoba | St. Boniface Research Centre Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies. ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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Reminder ... TOMORROW MNN Visiting Speaker Dr. Long-Jun Wu - Fri. May 19
by Manitoba Neuroscience Network 18 May '17

18 May '17

cid:image001.jpg@01D158FE.B69B8D00 S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D AT E Friday, May 19th, 2017 12:00 Noon LO C AT I O N Theatre C image008Long-Jun Wu, Ph.D. <http://www.mayo.edu/research/faculty/wu-longjun-long-jun-ph-d/bio-20305064> Associate Professor Department of Neurology, Mayo Medical School, Mayo Clinic Topic: Microglia-neuron communication in diseased brain (to be followed by a TRAINEE LUNCH in room SR415 **Please encourage all your neuroscience trainees to attend!) Microglia are the principal immune response cells in the central nervous system. Resting microglia constantly survey the microenvironment in the normal brain. Upon brain dysfunction, microglia are activated and exert detrimental or beneficial effects on the surrounding neurons. However, the molecular mechanisms for microglial activation and function in brain diseases are still controversial. The long-term goal of my lab is to understand microglia-neuron communication in the brain. We are interested in fundamental questions on: (1) How microglia sense neuronal activities? (2) How microglia regulate neuronal and synaptic function? (3) What are the molecular mechanisms and functional consequences of microglia activation in brain diseases? To address these questions, we use the combination of two photon deep-brain imaging, electrophysiology, mouse genetics to dissect the role of microglia in neuronal circuits and in brain disorders. These results provide a novel insight on microglial function in brain emostasis and suggest microglia as a potential therapeutic target for the treatment of brain diseases such as epilepsy, pain and stroke. For more information contact: Eftekhar Eftekharpour Coordinator MNN Seminar & Visiting Speaker Series 789-3214 eftekhar.eftekharpour(a)umanitoba.ca Sponsored by: Manitoba Neuroscience Network | Health Sciences Centre | University of Manitoba | St. Boniface Research Centre Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies. ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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MNN abstract deadline in 8 days (MAY 23)
by MNN Networking 15 May '17

15 May '17

This is a reminder that registration and abstract submission for the upcoming MNN Scientific Meeting are open. The meeting website, including program information, is available at https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/. The abstract deadline is MAY 23 @ 5:00 pm and you can submit directly at https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/ab stract-submissions/. Contact mnn2017(a)manitobaneuroscience.ca <mailto:mnn2017@manitobaneuroscience.ca> for questions. You must be registered for the meeting to attend and present your abstract. You may register until JUNE 5 at https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/re gistration/. You will receive 50% off the regular registration rate if you are a 2017 SFN Winnipeg Chapter member. You can receive this benefit and take a valuable, active role in neuroscience networking, outreach and education in Manitoba by visiting https://manitobaneuroscience.ca/sfn-chapter-membership/become-a-sfn-chapter- member/. Contact membership(a)manitobaneuroscience.ca <mailto:membership@manitobaneuroscience.ca> for membership questions. Thank you! The MNN Team ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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Reminder: MNN Visiting Speaker Dr. Long-Jun Wu - Fri. May 19
by Manitoba Neuroscience Network 15 May '17

15 May '17

cid:image001.jpg@01D158FE.B69B8D00 S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D AT E Friday, May 19th, 2017 12:00 Noon LO C AT I O N Theatre C image008Long-Jun Wu, Ph.D. <http://www.mayo.edu/research/faculty/wu-longjun-long-jun-ph-d/bio-20305064> Associate Professor Department of Neurology, Mayo Medical School, Mayo Clinic Topic: Microglia-neuron communication in diseased brain (to be followed by a TRAINEE LUNCH in room SR415 **Please encourage all your neuroscience trainees to attend!) Microglia are the principal immune response cells in the central nervous system. Resting microglia constantly survey the microenvironment in the normal brain. Upon brain dysfunction, microglia are activated and exert detrimental or beneficial effects on the surrounding neurons. However, the molecular mechanisms for microglial activation and function in brain diseases are still controversial. The long-term goal of my lab is to understand microglia-neuron communication in the brain. We are interested in fundamental questions on: (1) How microglia sense neuronal activities? (2) How microglia regulate neuronal and synaptic function? (3) What are the molecular mechanisms and functional consequences of microglia activation in brain diseases? To address these questions, we use the combination of two photon deep-brain imaging, electrophysiology, mouse genetics to dissect the role of microglia in neuronal circuits and in brain disorders. These results provide a novel insight on microglial function in brain emostasis and suggest microglia as a potential therapeutic target for the treatment of brain diseases such as epilepsy, pain and stroke. For more information contact: Eftekhar Eftekharpour Coordinator - MNN Seminar & Visiting Speaker Series 789-3214 eftekhar.eftekharpour(a)umanitoba.ca Sponsored by: Manitoba Neuroscience Network | Health Sciences Centre | University of Manitoba | St. Boniface Research Centre

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Nick Shepel Trainee Travel Award - Deadline June 30th
by Kelly Jorundson 11 May '17

11 May '17

Nick Shepel Neuroscience Trainee Travel Award Application deadline: June 30th, 2017 The fund was established by the Division of Neurodegenerative Disorders, St. Boniface Hospital Research Centre, to honor Nick Shepel who was an outstanding researcher, friend and leader. Nick was a true inspiration to his laboratory partners and brought fire, humor, and a desire to always excel. His insistence to always try better has had a permanent effect on his lab mates and peers. Nick led by example and taught that detailed preparation and execution of experiments ensured reliable results. Purpose: The purpose of this fund shall be to recognize a young investigator (specifically in the neuroscience area) by providing an annual award(s) to support travel costs associated with the applicant's attendance at an upcoming national/international conference where the applicant is presenting a poster or oral presentation. This year, the value of the award may range from $300-600. Eligibility: At the time of application - · Students must be registered as a full-time graduate student at a Manitoba university. · A student admitted under the "Provisional Status" may not receive the award during the provisional period. · Amount of award(s) may vary each year. · Students must be giving a poster or oral presentation at an upcoming scientific meeting (national/international) Submission Instructions: A complete application consists of the following: · Introductory letter describing meeting · Copy of abstract · Curriculum vitae · Current GPA, transcripts not needed · Proposed budget of travel costs · Submit your completed application materials to: Paul Fernyhough Director - Division of Neurodegenerative Disorders St. Boniface Hospital Research R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6 How to apply for reimbursement: Reimbursement will be done in accordance with St. Boniface Hospital travel policies. Only original receipts will be accepted. Copies may be accepted only where proof of submission to another agency is provided. Kelly Jorundson Administrative Manager, Division of Neurodegenerative Disorders St. Boniface Hospital Research Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies.

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MNN Website and Scientific Meeting - CALL FOR ABSTRACTS AND REGISTRATION
by MNN Networking 03 May '17

03 May '17

We are excited to launch PHASE 1 of the new MNN website, now live at www.manitobaneuroscience.ca <http://www.manitobaneuroscience.ca> ! At rollout, the main purpose of the site is to serve as a SFN Winnipeg Chapter membership hub and an information, abstract and registration portal for the upcoming MNN Scientific Meeting. There is limited content now but much more is to follow in PHASE 2. SFN WINNIPEG CHAPTER MEMBERSHIPS: As always, if you are a SFN Winnipeg Chapter member, you are making a valuable contribution to neuroscience networking, outreach and education in Manitoba AND you receive dramatically discounted registration rates for the MNN Scientific Meeting. All 2016 memberships expired on December 31, 2016 and we paused intake of 2017 memberships pending completion of the new website. Starting today, you may purchase a 2017 SFN Chapter membership on the new website by visiting: https://manitobaneuroscience.ca/sfn-chapter-membership/become-a-sfn-chapter- member/. The new link will allow members to create a secure membership account that can be used to manage your membership AND access the member's only MNN meeting registration pricing. You may pay by credit/debit card of University of Manitoba FOP. By popular demand, we are continuing to offer a laboratory all-inclusive membership, in addition to individual memberships. This membership type can be selected by Principal Investigators in the "Regular" Membership category. He or she will be asked to enter each lab member included in the membership. Each person entered will receive an email with a pre-paid lab code that can be used to complete an individual membership account at no cost. PI's will be able to add or delete members at any time by accessing their membership account. MEMBERSHIP inquiries should be sent to membership(a)manitobaneuroscience.ca <mailto:membership@manitobaneuroscience.ca> MNN SCIENTIFIC MEETING: The Scientific Meeting will be held JUNE 16 and is being chaired by Dr. Tabrez Siddiqui. He's planned a fabulous program featuring a visit and talk by Dr. Jeff Lichtman from Harvard University. The website, including current program, is live at https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/. Abstracts and registrations are now being accepted. This will be a narrower abstract submission and registration period than in previous years. We apologize for that. Nevertheless, there are still almost 3 weeks until the abstract deadline (MAY 23) and longer until the registration deadline (JUNE 5). We encourage you to visit the site now to submit your abstracts and register for the meeting. SFN Chapter member rates are half those of non-member rates so consider becoming a member first. You may pay by credit card or by University of Manitoba FOP. If you pay by FOP, you will be registered for the meeting immediately but your payment will be pending. Once the FOP payment is processed, you will receive a receipt and confirmation by email. MNN Scientific Meeting inquiries should be sent to mnn2017(a)manitobaneuroscience.ca <mailto:mnn2017@manitobaneuroscience.ca> Finally, any SFN Chapter members who have already renewed for 2017 (there are only a handful at this point) will be contacted with instructions for migration to the new system. Phase 2 of the website will debut soon with a rich array of content, including the ability for principal investigators to create and manage a scientific profile that showcases the depth and breadth of Manitoba neuroscience research to the world. Thank you for your patience. -The MNN Team ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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MNN Visiting Speaker - Friday May 5 @ 12NOON
by Manitoba Neuroscience Network 03 May '17

03 May '17

cid:image001.jpg@01D158FE.B69B8D00 S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D AT E Friday, May 5th, 2017 12:00 Noon LO C AT I O N Apotex 071 W. Dalton Dietrich, PhD <http://www.themiamiproject.org/research/faculty/dalton-dietrich/> Scientific Director, The Miami Project to Cure Paralysis Departments of Neurological Surgery, Neurology and Biomedical Engineering, University of Miami Miller School of Medicine, Miami Topic: New Insights into the Pathophysiology and Treatment of Spinal Cord Injury: Current and Future Directions (to be followed by a TRAINEE LUNCH in room SR415 **Please encourage all your neuroscience trainees to attend!) W. Dalton Dietrich, Ph.D., Scientific Director, The Miami Project to Cure Paralysis, Departments of Neurological Surgery, Neurology and Biomedical Engineering, University of Miami Miller School of Medicine, Miami FL USA Each year thousands of new spinal cord injuries (SCI) occur throughout the world leading to long-term deficits and serious quality of life issues. Currently, there are millions of people living with the detrimental consequences of SCI that could benefit from reparative strategies to enhance ability and function. Although a large number of exciting preclinical studies have been conducted to test therapeutic interventions, to date no proven therapeutic modality exists that has been demonstrated to significantly improve neurological outcome. This fact emphases the need for continued research on the pathophysiology and treatment of this serious clinical condition. In the area of neuroprotection, our research programs have focused on the beneficial effects of therapeutic hypothermia on reducing multiple secondary injury mechanisms and improving outcomes. Studies conducted in multiple laboratories have now reported that mild reductions in core or spinal cord temperature early after SCI reduce overall histopathological damage and improves long-term functional outcomes. Recently, we have been successful in translating this experimental therapy to severely injured cervical SCI patients using a well described cooling and rewarming strategy. To date, we have cooled over 60 AIS A patients and at 1 year, over 43 percent of patients have converted to incomplete status (AIS B, C). A new randomized multicenter trial to assess the long-term beneficial effects of therapeutic hypothermia on sensory and motor function is now underway. In addition to acute protection, work has also emphasized the use of cell therapies and rehabilitation to improve outcomes by replacing damaged cells or producing a more permissive environment for axonal repair. We have studied the beneficial effects of autologous Schwann cell transplantation in multiple models of SCI. Schwann cell transplantation enhances axonal remyelination, growth promoting factor production and axonal regeneration. We have submitted an IND to the FDA and obtained permission to test autologous human Schwann cell transplantation in SCI. We have completed a dose escalation safety study in subacute patients with severe thoracic SCI. Based on encouraging data, we are now recruiting and transplanting Schwann cells into chronically injured spinal cord subjects that have undergone extensive rehabilitation. In addition, the benefits of neural modulation including transcranial magnetic stimulation that may act synergistically with other treatments are being assessed. Discovery and translational studies continue to provide new knowledge to fuel our future clinical studies and trials. This presentation will review progress in these areas of SCI research and other related topics.

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