- Neuro-All - University of Manitoba Mailing Lists

MNN Visiting Speaker - Dr. J. Geiger | Sept 21 @ 12 noon
by Manitoba Neuroscience Network 28 Aug '18

28 Aug '18

cid:image001.jpg@01D158FE.B69B8D00 S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D AT E Friday, September 21st, 2018 12:00 Noon LO C AT I O N Theatre C Bannatyne Campus S P E A K E R Jonathan Geiger, Ph.D. <https://und.edu/directory/jonathan.geiger> Chester Fritz Distinguished Professor UND School of Medicine and Health Sciences Department of Basic Biomedical Sciences T O P I C An ‘iron-ic’ story about endolysosomes, inter-organellar signaling and neurodegenerative diseases O B J E C T I V E S 1. Appreciate that endolysosomes contain readily releasable stores of cations including iron and calcium. 2. Discuss specific examples of inter-organellar signaling. 3. Know that de-acification of endolysosomes profoundly affects endolysosome structure, distribution and function. 4. Appreciate that endolysosome pH and cation release from endolysosomes are early and upstream events central to the pathogenesis of neurodegenerative diseases including HIV-1 associated neurocognitive disorder and Alzheimer’s disease. B I O S K E T C H After two years as a postdoctoral fellow at the University of Manitoba (’ 82-’84), I accepted a faculty position in the Department of Pharmacology and Therapeutics at the University of Manitoba where I remained for 19 years (‘84-‘03) rising to the rank of Professor and Founding Director (‘99- ‘03) of the Division of Neurovirology and Neurodegenerative Diseases at the St. Boniface General Hospital Research Centre. From July 2003 to July 2013 I served as Chair of the UND Department of Pharmacology, Physiology and Therapeutics. From July 2003 to present I continue to serve as Principal Investigator on our NIGMS-funded neuroscience center grant. In addition, from July 2010 to July 2013 I served as Interim Chair of the Department of Anatomy and Cell Biology. I have consistently held multiple federal operating grants simultaneously throughout my career, and I received highly prestigious Scholarship and Scientist awards (separate grants that pay an investigator’s salary independent of research operating grants) from the Canadian Institutes of Health Research. I am currently funded by one P30 NIGMS grant, two five-year R01 NIMH grants, one R21 NIDA grant, and hold the position of Chester Fritz Distinguished Professor. The main focus of my research continues to be on brain energy metabolism in general and purines in particular, regulation of levels of intracellular calcium with emphasis on intracellular pools of calcium, the control of neuronal cell life and death in neurodegenerative diseases, and neurological complications associated with HIV-1 infection. Currently, my laboratory has the following research interests: (1) The role of brain energy metabolism (with particular emphasis on adenosine and ATP) in the pathogenesis of epilepsy and neurodegenerative diseases and the ability of ketogenic diets to protect against these pathophysiological responses; (2) The role of endolysosome dysfunction in animals models of Alzheimer’s disease and HIV-1 associated neurocognitive disorder; (3) The protective actions of caffeine in animal models of neurodegenerative disorders; and (4) The ability of calcium in endolysosomes to influence capacitative influx of calcium and calcium-induced calcium release. I have published over 150 manuscripts and have delivered over 100 invited talks worldwide. I have served on over 120 local, national and international grant review study sections including those for the NIH (I am currently serving a 6-year term as a standing member of the NAED study section) and I have served as Chair or co-Chair on over 20 of these panels. I am now serving as Chair of the NAED study section for the next 2 years. I have extensive mentoring experience. Since 2000, as a Director or Department Chair I hired 11 new faculty members. I have graduated seven Ph.D. and four M.S. students from my laboratory and trained 17 postdoctoral fellows, research associates and visiting professors as well as 48 undergraduate students, medical and dental students, and technicians. I have also served on and been President of major advisory boards as well as on many high level committees for UND. I currently serve on advisory boards for two COBRE grants, and I serve on the North Dakota EPSCoR Steering Committee. My publications have been cited over 5,500 times of which about 200 are self-citations. I have published 15 manuscripts that have been cited greater than 80 times and 10 manuscripts have been cited greater than 100 times. My h-index (Scopus) is 45. I am President of the Society of NeuroImmune Pharmacology and serve on the scientific meeting organizing committee for the American Society of Neurochemistry. Complete Bibliography http://www.ncbi.nlm.nih.gov/pubmed/?term=geiger+JD+NOT+(surgery+OR+pediatric ) Recent publications (selected from 30 publications from the past 5 years): 1. Hui, L., Chen, X., Bhatt, D., Rosenberg, T.A., Haughey, N.J., Masino, S. and <file:///C:\Users\debra.kroese\Documents\Geiger%20Documents\Publications\201 2\Hui%20et%20al.,%20J.%20of%20Neurochem%20122.pdf> J.D. Geiger. (2012) Ketone Bodies Protection Against HIV-1 Tat Neurotoxicity. J. Neurochem. 122: 382-391. 2. Bae, M., Patel, N. Xu, H., Lee, M., Nath, A., Geiger, J.D., Gorospe, M.M., Mattson, M.P., and Haughey, N.J. (2014) Activation of TRPML1 Clears Intraneuronal Aβ in Pre-Clinical Models of HIV-Infection. J. Neurosci. 34 (34): 11485-11503. 3. Stevens, P.R., Ramonet, D., Gawryluk, J.W., Buscemi, L., and J.D. Geiger. (2015) Mitochondrial Mechanisms Responsible for Creatine Protection against HIV-1 Tat-Induced Neurotoxicity. Current HIV Research 12: 378-387. 4. Hui, L., Geiger, N.H., Bloor-Young, D., Churchill, G.C., Geiger, J.D., and X. Chen (2015) Release of Calcium from Endolysosomes Increases Calcium Influx Through N-Type Calcium Channels: Evidence for Acidic Store-Operated Calcium Entry in Neurons. Cell Calcium 58(6): 617-627. /sent on behalf of Tabrez Siddiqui Chair, Seminar Series Manitoba Neuroscience Network E: Tabrez.siddiqui(a)umanitoba.ca Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies. ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326. 7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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Rebecca Kamen - workshop, lecture, and meetings on September 24th
by outreach＠manitobaneuroscience.ca 20 Aug '18

20 Aug '18

cid:image001.jpg@01D158FE.B69B8D00 Hello everyone, I hope your summer has been equal parts relaxing and productive. As we look ahead to September, the MNN has planned an exciting event to kick off the academic year. Award-winning artist Rebecca Kamen will be visiting the University of Manitoba as a guest of the Faculty of Science, and on September 24th, she has graciously agreed to spend the day at the Bannatyne campus interacting with neuroscience researchers and students. As you will read below, Rebecca has a longstanding interest in neuroscience and she has participated in projects at Harvard, MIT, NIH, and the Cajal Institute. You can learn more about Rebecca and her work by visiting her website: https://rebeccakamen.com/#1 We have planned three events that are open to neuroscience faculty, staff, and students: 1. Sculpture workshop: 9-11:30 am. Rebecca will lead a workshop in which the participants will work together to model scientific concepts such as synapses and ion channels. Please see the attached outline for details. The workshop is free and no experience is necessary. Individuals and groups are welcome to sign up. Faculty members, please take note that this could be a valuable team-building/brainstorming exercise for your lab. Please RSVP to this email address to reserve your spot (include all names if you are replying on behalf of a group). 2. Lecture: 12-1 pm, Theatre B. Rebecca will present a lecture focusing on her work and her experiences at the Cajal Institute, where she had the opportunity to study Cajal's original drawings. She has indicated that she would like to meet as many neuroscientists as possible during her visit, and to facilitate this, we have planned a free lunch reception that will take place on the Joe Doupe Concourse immediately after the lecture. 3. Meetings with individual researchers. Rebecca will be available for one-on-one meetings in the afternoon. She is very interested in the cellular/molecular basis of curiosity, cognition, decision making, memory, and networks related to visual processing and dyslexia. She is also very interested in microscopy and would welcome the opportunity to see live demonstrations of imaging techniques. If you are interested in meeting with her, please contact me. Thank you all for your interest and enjoy these last few days of August! Best wishes, Sari Sari S. Hannila, PhD Director of Outreach, Manitoba Neuroscience Network cid:image004.jpg@01D158FE.B69B8D00

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Research Seminar: Dr. Ravi Rungta | Monday Aug. 13 @ 12 Noon
by Kelly Jorundson 01 Aug '18

01 Aug '18

Everyone is invited! The Department of Pharmacology and Therapeutics Seminar Series DATE: Monday, August 13, 2018 TIME: 12:00 pm LOCATION: 071 Apotex Bldg. Ravi Rungta EMBO / Marie Curie Postdoctoral Fellow INSERM U1128 and Université Paris Descartes, Laboratory of Neurophysiology and New Microscopy TOPIC: "Linking synaptic activation to hemodynamic signals for functional imaging " For more information contact: Kelly Jorundson e: kjorund(a)sbrc.ca Kelly Jorundson Administrative Manager, Division of Neurodegenerative Disorders St. Boniface Hospital Research Department of Pharmacology & Therapeutics University of Manitoba Email: kjorund(a)sbrc.ca <mailto:kjorund@sbrc.ca> or kjorundson(a)sbgh.mb.ca <mailto:Kelly.jorundson@umanitoba.ca> Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies.

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2018 Discovery Day in Health Sciences at U of M - CALL FOR PRESENTERS
by Manitoba Neuroscience Network 31 Jul '18

31 Jul '18

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Dr. Phillip Gardiner phillip.gardiner(a)ad.umanitoba.ca The Canadian Medical Hall of Fame Discovery Day in Health Sciences University of Manitoba Friday, November 9, 2018 CALL FOR PRESENTERS PLEASE CIRCULATE AMONGST YOUR COLLEAGUES Hi Dr. Gardiner: We are pleased to once again partner with the Rady Faculty of Health Sciences in offering Manitoba high school students and teachers the opportunity to explore careers in medicine and other sciences. We are looking for dynamic presenters to join us in this exciting outreach initiative to educate, inspire and encourage curious minds. The objective of the day is to get students thinking outside the box and to spark their interest in considering a future career in the health sciences. Our formal letter of invitation with further details is attached, along with the days agenda and editable PDF forms. We would very much welcome the inclusion of the Spinal Cord Research Centre in this years program. We invite all faculty, technicians, clinicians, residents and grad/undergrad students interested in taking part. Your assistance in circulating this invitation amongst your colleagues would be greatly appreciated. SUBMISSION DEADLINE: Wednesday, September 12, 2018 Questions and completed forms can be directed to my attention via email. With thanks for your time and consideration, Janice Janice McNorgan Information Systems and Program Coordinator | Coordonnatrice, Systèmes d'information et Programmes Canadian Medical Hall of Fame | Le Temple de la renommée médicale canadienne 202-267 Dundas Street, London ON N6A 1H2 | office: 519.488.2003 ext. 6111 | fax: 519.488.2999 Honouring Excellence. Preserving History. Connecting Generations. Be inspired. Explore the stories of our Laureates <http://www.cdnmedhall.org/laureates> www.cdnmedhall.org/laureates Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: <mailto:kjorund@sbrc.ca> kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies. ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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Reminder - please note **room change** MNN Lecture - Dr. V. Wee Yong | Fri. Jul 27th
by Manitoba Neuroscience Network 23 Jul '18

23 Jul '18

cid:image001.jpg@01D158FE.B69B8D00 S P E C I A L L E C T U R E Presented by the Manitoba Neuroscience Network, Spinal Cord Research Centre, Regenerative Medicine Program, and Department of Physiology & Pathophysiology D AT E Friday, July 27th, 2018 2 pm L O C AT I O N 071 Apotex Bldg. Bannatyne Campus S P E A K E R DR. V. WEE YONG Professor and Canada Research Chair in Neuroimmunology The Hotchkiss Brain Institute University of Calgary Director, Alberta Multiple Sclerosis Network Past President, International Society of Neuroimmunology T O P I C Modulating microglia and macrophage activity to improve neurological outcomes Biosketch: Dr. V. Wee Yong is a Professor at the University of Calgary, Canada, and the Canada Research Chair in Neuroimmunology. He co-leads the Multiple Sclerosis (MS) NeuroTeam of the Hotchkiss Brain Institute at the University of Calgary, and he directs the provincial Alberta MS Network. Dr. Yongs research interests lie in the area of neuroimmunology, neuroprotection and CNS regeneration, and his projects are guided by MS and brain tumors. Dr. Yong has published 290 peer-reviewed manuscripts and his research has been translated into Phase III clinical trials in MS and spinal cord injury. His work has been cited over 18,800 times by other authors (web of science; h-index of 76). Dr. Yong is a past chair of the Medical Advisory Committee of the MS Society of Canada; this and other volunteer activities resulted in him receiving the Queens Golden Jubilee Year Medallion. Dr. Yong is on the editorial board of 7 international journals; he is the Honorary Editor-in-Chief of the journal Neuroimmunology and Neuroinflammation. He has been the President of the International Society of Neuroimmunology (2014-2016). Dr. Yong is an elected fellow of both the Canadian Academy of Health Sciences and the Royal Society of Canada. He is the 2017 Allyn Taylor International Prize in Medicine winner. Some publications the past 5 years: Lau L, Cua R, Keough MB, Haylock-Jacob S, Yong VW, Pathophysiology of the brain extracellular matrix: A new target for remyelination, Nature Rev Neurosci 14:722-729, 2013 Stephenson E, Nathoo N, Mahjoub Y, Dunn JF, Yong VW, Iron in Multiple Sclerosis: Roles in neurodegeneration and repair, Nature Rev Neurol 10:459-468, 2014 Sarkar S, Doring A, Zemp F, Silva C, Lun X, Wang X, Kelly J, Hader W, Hamilton M, Mercier P, Dunn JF, Kinniburgh D, van Rooijen N, Robbins S, Forsyth P, Cairncross G, Weiss S, Yong VW, Therapeutic activation of macrophages/microglia to suppress brain tumor-initiating cells, Nature Neurosci 17:46-55, 2014 Keough MB, Rogers JA, Zhang P, Jensen SK, Robertson E, Chen T, Lau LW, Rawji KS, Plemel JR, Koch M, Ling CC, Yong VW, An inhibitor of chondroitin sulfate proteoglycan synthesis promotes CNS remyelination, Nature Communications 7:11312, 1-12, 2016 Clemente-Casares X, Blanco J, Ambalavalan P, Singha S, Yamanouchi J, Fandos C, Tsai S, Wang J, Agrawal S, Keough M, Yong VW, James E, Moore A, Yang Y, Stratmann T, Serra P, Santamaria P, Expanding antigen-specific regulatory networks to treat autoimmunity, Nature b530:434-440, 2016 Mishra MK, Yong VW, Myeloid cells: targets of medications in multiple sclerosis, Nature Rev Neurol 12:539-551, 2016 Metz LM, Li DKB, Traboulsee AL, Duquette P, Eliasziw M, Cerchiaro G, Greenfield J, Riddehough A, Yeung M, Kremenchutzky M, Vorobeychik G, Freedman MS, Bhan V, Blevins G, Marriott JJ, Grand'Maison F, Lee L, Thibault M, Hill MD, Yong VW for the Minocycline in MS Study Team, Trial of minocycline in clinically isolated syndrome of multiple sclerosis, New Engl J Med 376:2122-2133, 2017 Plemel JR, Liu WQ, Yong VW, Remyelination therapies: a new direction and challenge in multiple sclerosis, Nature Rev Drug Discovery 16:617-634, 2017 Faissner S, Mishra M, Wang J, Fan Y, Silva C, Rauw G, Metz L, Koch M, Yong VW, Systematic screening of generic drugs for progressive multiple sclerosis: Clomipramine as a promising therapeutic, Nature Communications 8:1990, 2017 Stephenson E, Mishra M, Moussienko D, Yong VW, Chondroitin sulfate proteoglycans as novel drivers of leukocyte infiltration in multiple sclerosis, Brain 141:1094-1110, 2018 Sarkar S, Yang R, Rawji K, Poon C, Mirzaei R, Zemp FJ, Bose P, Kelly J, Dunn JF, Yong VW, Control of brain tumor growth by reactivating monocytes and macrophages with niacin, resubmission invited by Science Translational Med For more information on this lecture, please contact Soheila Karimi Tel: 204.272.3109 Email: Soheila.karimi(a)umanitoba.ca Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: <mailto:kjorund@sbrc.ca> kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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Nick Shepel Travel Award Winner (2018)
by Kelly Jorundson 18 Jul '18

18 Jul '18

We are pleased to announce that Crystal Acosta (Supervisor: Hope Anderson) has been awarded this years' St. Boniface Hospital Foundation - Nick Shepel Travel Award (a value of up to $750 CAD). This award will help to cover the travel costs associated with Crystal's attendance at the national Society for Neuroscience Meeting to present a research poster. Congrats Crystal! The Nick Shepel fund was established by the Division of Neurodegenerative Disorders, St. Boniface Hospital Research Centre, to honor Nick Shepel who was an outstanding researcher, friend and leader. Nick was a true inspiration to his laboratory partners and brought fire, humor, and a desire to always excel. His insistence to always try better has had a permanent effect on his lab mates and peers. Nick led by example and taught that detailed preparation and execution of experiments ensured reliable results. The purpose of this fund shall be to recognize a young investigator (specifically in the neuroscience area) by providing an annual award(s) to support travel costs associated with the applicant's attendance at an upcoming national/international conference where the applicant is presenting a poster or oral presentation. /sent on behalf of Paul Fernyhough Kelly Jorundson Administrative Manager, Division of Neurodegenerative Disorders St. Boniface Hospital Research Department of Pharmacology & Therapeutics University of Manitoba Email: kjorund(a)sbrc.ca <mailto:kjorund@sbrc.ca> or kjorundson(a)sbgh.mb.ca <mailto:Kelly.jorundson@umanitoba.ca> Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies.

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MNN Lecture - Dr. V. Wee Yong | Fri. Jul 27th ***2 pm***
by Manitoba Neuroscience Network 16 Jul '18

16 Jul '18

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Dr. Soheila Karimi S P E C I A L L E C T U R E Presented by the Manitoba Neuroscience Network, Spinal Cord Research Centre, Regenerative Medicine Program, and Department of Physiology & Pathophysiology D AT E Friday, July 27th, 2018 2 pm L O C AT I O N Room 431 - Department of Physiology and Pathophysiology Basic Medical Sciences Bldg. Bannatyne Campus S P E A K E R DR. V. WEE YONG Professor and Canada Research Chair in Neuroimmunology The Hotchkiss Brain Institute University of Calgary Director, Alberta Multiple Sclerosis Network Past President, International Society of Neuroimmunology T O P I C Modulating microglia and macrophage activity to improve neurological outcomes Biosketch: Dr. V. Wee Yong is a Professor at the University of Calgary, Canada, and the Canada Research Chair in Neuroimmunology. He co-leads the Multiple Sclerosis (MS) NeuroTeam of the Hotchkiss Brain Institute at the University of Calgary, and he directs the provincial Alberta MS Network. Dr. Yong’s research interests lie in the area of neuroimmunology, neuroprotection and CNS regeneration, and his projects are guided by MS and brain tumors. Dr. Yong has published 290 peer-reviewed manuscripts and his research has been translated into Phase III clinical trials in MS and spinal cord injury. His work has been cited over 18,800 times by other authors (web of science; h-index of 76). Dr. Yong is a past chair of the Medical Advisory Committee of the MS Society of Canada; this and other volunteer activities resulted in him receiving the Queen’s Golden Jubilee Year Medallion. Dr. Yong is on the editorial board of 7 international journals; he is the Honorary Editor-in-Chief of the journal Neuroimmunology and Neuroinflammation. He has been the President of the International Society of Neuroimmunology (2014-2016). Dr. Yong is an elected fellow of both the Canadian Academy of Health Sciences and the Royal Society of Canada. He is the 2017 Allyn Taylor International Prize in Medicine winner. Some publications the past 5 years: Lau L, Cua R, Keough MB, Haylock-Jacob S, Yong VW, Pathophysiology of the brain extracellular matrix: A new target for remyelination, Nature Rev Neurosci 14:722-729, 2013 Stephenson E, Nathoo N, Mahjoub Y, Dunn JF, Yong VW, Iron in Multiple Sclerosis: Roles in neurodegeneration and repair, Nature Rev Neurol 10:459-468, 2014 Sarkar S, Doring A, Zemp F, Silva C, Lun X, Wang X, Kelly J, Hader W, Hamilton M, Mercier P, Dunn JF, Kinniburgh D, van Rooijen N, Robbins S, Forsyth P, Cairncross G, Weiss S, Yong VW, Therapeutic activation of macrophages/microglia to suppress brain tumor-initiating cells, Nature Neurosci 17:46-55, 2014 Keough MB, Rogers JA, Zhang P, Jensen SK, Robertson E, Chen T, Lau LW, Rawji KS, Plemel JR, Koch M, Ling CC, Yong VW, An inhibitor of chondroitin sulfate proteoglycan synthesis promotes CNS remyelination, Nature Communications 7:11312, 1-12, 2016 Clemente-Casares X, Blanco J, Ambalavalan P, Singha S, Yamanouchi J, Fandos C, Tsai S, Wang J, Agrawal S, Keough M, Yong VW, James E, Moore A, Yang Y, Stratmann T, Serra P, Santamaria P, Expanding antigen-specific regulatory networks to treat autoimmunity, Nature b530:434-440, 2016 Mishra MK, Yong VW, Myeloid cells: targets of medications in multiple sclerosis, Nature Rev Neurol 12:539-551, 2016 Metz LM, Li DKB, Traboulsee AL, Duquette P, Eliasziw M, Cerchiaro G, Greenfield J, Riddehough A, Yeung M, Kremenchutzky M, Vorobeychik G, Freedman MS, Bhan V, Blevins G, Marriott JJ, Grand'Maison F, Lee L, Thibault M, Hill MD, Yong VW for the Minocycline in MS Study Team, Trial of minocycline in clinically isolated syndrome of multiple sclerosis, New Engl J Med 376:2122-2133, 2017 Plemel JR, Liu WQ, Yong VW, Remyelination therapies: a new direction and challenge in multiple sclerosis, Nature Rev Drug Discovery 16:617-634, 2017 Faissner S, Mishra M, Wang J, Fan Y, Silva C, Rauw G, Metz L, Koch M, Yong VW, Systematic screening of generic drugs for progressive multiple sclerosis: Clomipramine as a promising therapeutic, Nature Communications 8:1990, 2017 Stephenson E, Mishra M, Moussienko D, Yong VW, Chondroitin sulfate proteoglycans as novel drivers of leukocyte infiltration in multiple sclerosis, Brain 141:1094-1110, 2018 Sarkar S, Yang R, Rawji K, Poon C, Mirzaei R, Zemp FJ, Bose P, Kelly J, Dunn JF, Yong VW, Control of brain tumor growth by reactivating monocytes and macrophages with niacin, resubmission invited by Science Translational Med For more information on this lecture, please contact Soheila Karimi Tel: 204.272.3109 Email: Soheila.karimi(a)umanitoba.ca Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: <mailto:kjorund@sbrc.ca> kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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Special Visiting Speaker -- Thursday July 5, 2pm
by Manitoba Neuroscience Network 04 Jul '18

04 Jul '18

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Eftekhar Eftekharpour Everyone is invited! REGENERATIVE MEDICINE PROGRAM VISITING SPEAKER DR. YUEQIN ZHOU Cedars-Sinai Medical Centre Neurodegenerative Disease Program Los Angeles "Restoring Mitofusin balance in the nervous system prevents axonal degeneration in a CMT2A mouse model" Thursday July 5th 2:00 P.M Room 626 BMSB

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Announcement of NEW Neuroscience-related IMED Graduate course offerings.
by Kelly Jorundson 28 Jun '18

28 Jun '18

/sent on behalf of Brent Fedirchuk Brent.Fedirchuk(a)umanitoba.ca Subject: Announcement of NEW Neuroscience-related IMED Graduate course offerings. I would like to distribute the notice attached as widely as possible to the local Neuroscience academic community (including students). It is announcement of a new suite of 4 Neuroscience graduate courses that are each 1.5 credit hours. These courses will be offered successively during the 2018 Fall and 2019 Winter academic terms and will replace the IMED7101 and IMED7102 courses (3 credit hours) that have previously been offered. June 2018 Notice of NEW Neuroscience Graduate Course Offerings (please post) Fall Term 2018: IMED7112 - Fundamental Cellular Neurobiology (Sept - Oct) IMED7114 - Fundamental Neural Development and Plasticity (Oct - Dec) Winter Term 2019: IMED7116 - Fundamental Systems Neuroscience (Jan - Feb) IMED7118 - Fundamental Neurobiology of Disease (Mar - Apr) * These 4 new 1.5 credit hour graduate courses will replace: IMED7101 Fundamentals of Neuroscience I (3 credit hours) and, IMED7102 Fundamentals of Neuroscience II (3 credit hours) * None of these courses is a prerequisite to the others, so you may choose to take some, or all of them. * These interdisciplinary courses will held at the Rady Faculty of Health Sciences, Bannatyne Campus Tuesdays & Thursdays 3:00 - 4:30 p.m. Dept. Physiology & Pathophysiology Conference Room, 431 BMSB, (4th Floor, Basic Medical Sciences Building) Rady Faculty of Health Sciences Campus Registration is open to all graduate students enrolled in any Faculty/College/Department interested in Neuroscience from the Fort Garry or Bannatyne Campuses, and the St. Boniface Research Centre. For more information contact: Dr. Brent Fedirchuk brent.fedirchuk(a)umanitoba.ca 204 789-3762 Dr. Tabrez Siddiqui (IMED7112) Tabrez.Siddiqui(a)umanitoba.ca 204 318-2564 Dr. Hassan Marzban (IMED7114) Hassan.Marzban(a)umanitoba.ca 204 789-3467 Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca <mailto:kjorund@sbrc.ca> Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies. ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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Research Presentation - June 28th!
by Kae Normandeau 26 Jun '18

26 Jun '18

Research Presentation Date: June 28 Time: 11:30-12:30pm Location: R230, Med Rehab Building (771 McDermot Avenue) Click here for map<http://umanitoba.ca/about/map/bannatyne/> Scott Yuzwa, PhD. Post-doctoral fellow in the labs of Drs. Freda Miller and David Kaplan at the Hospital for Sick Children Candidate for UMFA position in the Department of Pathology Topic: "Unraveling cellular communication and cell type diversity in the developing brain" Kae Normandeau Administrative Manager Neuroscience Research Program SR440 KIAM Building P: 204-318-2569 E: kae.normandeau(a)umanitoba.ca<mailto:kae.normandeau@umanitoba.ca>

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