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MNN Meeting REGISTRATION DEADLINE TODAY
by MNN Networking 05 Jun '17

05 Jun '17

One last reminder that the registration deadline for the 2017 MNN Scientific meeting is TODAY, JUNE 5 at the end of the day. There is a tremendous program planned, with world-class keynote speakers, trainee talks, an advocacy session, poster awards, food and more. The meeting in all day June 16 at the Radisson Downtown Winnipeg. To see the program and register, visit: https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/. If you have any questions or difficulties registering or becoming an SFN Winnipeg Chapter 2017 member, please email us at info(a)manitobaneuroscience.ca <mailto:info@manitobaneuroscience.ca> . We hope to see you there! MNN Team ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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MNN Meeting Registration Deadline JUNE 5
by MNN Networking 02 Jun '17

02 Jun '17

This is a reminder that the registration deadline for the MNN Meeting is MONDAY JUNE 5 at the end of the day. Please visit https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/ to register if you intend to go to the meeting, which will be held on June 16 at the Radisson Winnipeg Hotel. If you want to receive a 50% rate discount and receive other membership benefits, please consider becoming a member of the SFN Winnipeg Chapter before registering for the meeting. You can do that here: https://manitobaneuroscience.ca/sfn-chapter-membership/become-a-sfn-chapter- member/. If you are a Lab Head (PI) and you want an all-inclusive lab membership for $120, select "Regular" membership and choose the "All-inclusive" drop-down option. All of your lab members will be able to create their own membership accounts free of additional charges using that option. Meeting registration rates cover costs of facilities, food and visiting speakers, and are as follows: SFN CHAPTER MEMBERS NON-MEMBERS Academic faculty; medical and industry professionals $90 $180 Postdocs, residents, technicians, research associates, emeritus faculty $70 $140 Students (graduate and undergraduate) $50 $100 Thank you and we look forward to an excellent meeting. MNN Team ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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MNN abstract deadline TODAY
by Chris Anderson 29 May '17

29 May '17

Apologies if you have receive this before but some HSC subscribers are not receiving MNN emails consistently. We will fix this shortly and stop sending duplicates. One final reminder that the abstract deadline for the 2017 MNN Scientific Meeting is TODAY, May 29 @ 5:00 pm. Please view meeting information, register and submit abstracts at: https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/. Also a reminder that if you intend to register as a member of the Society for Neuroscience Winnipeg Chapter, you will need to become a 2017 member and create a membership account. If you have been a member in past years, you still must create a membership account for the 2017 membership year. You can do this and then register for the MNN meeting from your account at: https://manitobaneuroscience.ca/sfn-chapter-membership/become-a-sfn-chapter…. Chris Anderson MNN President Tabrez Siddiqui Chair, 2017 MNN Meeting

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MNN Abstract deadline TODAY @ 5 pm
by MNN Networking 29 May '17

29 May '17

One final reminder that the abstract deadline for the 2017 MNN Scientific Meeting is TODAY, May 29 @ 5:00 pm. Please view meeting information, register and submit abstracts at: https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/. Also a reminder that if you intend to register as a member of the Society for Neuroscience Winnipeg Chapter, you will need to become a 2017 member and create a membership account. If you have been a member in past years, you still must create a membership account for the 2017 membership year. You can do this and then register for the MNN meeting from your account at: https://manitobaneuroscience.ca/sfn-chapter-membership/become-a-sfn-chapter- member/. Thank you! MNN Team ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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Reminder - Tomorrow MNN Seminar: Dr. Mojgan Rastagar - Fri May 26th 9am
by Kelly Jorundson 25 May '17

25 May '17

S E M I N A R & V I S I T I N G S P E A K E R S E R I E S DATE: Friday, May 26th, 2017 TIME: 9:00 a.m. LOCATION: PX236/238 PsychHealth Building ***SPEAKER*** MOJGAN RASTEGAR, PH.D Associate Professor - Department of Biochemistry & Medical Genetics, Regenerative Medicine Program, University of Manitoba TOPIC: The bidirectional role of MeCP2 in the brain; a multi layer epigenetic deregulation in MeCP2-associated brain disorders ABSTRACT: Epigenetic mechanisms control gene expression and brain development without any direct change in the corresponding DNA sequences. Recent discoveries have highlighted the importance of epigenetic mechanisms in brain development, neuroscience, and mental health. MeCP2 is an important epigenetic factor in the brain with a bidirectional functional role that is controlled at multiple levels. While, MeCP2 loss-of-function mutations lead to Rett Syndrome (RTT), its gain-of-function genetic mutations cause MECP2 Duplication Syndrome (MDS) through gene duplication or triplication in the patients. RTT and MDS disorders have overlapping symptoms, and the patients show similar and severe neurological phenotypes that include mental disability, seizers, anxiety, and autism. It is well established that impaired protein translation is a characteristic of human RTT neurons. However, the underlying molecular mechanism of this phenotype is not fully understood. To study the underlying pathobiology of RTT and MDS, my lab investigates the bidirectional role of individual MeCP2 isoforms in controlling fundamental molecular pathways that regulate protein translation. We use a combination of primary neural stem cells, RTT and MDS mouse models, and post-mortem human RTT brain tissues to investigate how molecular deficiencies at the cellular levels lead to compromised brain function in RTT, MDS, and other MeCP2-associated brain disorders including autism. For more information contact: Eftekhar Eftekharpour Coordinator - MNN Seminar & Visiting Speaker Series 789-3214 eftekhar.eftekharpour(a)umanitoba.ca Sponsored by: Manitoba Neuroscience Network | Health Sciences Centre | University of Manitoba | St. Boniface Research Centre Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA

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MNN Scientific Meeting - Please submit ABSTRACTS and REGISTER
by Chris Anderson 25 May '17

25 May '17

Dear All, This is a reminder that the Manitoba Neuroscience Network (MNN) is holding its 7th Scientific Meeting June 16 at the Radisson Winnipeg. The 2017 meeting is chaired by Dr. Tabrez Siddiqui and he has assembled a stellar program that includes a featured lecture by one of leaders of the field of neural connectomics, Dr. Jeff Lichtman from Harvard University. Abstract submission and registration have been open for a couple of weeks. This year there have been several events that may interfere with timely abstract submission and we are seeing numbers that are lower than normal for this stage of the process. We are therefore EXTENDING the abstract deadline once more to MONDAY MAY 29 @ 5 pm. No further extensions will be possible after that because we will need to prepare the programs. As an extra incentive to submit, all trainee posters will be judged and there are several cash poster awards available. All MNN meeting attendees, including poster presenters, will need to register. The registration deadline is JUNE 5 @ 5 pm. Rates include coffee/snacks, full lunch and an afternoon reception with food. SFN Winnpeg Chapter members pay rates that are discounted by 50% so please become a member for 2017 before you register. PI's, you can purchase a membership for all of your lab members for one price, allowing each person to register for the MNN meeting as an SFN Chapter member. To LEARN ABOUT THE SFN WINNIPEG CHAPTER AND BECOME A MEMBER: click https://manitobaneuroscience.ca/sfn-chapter-membership/sfn-chapter-membersh… To VIEW MNN MEETING INFORMATION, SUBMIT YOUR ABSTRACT AND REGISTER: click https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/ Thank you for continuing to make the Manitoba Neuroscience Network a valuable and now award-winning networking and outreach hub! If you have any questions about using the new website for the MNN meeting of SFN Chapter membership, please let us know and we will find the answers. Sincerely, Chris Anderson, PhD MNN President chris.anderson(a)umanitoba.ca Tabrez J. Siddiqui, PhD Chair, 2017 MNN Scientific Meeting tabrez.siddiqui(a)umanitoba.ca

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Abstract deadline EXTENDED until Friday May 26 @ 5:00
by MNN Networking 23 May '17

23 May '17

We are pleased to announce that the abstract deadline for the 2017 MNN Scientific Meeting will be extended until FRIDAY MAY 26 at 5:00 pm. The original deadline (today) fell immediately after the May long weekend. We hope meeting delegates will find this extension to be useful. Please note that we will not be able to extend the deadline beyond Friday because a significant amount of time is required for processing and assembling the meeting program. Please submit your abstracts and register for the meeting at https://manitobaneuroscience.ca/events-and-news/annual-scientific-meeting/ Thank you, The MNN Team ****************************************** <http://www.manitobaneuroscience.ca/> <https://www.facebook.com/manitobaneuroscience/?fref=ts> <https://www.instagram.com/manitobaneuroscience/> <https://twitter.com/manitobaneuro>

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MNN Seminar: Dr. Mojgan Rastagar - Fri May 26th 9am
by Manitoba Neuroscience Network 19 May '17

19 May '17

cid:image001.jpg@01D158FE.B69B8D00 S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D AT E Friday, May 26th, 2017 9:00 a.m. LO C AT I O N PX236/238 PsychHealth Building Mojgan Rastegar, Ph.D. <http://rastegar.biochem.umanitoba.ca/> Associate Professor - Department of Biochemistry & Medical Genetics, Regenerative Medicine Program, University of Manitoba Topic: The bidirectional role of MeCP2 in the brain; a multi layer epigenetic deregulation in MeCP2-associated brain disorders ABSTRACT: Epigenetic mechanisms control gene expression and brain development without any direct change in the corresponding DNA sequences. Recent discoveries have highlighted the importance of epigenetic mechanisms in brain development, neuroscience, and mental health. MeCP2 is an important epigenetic factor in the brain with a bidirectional functional role that is controlled at multiple levels. While, MeCP2 loss-of-function mutations lead to Rett Syndrome (RTT), its gain-of-function genetic mutations cause MECP2 Duplication Syndrome (MDS) through gene duplication or triplication in the patients. RTT and MDS disorders have overlapping symptoms, and the patients show similar and severe neurological phenotypes that include mental disability, seizers, anxiety, and autism. It is well established that impaired protein translation is a characteristic of human RTT neurons. However, the underlying molecular mechanism of this phenotype is not fully understood. To study the underlying pathobiology of RTT and MDS, my lab investigates the bidirectional role of individual MeCP2 isoforms in controlling fundamental molecular pathways that regulate protein translation. We use a combination of primary neural stem cells, RTT and MDS mouse models, and post-mortem human RTT brain tissues to investigate how molecular deficiencies at the cellular levels lead to compromised brain function in RTT, MDS, and other MeCP2-associated brain disorders including autism. For more information contact: Eftekhar Eftekharpour Coordinator MNN Seminar & Visiting Speaker Series 789-3214 eftekhar.eftekharpour(a)umanitoba.ca Sponsored by: Manitoba Neuroscience Network | Health Sciences Centre | University of Manitoba | St. Boniface Research Centre Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies. ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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FW: MS Connect 2017 Research Event in Winnipeg
by Manitoba Neuroscience Network 19 May '17

19 May '17

cid:image001.jpg@01D158FE.B69B8D00 /sent on behalf of Dr. Soheila Karimi Subject: MS Connect 2017 Research Event in Winnipeg Hello I appreciate if you distribute the attached flyer and the note below on my behalf to MNN and Physiology. On May 23, 2017, the Multiple Sclerosis Society of Canada has organized an MS Connect 2017 Research Event in Winnipeg. This public event provides awareness on recent advances in MS Research. Dr. Wee Yong, a distinguished researcher in MS and Dr. Arsalan Alizadeh, a PhD candidate in Dr. Soheila Karimis laboratory, will present their research findings in this event. Please join them to learn more about MS research. This is the link to the event: https://mssociety.ca/library/image/oFBGA1HiC2rkphU3ELtwSPnz4gQXfTdD/large.jp g Thank you Soheila -- Soheila Karimi, PhD Associate Professor of Physiology and Pathophysiology Principal Investigator, Spinal Cord Injury and Stem Cell Program Senior Scientist, Regenerative Medicine Program Principal Investigator, Spinal Cord Research Center Rady Faculty of Health Sciences Max Rady College of Medicine University of Manitoba Lab Site: http://home.cc.umanitoba.ca/~karimis/ 745 Bannatyne Avenue, 629 BMSB Winnipeg, MB R3E 0J9 Canada Phone: (204) 272-3109 Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies. ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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****C A N C E L L E D **** TODAY MNN Visiting Speaker Dr. Long-Jun Wu - Fri. May 19
by Manitoba Neuroscience Network 19 May '17

19 May '17

*****C A N C E L L E D ***** Dr. Long-Jun Wu is not able to come to Winnipeg and therefore we have cancelled his research talk scheduled for today at 12noon. We are hopeful that Dr. Wu can reschedule his talk for later in the year. Apologies for any inconvenience. Kelly cid:image001.jpg@01D158FE.B69B8D00 S E M I N A R & V I S I T I N G S P E A K E R S E R I E S D AT E Friday, May 19th, 2017 12:00 Noon LO C AT I O N Theatre C image008Long-Jun Wu, Ph.D. <http://www.mayo.edu/research/faculty/wu-longjun-long-jun-ph-d/bio-20305064> Associate Professor Department of Neurology, Mayo Medical School, Mayo Clinic Topic: Microglia-neuron communication in diseased brain (to be followed by a TRAINEE LUNCH in room SR415 **Please encourage all your neuroscience trainees to attend!) Microglia are the principal immune response cells in the central nervous system. Resting microglia constantly survey the microenvironment in the normal brain. Upon brain dysfunction, microglia are activated and exert detrimental or beneficial effects on the surrounding neurons. However, the molecular mechanisms for microglial activation and function in brain diseases are still controversial. The long-term goal of my lab is to understand microglia-neuron communication in the brain. We are interested in fundamental questions on: (1) How microglia sense neuronal activities? (2) How microglia regulate neuronal and synaptic function? (3) What are the molecular mechanisms and functional consequences of microglia activation in brain diseases? To address these questions, we use the combination of two photon deep-brain imaging, electrophysiology, mouse genetics to dissect the role of microglia in neuronal circuits and in brain disorders. These results provide a novel insight on microglial function in brain emostasis and suggest microglia as a potential therapeutic target for the treatment of brain diseases such as epilepsy, pain and stroke. For more information contact: Eftekhar Eftekharpour Coordinator MNN Seminar & Visiting Speaker Series 789-3214 eftekhar.eftekharpour(a)umanitoba.ca Sponsored by: Manitoba Neuroscience Network | Health Sciences Centre | University of Manitoba | St. Boniface Research Centre Kelly Jorundson Coordinator, Membership & Operations Manitoba Neuroscience Network Email: kjorund(a)sbrc.ca Tel: 204.235.3939 Fax: 204.237.4092 St. Boniface Hospital Albrechtsen Research Centre Room R4046 - 351 Taché Avenue, Winnipeg, MB R2H 2A6 CANADA This email and any attachments may contain confidential, personal and/or privileged information intended for a specific individual and purpose. If you are not the intended recipient, you are hereby notified that any disclosure, copying, retaining, distribution, access, use or modification of the contents of this e-mailed information is strictly prohibited. If you receive this communication in error, please notify the sender immediately and delete or destroy the email message and any attachments or copies. ****************************************** <http://www.manitobaneuroscience.ca/> cid:image003.jpg@01D159B3.9F0B9710 <https://www.facebook.com/manitobaneuroscience/?fref=ts> cid:image007.png@01D29326.7E26D480 <https://www.instagram.com/manitobaneuroscience/> cid:image009.jpg@01D29326.7E26D480 <https://twitter.com/manitobaneuro> cid:image010.png@01D29326.7E26D480

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