- Neuro-All - University of Manitoba Mailing Lists

Reminder: Tomorrow - Jeremy Chopek | Fri Nov 30 @ 9am
by Manitoba Neuroscience Network 29 Nov '18

29 Nov '18

cid:image001.jpg@01D158FE.B69B8D00 M N N S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D A T E Friday, November 30th, 2018 9am L O C A T I O N: Px236/238 PsycHealth Bldg. Bannatyne Campus S P E A K E R Dr. Jeremy Chopek Assistant Professor Physiology & Pathophysiology Rady Faculty of Health Sciences T O P I C Investigating brainstem and spinal cord movement circuits using mouse genetics O B J E C T I V E S 1) Understand the utility of mouse genetic for examining movement 2) Appreciate the complexity of local cellular connectivity 3) Understand the role of the brainstem and spinal cord in producing movement B I O S K E T C H: Dr. Jeremy Chopek received his Msc (2009) in Kinesiology and PhD (2014) in the Department of Physiology, University of Manitoba under the supervision of Dr. Phillip Gardiner, in the Spinal Cord Research Centre. His work examined how motor circuits were affected following spinal cord injury and exercise by examining alterations in motoneuron biophysical properties, stretch reflexes, gene expression and sensitivity to pharmacological agents. Afterwards, Jeremy completed a post-doctoral position at Dalhousie University (2014-2017) and University College London (2017-2018) working with both Dr. Zhang and Dr. Brownstone. His work has focused on microcircuit formation in both the medulla reticular formation and lumbar spinal cord, centres that are vital for the initiation and execution of movement. To achieve this, he uses a combination of transgenic mouse lines, optogenetic or photo-manipulation of single cell or whole cell populations, in-vitro electrophysiology, viral tracers and confocal microscopy. To date, he has subdivided the chx10 neuronal population in the brainstem into two distinct cell populations based on their morphology, biophysical properties, connectivity and projection patterns. In addition, he has also found a novel connectivity pattern of the spinal V3 interneuron population, which in addition to forming commissural connections also synapse locally with ipsilateral motoneurons. For more information, contact the MNN office @ 204.235.3939 Tabrez Siddiqui Chair, MNN Seminar Series E: Tabrez.siddiqui(a)umanitoba.ca Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 . ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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MNN Seminar: Jeremy Chopek | Fri Nov 30 @ 9am
by Manitoba Neuroscience Network 26 Nov '18

26 Nov '18

cid:image001.jpg@01D158FE.B69B8D00 M N N S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D A T E Friday, November 30th, 2018 9am L O C A T I O N: Px236/238 PsycHealth Bldg. Bannatyne Campus S P E A K E R Dr. Jeremy Chopek Assistant Professor Physiology & Pathophysiology Rady Faculty of Health Sciences T O P I C Investigating brainstem and spinal cord movement circuits using mouse genetics O B J E C T I V E S 1) Understand the utility of mouse genetic for examining movement 2) Appreciate the complexity of local cellular connectivity 3) Understand the role of the brainstem and spinal cord in producing movement B I O S K E T C H: Dr. Jeremy Chopek received his Msc (2009) in Kinesiology and PhD (2014) in the Department of Physiology, University of Manitoba under the supervision of Dr. Phillip Gardiner, in the Spinal Cord Research Centre. His work examined how motor circuits were affected following spinal cord injury and exercise by examining alterations in motoneuron biophysical properties, stretch reflexes, gene expression and sensitivity to pharmacological agents. Afterwards, Jeremy completed a post-doctoral position at Dalhousie University (2014-2017) and University College London (2017-2018) working with both Dr. Zhang and Dr. Brownstone. His work has focused on microcircuit formation in both the medulla reticular formation and lumbar spinal cord, centres that are vital for the initiation and execution of movement. To achieve this, he uses a combination of transgenic mouse lines, optogenetic or photo-manipulation of single cell or whole cell populations, in-vitro electrophysiology, viral tracers and confocal microscopy. To date, he has subdivided the chx10 neuronal population in the brainstem into two distinct cell populations based on their morphology, biophysical properties, connectivity and projection patterns. In addition, he has also found a novel connectivity pattern of the spinal V3 interneuron population, which in addition to forming commissural connections also synapse locally with ipsilateral motoneurons. For more information, contact the MNN office @ 204.235.3939 Tabrez Siddiqui Chair, MNN Seminar Series E: Tabrez.siddiqui(a)umanitoba.ca Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA Email: <mailto:kjorund@sbrc.ca> kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 . ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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Dementia Journal club - Presentation on Nov 29th noon at HSC - Dr Puig
by Manitoba Neuroscience Network 21 Nov '18

21 Nov '18

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Ben Albensi Dementia Journal club - Dr Josep Puig DATE: NOV 29TH, 2018 TIME: 12 PM - NOON LOCATION: UNIV MANITOBA - HEALTH SCI CTR., GG147 Topic: Aging Imageomics Study: Looking at imaging, seeing health See attached poster for upcoming presentation. For more information please contact: Ben Albensi balbensi(a)sbrc.ca Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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Reminder TODAY: Dr. Wei Lu | Lecture @ 12 noon Theatre C
by Manitoba Neuroscience Network 15 Nov '18

15 Nov '18

cid:image001.jpg@01D158FE.B69B8D00 M N N S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D A T E: Thursday November 15th, 2018 12:00 Noon L O C A T I O N: Theatre C Bannatyne Campus **followed by a trainee lunch in SR415 Kleysen Bldg. S P E A K E R Dr. Wei Lu Synapse and Neural Circuit Section Porter Neuroscience Research Center National Institute of Neurological Disorders and Stroke National Institutes of Health T O P I C: Making the brains own brake | Molecular mechanisms of inhibitory synapse development. O b j e c t I v e s: Discuss the recent progress from my lab in understanding the molecular and cellular mechanisms for inhibitory synapse development B I O S K E T C H: Ph.D. (Neuroscience and Physiology). Laboratory of Edward Ziff, New York University School of Medicine, New York, 2006 M.S. (Molecular Biology/Entomology). Zhejiang University, China, 2000 B.S. (Biochemistry). Sichuan University, China, 1997 Recent publications: Steinkellner Thomas, Zell Vivien, Farino Zachary, Sonders Mark, Villeneuve Michael, Freyberg Robin, Przedborski Serge, Lu W, Freyberg Zachary, Hnasko Thomas (2018): Role for VGLUT2 in selective vulnerability of midbrain dopamine neurons. The Journal of Clinical Investigation. 128 (2) Gu XL, Lu W (2018) Genetic deletion of NMDA receptors suppresses GABAergic synaptic transmission in two distinct types of central neurons. Neuroscience Letters. 668, 147-153. Hutchison MA, Gu X, Adrover MF, Lee MR, Hnasko TS, Alvarez VA and Lu W (2018) Genetic inhibition of neurotransmission reveals role of glutamatergic input to dopamine neurons in high-effort behavior. Molecular Psychiatry. 23, 1213-1225. Yeh CY, Asrican B, Moss J, Quintanilla LJ, He T, Mao X, Casse F, Gebara E, Bao HC, Lu W, Toni N, Song J (2018) Mossy Cells Control Adult Neural Stem Cell Quiescence and Maintenance through a Dynamic Balance between Direct and Indirect Pathways. Neuron. 99(3):493-510 For more information, contact the MNN office @ 204.235.3939 Tabrez Siddiqui Chair, MNN Seminar Series E: Tabrez.siddiqui(a)umanitoba.ca Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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MNN Visiting Speaker - Dr. Wei Lu | Thursday Nov 15th @ 12 noon Theatre C
by Manitoba Neuroscience Network 13 Nov '18

13 Nov '18

cid:image001.jpg@01D158FE.B69B8D00 M N N S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D A T E: Thursday November 15th, 2018 12:00 Noon L O C A T I O N: Theatre C Bannatyne Campus **followed by a trainee lunch in SR415 Kleysen Bldg. S P E A K E R Dr. Wei Lu Synapse and Neural Circuit Section Porter Neuroscience Research Center National Institute of Neurological Disorders and Stroke National Institutes of Health T O P I C: Making the brains own brake | Molecular mechanisms of inhibitory synapse development. O b j e c t I v e s: Discuss the recent progress from my lab in understanding the molecular and cellular mechanisms for inhibitory synapse development B I O S K E T C H: Ph.D. (Neuroscience and Physiology). Laboratory of Edward Ziff, New York University School of Medicine, New York, 2006 M.S. (Molecular Biology/Entomology). Zhejiang University, China, 2000 B.S. (Biochemistry). Sichuan University, China, 1997 Recent publications: Steinkellner Thomas, Zell Vivien, Farino Zachary, Sonders Mark, Villeneuve Michael, Freyberg Robin, Przedborski Serge, Lu W, Freyberg Zachary, Hnasko Thomas (2018): Role for VGLUT2 in selective vulnerability of midbrain dopamine neurons. The Journal of Clinical Investigation. 128 (2) Gu XL, Lu W (2018) Genetic deletion of NMDA receptors suppresses GABAergic synaptic transmission in two distinct types of central neurons. Neuroscience Letters. 668, 147-153. Hutchison MA, Gu X, Adrover MF, Lee MR, Hnasko TS, Alvarez VA and Lu W (2018) Genetic inhibition of neurotransmission reveals role of glutamatergic input to dopamine neurons in high-effort behavior. Molecular Psychiatry. 23, 1213-1225. Yeh CY, Asrican B, Moss J, Quintanilla LJ, He T, Mao X, Casse F, Gebara E, Bao HC, Lu W, Toni N, Song J (2018) Mossy Cells Control Adult Neural Stem Cell Quiescence and Maintenance through a Dynamic Balance between Direct and Indirect Pathways. Neuron. 99(3):493-510 For more information, contact the MNN office @ 204.235.3939 Tabrez Siddiqui Chair, MNN Seminar Series E: Tabrez.siddiqui(a)umanitoba.ca Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: <mailto:kjorund@sbrc.ca> kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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Reminder: New Winter Term 2019 Neuroscience Graduate Courses
by Manitoba Neuroscience Network 07 Nov '18

07 Nov '18

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Brent Fedirchuk Greetings Manitoba Neuroscience Community, You may recall that back in the summer, a notice was sent out that the "Fundamental Neuroscience" graduate courses (IMED7101 & IMED7102) have been replaced with a suite of 4 separate 1.5 credit hour courses. The first 2 of these new courses (IMED7112 and IMED7114) have been offered during the Fall 2018 semester. I wanted to remind you that the next two 1.5 credit hour courses will be offered in the upcoming Winter 2019 session (Jan - Apr 2019). They are: "IMED7116 - Fundamental Systems Neuroscience" (Jan - Feb 2019) and "IMED7118 - Fundamental Neurobiology of Disease" (Mar - Apr 2019) Please see the attached notice for more information (and please print it / post it to help make sure all prospective students know about it!). Feel free to contact either me (for IMED7116) or Dr. Marc Del Bigio marc.delbigio(a)umanitoba.ca (for IMED7118) for additional information. Thanks, Brent ====================================== Brent Fedirchuk, Ph.D. Associate Professor Department of Physiology and Pathophysiology Max Rady College of Medicine Rady Faculty of Health Sciences University of Manitoba 745 Bannatyne Avenue; Rm 410 BMSB Winnipeg, MB R3E 0J9 CANADA tel (204) 789-3762 (sorry, no voice mail) fax (204) 789-3934 <http://www.scrc.umanitoba.ca/> www.scrc.umanitoba.ca ======================================

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SCRC Journal Club 2018-19 schedule
by Manitoba Neuroscience Network 24 Oct '18

24 Oct '18

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Katinka Stecina Katinka.stecina(a)umanitoba.ca Everyone is invited! Hello all, In continuation of our SCRC Journal Club seminar series this year we will resume our weekly meetings on Friday November the 9th, 2018. Kindly find attached the schedule for the 2018-2019 SCRC Journal club series. You will notice we will have some invited speakers in addition to trainees. Please note our new time and location - 11am to noon on Fridays in room 405 of Brodie Centre. In our view the main objectives of having a journal club are: 1. Develop and hone critical thinking skills. 2. Develop a breadth of knowledge in the sciences related to spinal cord injury. 3. Creating a platform for the trainees and PIs to interact and get to know some possible collaborators. To meet these objectives and increase the possibility of interaction we are tweaking the format: The presentation should be about a recent journal article or more, relevant to the students' project. When presenting a paper questions that can be addressed by the student: a. Why this paper is of interest? b. What did this paper add to the field? c. What are the shortcomings of the work? d. What can be done differently or be the next step from this paper? e. The presenter can use the paper to segue into their own data and techniques. The journal club may be used to present data if the need arises such as to get feedback on the direction of the trainee's work or alternative understanding of their results. It is expected of each trainee to be prepared to present in their allotted time. In case of unavoidable circumstances, trainees can arrange to switch their scheduled talks with another presenter and inform me of any changes as soon as possible. Best regards, Mona Nazzal and Katinka Stecina

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Tomorrow: Thursday, October 25th SCRC Visiting Scientist Lecture by Dr. David Ditor
by Manitoba Neuroscience Network 24 Oct '18

24 Oct '18

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Dr. Phillip Gardiner Spinal Cord Research Centre Visiting Scientist Lecture David S. Ditor, Ph.D. Professor, Department of Kinesiology Director, POWER CORD - Accessible Exercise Brock University Targeting inflammation as a means to manage neuropathic pain and depression after spinal cord injury. Thursday, October 25, 2018 1:30-2:30pm Physiology Seminar Room 431, BMSB 745 Bannatyne Avenue All are welcome to attend. Notice attached. Dr. Ditor's website <https://brocku.ca/applied-health-sciences/kinesiology/faculty-research/facu lty-directory/david-ditor-phd/> For further information, contact Dr. Phillip Gardiner, 204-977-5622 Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: <mailto:kjorund@sbrc.ca> kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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****CANCELLED*** MNN Lecture | Dr. L. Jordan - Friday Oct. 26th 9am
by Manitoba Neuroscience Network 22 Oct '18

22 Oct '18

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Dr. Tabrez Siddiqui Please note that the MNN lecture scheduled for this Friday Oct 26th has been cancelled. Apologies for the inconvenience. Regards, Tabrez ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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Tomorrow 12 noon | Gairdner Lecture | Presenter Karl Deisseroth
by Manitoba Neuroscience Network 22 Oct '18

22 Oct '18

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Chris Anderson Everyone is invited! ANNUAL GAIRDNER LECTURE DISCOVERY OF OPTOGENETICS AND DEVELOPMENT OF CAUSAL SYSTEMS NEUROSCIENCE TUESDAY, OCTOBER 23 12:00 PM Frederic Gaspard Theatre Basic Medical Sciences Bldg 745 Bannatyne Ave. Bannatyne Campus Presented by Karl Deisseroth, MD, PhD RECIPIENT OF THE CANADA GAIRDNER INTERNATIONAL AWARD (2018) D. H. Chen D. H. Chen Professor of Bioengineering and of Psychiatry and Behavioral Sciences, Stanford University; Investigator, Howard Hughes Medical Institute Dr. Deisseroth is the D. H. Chen Professor of Bioengineering and of Psychiatry and Behavioral Sciences at Stanford University. He is known for creating and developing the technologies of CLARITY and optogenetics, and for applying integrated optical and genetic strategies to study normal neural circuit function as well as dysfunction in neurological and psychiatric disease. He has led the Deisseroth laboratory since 2004. Based in the James H. Clark Center at Stanford, the lab employs a range of techniques including neural stem cell and tissue engineering methods, electrophysiology, molecular biology, neural activity imaging, animal behavior, and computational neural network modeling. Dr. Deisseroth serves as an attending physician at Stanford Hospital and Clinics, and has been affiliated with the Howard Hughes Medical Institute since 2009. Since 2014 he is a foreign Adjunct Professor at Swedens prestigious Karolinska medical institute. Presentation will be live streamed on http://umanitoba.ca/medicine Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: <mailto:kjorund@sbrc.ca> kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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