- Neuro-All - University of Manitoba Mailing Lists

Sept 24 -St Boniface Hosp. Res Cohen auditorium - Chief Science Officer from the Alz Soc will speak at St Boniface
by membership＠manitobaneuroscience.ca 09 Sep '19

09 Sep '19

/sent on behalf of Benedict C. Albensi, PhD, BCMAS, CRQM Manitoba Dementia Research Chair Everyone is invited! Spotlight on Dementia Research: Whats Happening Now and its Impact on the Future <https://alzheimer.mb.ca/wp-content/uploads/2019/07/Spotlight-on-Research-Se pt-24-2019.pdf> Click here to view the poster. Keynote Speaker Dr. Saskia Sivananthan Chief Research & KTE Officer, Alzheimer Society of Canada Tuesday, September 24, 2019 7 8:30 pm Samuel N. Cohen Auditorium St. Boniface Hospital Research 351 Tache Avenue, Winnipeg, MB Around the world, researchers are taking significant strides to look for ways to prevent dementia, to improve the quality of life of those impacted and to ultimately find a cure. Come to hear Dr. Sivananthan, a neuroscientist, global policy leader and Chief Science Officer at the Alzheimer Society of Canada talk about the latest research, new findings and what it means for the future of dementia. Chair: Dr. Benedict C. Albensi, Manitoba Dementia Research Chair; Everett Endowment Fund Chair, St. Boniface Hospital Research Centre Limited seating! Three easy ways to register! 1. Email alzmb(a)alzheimer.mb.ca <mailto:alzmb@alzheimer.mb.ca> 2. Call 204-943-6622 or 1-800-378-6699 3. <https://secure2.convio.net/alzmb/site/Ecommerce;jsessionid=00000000.app216a ?store_id=1741&NONCE_TOKEN=02328DC99D5C253737865993A9786753> Click here to register online today! Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA Email: kjorund(a)sbrc.ca <mailto:kjorund@sbrc.ca> Tel: 204.235.3939 Fax: 204.237.4092 . ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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2019/20 MNN Seminar Series
by networking＠manitobaneuroscience.ca 27 Aug '19

27 Aug '19

Dear colleagues, Hope you have had a good summer. I am reaching out to you to identify speakers for our 2019/2020 MNN seminar series. Please let me know at the earliest possible your top 3 dates suitable for a talk. The current slots open are on the following dates @ 9AM. September 27th October 25th February 28th March 27th April 24th May 29th Thank you, Tabrez Tabrez.siddiqui(a)umanitoba.ca <mailto:Tabrez.siddiqui@umanitoba.ca> /sent on behalf of Tabrez Siddiqui Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA Email: kjorund(a)sbrc.ca <mailto:kjorund@sbrc.ca> Tel: 204.235.3939 Fax: 204.237.4092 . ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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Outreach opportunity - Sport Manitoba Peak Performance Seminars
by outreach＠manitobaneuroscience.ca 19 Jul '19

19 Jul '19

cid:image001.jpg@01D158FE.B69B8D00 Dear colleagues, The MNN has received an invitation from Sport Manitoba to participate in their Peak Performance seminar series. They are looking for a speaker to present on the topic of sleep and athletic performance, and this could extend into areas such as attention, cognition, and circadian rhythms. Details are provided below and as you can see, an honorarium is also provided. If you are interested, please contact me and I will pass your information on to Sport Manitoba. Best wishes, Sari Sari S. Hannila, PhD Director of Outreach, Manitoba Neuroscience Network Associate Professor, Department of Human Anatomy and Cell Science University of Manitoba cid:image004.jpg@01D158FE.B69B8D00 From: Neal Prokop [mailto:Neal.Prokop@sportmanitoba.ca] Sent: Monday, July 15, 2019 11:55 AM To: outreach(a)manitobaneuroscience.ca Cc: Jeff Wood Subject: MNN Community Outreach, Sport Manitoba Peak Performance Seminars Hi Dr. Sari, Sport Manitoba Performance delivers a series of Peak Performance Seminars (P-Series) that take place monthly from October to March. The talks are targeted to high performance amateur athletes, coaches and/or parents to help with development and preparing athletes for competition. We're very interested in incorporating the topic of 'sleep' as one of our topics this year. Is there anyone within the MNN network that would be interested in speaking on the importance of sleep for athletes, sleep strategies for a good night sleep, sleep cycles, naps or other related topics. When researching speakers, we came across Dr. Marcus Ng, but there may be another speaker within the network that could be good fit. All presentations take place at Sport Manitoba's Conference Room (capacity 80), located at 145 Pacific Avenue, Winnipeg Manitoba. The series is also broadcasted via webstream so that athletes in rural regions of the province are able to obtain the information presented. The talks are 45-50-minutes including a 5-10 minute period for questions. All presenters are compensated $200 for their time and efforts! Look forward to hearing your response! Have a great day! Neal Prokop MSc CSCS PES | Sport Performance Specialist Sport Manitoba P: 204.925.5698 | neal.prokop(a)sportmanitoba.ca

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F new IMED neuroscience course
by Kelly Jorundson 10 Jul '19

10 Jul '19

Sent on Behalf of Drs. Soheila Karimi and Eftekhar Eftekharpour Dept. Physiology and Pathophysiology, Regenerative Medicine Program We are pleased to offer a new interdisciplinary medicine course titled: Neural Stem Cells: Biology and Regenerative Medicine Applications. This course (IMED7104) will discuss the current concepts in neural stem cells from basic neurobiology (development, fate specification and maintenance) to their potential clinical applications in treating a broad range of neurological disorders through activation of endogenous cell population, cellular reprograming, cell transplantation as well as gene and drug delivery. Neural stem cells play critical roles in the developing and adult nervous system and the course is developed to build the necessary knowledge for graduate students and residents within all disciplines in neurosciences. Course schedule: March 11-April 22, 2020 (1.5 credit hour). Please see the attached flyer and syllabus for more information. Please direct your questions to Soheila Karimi (Soheila.Karimi(a)umanitoba.ca) Please follow us on Twitter @KarimiLab Lab Site: http://home.cc.umanitoba.ca/~karimis/ Soheila Karimi, PhD Associate Professor of Physiology and Pathophysiology Principal Investigator, Neural Regeneration and Stem Cell Program Senior Scientist, Regenerative Medicine Program Principal Investigator, Spinal Cord Research Center Rady Faculty of Health Sciences Max Rady College of Medicine University of Manitoba Address: 745 Bannatyne Avenue, 629 BMSB Winnipeg, MB R3E 0J9 Canada Phone: (204) 272-3109

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Announcing MNN's new art-science collaboration!
by Sari Hannila 03 Jul '19

03 Jul '19

[cid:image001.jpg@01D158FE.B69B8D00] [cid:image005.jpg@01D52048.82783DB0] Hello everyone, Following the success of Neurocraft, many of you have asked if there would be more opportunities to connect with local artists, and today I am pleased to announce the launch of Dura Mater: Reflections on Neurofeminism, our new collaboration with Mentoring Artists for Women's Art (MAWA). MAWA was founded in 1983 and provides mentoring, networking, and professional development opportunities for women artists in Manitoba. Their members include such distinguished artists as Ione Thorkelsson, Diana Thorneycroft, and Shawna Dempsey. You can find out more about them at www.mawa.ca<http://www.mawa.ca> Are you interested in participating? Here are a few key points to consider. * This collaboration is open to all MNN faculty members. Depending on the response, students and postdocs may be considered as well. * There are six spots available. * The artists will submit their applications by September 18th and pairings will be finalized in the fall. Participating scientists will have the opportunity to view the artists' applications and identify potential partners. * The program will run from January-December, 2020. An exhibition of the finished pieces will be held at the Buhler Gallery at St. Boniface Hospital in March, 2020. * MAWA has a very strong educational mandate, and so, this program will be far more structured than Neurocraft. Participants will be required to meet with their partners for a minimum of two hours per month, and there will also be six group meetings that will be held every two months at MAWA's offices. These meetings are mandatory and will involve group discussions, lectures, and opportunities to share the work that has been produced. * Participating in this collaboration will therefore involve a 36 hour time commitment (minimum) over the course of the year and it will also require flexibility in your schedule to accommodate the individual and group meetings. * Is this only open to women? Certainly not! The program is open to all genders. The vast majority of the artists will be women, and they will likely be interested in exploring feminist themes in their work, but participants are free to pursue any avenue of inquiry. Collaborative works are also encouraged. The attached flyer was distributed to MAWA members earlier this month and it provides some additional information about the program. It promises to be a unique and engaging intellectual experience, so I hope you will consider taking part. If you are interested, please send me an email prior to September 18th, and if you have any questions, feel free to send those along as well. As always, thank you for your support of the MNN and our outreach program. Thank you also to everyone who attended the annual meeting, and the organizers, Dom and Renee, who did an outstanding job! Best wishes, Sari Sari S. Hannila, PhD Director of Outreach, Manitoba Neuroscience Network Associate Professor, Department of Human Anatomy and Cell Science University of Manitoba [cid:image005.jpg@01D52048.82783DB0] [cid:image004.jpg@01D158FE.B69B8D00]

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Dr. Ed Boyden here tomorrow!
by Chris Anderson 12 Jun '19

12 Jun '19

[cid:image001.jpg@01D158FE.B69B8D00] Did you know that... The 2019 GAIRDNER SYMPOSIUM is happening tomorrow? Thursday, JUNE 13, 2019 [https://umanitoba.ca/outreach/conferences/research_days/media/CSHRF_2019_Sy…] Speakers include Professor in Neurotechnology, DR. EDWARD BOYDEN [http://umanitoba.ca/outreach/conferences/research_days/media/Ed_Boyden_Phot…] Dr. Ed Boyden Massachusetts Institute of Technology (MIT) "Tools for Analyzing and Controlling Complex Biological Systems" BASIC MEDICAL SCIENCES BUILDING 9:15 AM (Introduced by Dr. Jillian Stobart) OTHER SPEAKERS * Dr. Richard Hynes - Massachusetts Institute of Technology "Extracellular Matrix Vulnerabilities in Cancer" (Introduced by Dr. Ian Dixon) * Dr. Lewis Kay - Hospital for Sick Children & University of Toronto "The Important Role of Dynamics in the Function and Misfunction of Molecular Machines" (Introduced by Dr. Ji Hyun Ko) * Dr. Nada Jabado - McGill University "The Peter Pan Syndrome: Stalled Development in Pediatric Brain Tumors" (Introduced by Dr. Tamra Ogilivie) * Dr. Antoine Hakim - Ottawa Hospital Research Institute "Bringing Science to Society: The Recent Story of Stroke Care in Canada" (Introduced by Dr. Tabrez Siddiqui) STRATION OPENS FOR THE COMPLETE PROGRAM: 2019 Gairdner Symposium Program<http://umanitoba.ca/outreach/conferences/research_days/media/CSHRF_2019_Sym…> INFORMATION ON THE SPEAKERS: 2019 Gairdner Symposium Speakers<http://umanitoba.ca/outreach/conferences/research_days/symposium.html> For more information: sforum(a)umanitoba.ca<mailto:sforum@umanitoba.ca> ****************************************** [cid:image003.jpg@01D159B3.9F0B9710]<https://nam02.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.manito…> [cid:image007.png@01D29326.7E26D480]<https://nam02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.faceb…> [cid:image009.jpg@01D29326.7E26D480] <https://nam02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.insta…> [cid:image010.png@01D29326.7E26D480] <https://nam02.safelinks.protection.outlook.com/?url=https%3A%2F%2Ftwitter.c…>

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REMINDER: Tomorrow MNN Seminar: - Tamra Ogilvie | Friday May 31 @ 9am
by Kelly Jorundson 30 May '19

30 May '19

[cid:image001.jpg@01D158FE.B69B8D00] S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D A T E Friday, May 31, 2019 9:00 AM L O C AT I O N PX236/238 PsycHealth Blding S P E A K E R Tamra Ogilvie, Ph.D.<http://umanitoba.ca/medicine/units/biochem/faculty/t_werbowetski-ogilvie.ht…> Canada Research Chair in Neuro-oncology and Human Stem Cells Associate Professor, Regenerative Medicine Program Biochemistry & Medical Genetics and Physiology & Pathophysiology Max Rady College of Medicine Rady Faculty of Health Sciences University of Manitoba T O P I C Novel gene networks regulating self-renewal and differentiation in medulloblastoma A B S T R AC T OTX2 is a potent oncogenic driver of tumor growth and cell cycle progression in Group 3 medulloblastoma. However, the specific mechanisms by which OTX2 represses neural differentiation in these highly aggressive tumors are not well characterized. We have utilized ChIP-sequencing combined with extensive medulloblastoma patient transcriptome and proteomics data to identify and subsequently validate a novel OTX2 regulatory network that controls Group 3 medulloblastoma cell fate decisions. OTX2 directly restricts the expression of neuronal differentiation genes encoding transcription factors including the novel target genes PAX3 and PAX6. Expression of PAX3 and PAX6 is significantly lower in Group 3 MB patients and is correlated with reduced survival. Similar to OTX2 silencing, PAX3 and PAX6 overexpression inhibit self-renewal and enhance neuronal differentiation in vitro while PAX3, on its own, increases survival in vivo. Finally, we identify mTORC1 and EPHB2 forward signaling as downstream effectors of OTX2-PAX3, thus highlighting axon guidance and protein synthesis pathways as novel therapeutic targets and key players in Group 3 medulloblastoma pathogenesis. O B J E C T I V E S * Understand the genetic, molecular and cellular heterogeneity associated with the pediatric brain tumor medulloblastoma * Understand the multifaceted role of OTX2 in medulloblastoma pathogenesis * Describe the functional outcome of increased PAX gene expression on medulloblastoma tumorigenic properties in vitro and in vivo For more information, contact the MNN office @ 204.235.3939 Tabrez Siddiqui Chair, MNN Seminar Series E: Tabrez.siddiqui(a)umanitoba.ca<mailto:Tabrez.siddiqui@umanitoba.ca> Kelly Jorundson Manitoba Neuroscience Network Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA Email: kjorund(a)sbrc.ca<mailto:kjorund@sbrc.ca> Tel: 204.235.3939 Fax: 204.237.4092 . ****************************************** [cid:image003.jpg@01D159B3.9F0B9710]<http://www.manitobaneuroscience.ca/> [cid:image007.png@01D29326.7E26D480]<https://www.facebook.com/manitobaneuroscience/?fref=ts> [cid:image009.jpg@01D29326.7E26D480] <https://www.instagram.com/manitobaneuroscience/> [cid:image010.png@01D29326.7E26D480] <https://twitter.com/manitobaneuro>

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REMINDER: MNN Seminar: - Tamra Ogilvie | Friday May 31 @ 9am
by Manitoba Neuroscience Network 27 May '19

27 May '19

cid:image001.jpg@01D158FE.B69B8D00 S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D A T E Friday, May 31, 2019 9:00 AM L O C AT I O N PX236/238 PsycHealth Blding S P E A K E R Tamra Ogilvie, Ph.D. <http://umanitoba.ca/medicine/units/biochem/faculty/t_werbowetski-ogilvie.ht ml> Canada Research Chair in Neuro-oncology and Human Stem Cells Associate Professor, Regenerative Medicine Program Biochemistry & Medical Genetics and Physiology & Pathophysiology Max Rady College of Medicine Rady Faculty of Health Sciences University of Manitoba T O P I C Novel gene networks regulating self-renewal and differentiation in medulloblastoma A B S T R AC T OTX2 is a potent oncogenic driver of tumor growth and cell cycle progression in Group 3 medulloblastoma. However, the specific mechanisms by which OTX2 represses neural differentiation in these highly aggressive tumors are not well characterized. We have utilized ChIP-sequencing combined with extensive medulloblastoma patient transcriptome and proteomics data to identify and subsequently validate a novel OTX2 regulatory network that controls Group 3 medulloblastoma cell fate decisions. OTX2 directly restricts the expression of neuronal differentiation genes encoding transcription factors including the novel target genes PAX3 and PAX6. Expression of PAX3 and PAX6 is significantly lower in Group 3 MB patients and is correlated with reduced survival. Similar to OTX2 silencing, PAX3 and PAX6 overexpression inhibit self-renewal and enhance neuronal differentiation in vitro while PAX3, on its own, increases survival in vivo. Finally, we identify mTORC1 and EPHB2 forward signaling as downstream effectors of OTX2-PAX3, thus highlighting axon guidance and protein synthesis pathways as novel therapeutic targets and key players in Group 3 medulloblastoma pathogenesis. O B J E C T I V E S * Understand the genetic, molecular and cellular heterogeneity associated with the pediatric brain tumor medulloblastoma * Understand the multifaceted role of OTX2 in medulloblastoma pathogenesis * Describe the functional outcome of increased PAX gene expression on medulloblastoma tumorigenic properties in vitro and in vivo For more information, contact the MNN office @ 204.235.3939 Tabrez Siddiqui Chair, MNN Seminar Series E: Tabrez.siddiqui(a)umanitoba.ca Kelly Jorundson Manitoba Neuroscience Network Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 . ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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Reminder: Registration deadline - MNN 2019 meeting *TODAY
by Manitoba Neuroscience Network 17 May '19

17 May '19

cid:image001.jpg@01D158FE.B69B8D00 *TODAY IS YOUR LAST DAY TO REGISTER! The MNN is pleased to announce that the 2019 Scientific Meeting will be held JUNE 7. The meeting is co-chaired by Dr. Domenico Di Curzio and Dr. Renée Douville and will be held at the University of Winnipeg. There is an engaging program planned, featuring a visit and talk by Canadian Research Council Chair in Developmental Neurogenetics Dr. Daniel Goldowitz (University of British Columbia) a public lecture by Dr. Janice Robertson (University of Toronto), a leading expert in Amyotrophic Lateral Sclerosis neuropathology and therapeutic development. The scientific event will be capped off with a networking mixer and neuroscience art silent auction at the Winnipeg Art Gallery. Abstracts and registrations are now being accepted. These links and the program can be found at: <https://manitobaneuroscience.ca/annual-meeting/2019mnn/> https://manitobaneuroscience.ca/annual-meeting/2019mnn/ Annual Scientific Meeting | Manitoba Neuroscience Network manitobaneuroscience.ca Highlights Three visiting national speakers Taco bar lunch (Om nom nom!) Poster competition Stellas goodies at coffee breaks SWAG bags and vendor tables WAG Networking mixer after-party Neuroscience art silent auction And more Registration takes 5 minutes or less! NEW this year the student meeting registration rate has been reduced to only $15. Postdocs and community members are $25 and Faculty are $50. Discounted rates apply if attending both scientific session and networking mixer. You may pay by credit card or by University of Manitoba FOP. If you pay by FOP, you will be registered for the meeting immediately, but your payment will be pending. Once the FOP payment is processed, you will receive a receipt and confirmation by email. MNN Scientific Meeting inquiries should be sent to: mnn2019(a)manitobaneuroscience.ca -The MNN Team Kelly Jorundson Manitoba Neuroscience Network Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 . ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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MNN Seminar: - Tamra Ogilvie | Friday May 31 @ 9am
by Manitoba Neuroscience Network 17 May '19

17 May '19

cid:image001.jpg@01D158FE.B69B8D00 S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D A T E Friday, May 31, 2019 9:00 AM L O C AT I O N PX236/238 PsycHealth Blding S P E A K E R Tamra Ogilvie, Ph.D. <http://umanitoba.ca/medicine/units/biochem/faculty/t_werbowetski-ogilvie.ht ml> Canada Research Chair in Neuro-oncology and Human Stem Cells Associate Professor, Regenerative Medicine Program Biochemistry & Medical Genetics and Physiology & Pathophysiology Max Rady College of Medicine Rady Faculty of Health Sciences University of Manitoba T O P I C Novel gene networks regulating self-renewal and differentiation in medulloblastoma A B S T R AC T OTX2 is a potent oncogenic driver of tumor growth and cell cycle progression in Group 3 medulloblastoma. However, the specific mechanisms by which OTX2 represses neural differentiation in these highly aggressive tumors are not well characterized. We have utilized ChIP-sequencing combined with extensive medulloblastoma patient transcriptome and proteomics data to identify and subsequently validate a novel OTX2 regulatory network that controls Group 3 medulloblastoma cell fate decisions. OTX2 directly restricts the expression of neuronal differentiation genes encoding transcription factors including the novel target genes PAX3 and PAX6. Expression of PAX3 and PAX6 is significantly lower in Group 3 MB patients and is correlated with reduced survival. Similar to OTX2 silencing, PAX3 and PAX6 overexpression inhibit self-renewal and enhance neuronal differentiation in vitro while PAX3, on its own, increases survival in vivo. Finally, we identify mTORC1 and EPHB2 forward signaling as downstream effectors of OTX2-PAX3, thus highlighting axon guidance and protein synthesis pathways as novel therapeutic targets and key players in Group 3 medulloblastoma pathogenesis. O B J E C T I V E S * Understand the genetic, molecular and cellular heterogeneity associated with the pediatric brain tumor medulloblastoma * Understand the multifaceted role of OTX2 in medulloblastoma pathogenesis * Describe the functional outcome of increased PAX gene expression on medulloblastoma tumorigenic properties in vitro and in vivo For more information, contact the MNN office @ 204.235.3939 Tabrez Siddiqui Chair, MNN Seminar Series E: Tabrez.siddiqui(a)umanitoba.ca Kelly Jorundson Manitoba Neuroscience Network Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 . ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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