Everyone is invited!

MANITOBA NEUROSCIENCE NETWORK 2015/2016 Seminar & Visiting Speaker Series

*Tuesday, October 13th, 2015 - 3pm

TOMOAKI SHIRAO Professor and Chairman, Graduate School of Medicine Gunma University, Japan

TOPIC: Novel actin-dependent mechanism of synaptic plasticity.

Location: *Theatre C, Basic Med. Sci. Bldg.

RECENT PUBLICATIONS:

Yamazaki H, Kojima N, Kato K, Hirose H, Iwasaki T, Mizui T, Takahashi H, Hanamura K, Roppongi RT, Koibuchi N, Sekino Y, Mori N, Shirao T. "Spikar, a novel drebrin-binding protein, regulates the formation and stabilization of dendritic spines." J Neurochem. 128: 507-522 (2014)

Mizui T, Sekino Y, Yamazaki1, Yuta Ishizuka H, Takahashi H, Kojima N, Kojima M and ShiraoT. "Myosin II ATPase activity mediates the long-term potentiation-induced exodus of stable F-actin bound by drebrin A from dendritic spines" PLoS One. 9(1):e85367. (2014)

Tanabe K, Yamazaki H, Inaguma Y, Asada A, Kimura T, Takahashi J, Taoka M, Ohshima T, Furuichi T, Isobe T, Nagata K, Shirao T, Hisanaga S. "Phosphorylation of drebrin by cyclin-dependent kinase 5 and its role in neuronal migration." PLoS One. 9:e92291 (2014)

Yuta Ishizuka, Hideo Shimizu, Eiko Takagi, Mai Kato, Hirotaka Yamagata, Masahiko Mikuni, Tomoaki Shirao. "Histone deacetylase mediates the decrease in drebrin cluster density induced by amyloid beta oligomers" Neurochem. Int. 76:114-121 (2014)

Kudo S, Suzuki Y, Noda S, Mizui T, Shirai K, Okamoto M, Kaminuma T, Yoshida Y, Shirao T and Nakano T. "Comparison of the radiosensitivities of neurons and glial cells derived from the same rat brain." Exp. Ther. Med. 8: 754-758, 2014

POSITIONS/EMPLOYMENT:

1984 Research Associate at the Dept of Pharmacology, Gunma University School of Medicine 1988 Research Associate at the Laboratory of Neurochemistry, Natl Inst for Physiol Sci 1991 Associate Professor at the Department of Physiology, Keio University School of Medicine 1993-present - Professor, Dept of Neurobiol and Behavior, Gunma Univ Sch of Med, 2001-2006 Director, Inst of Exp Animal Res, Gunma Univ Sch of Med, Maebashi, Japan 2004-present Vice-chairman, ERSC, Gunma Univ Grad Sch of Med

Partners: Winnipeg Chapter Society for Neuroscience St. Boniface Hospital Research Centre, Division of Neurodegenerative Disorders Neuroscience Research Program, Health Sciences Centre & University of Manitoba

For more information, contact the MNN Office at (T) 235.3939 or email: mnn@sbrc.ca

Kelly Jorundson Winnipeg Chapter Society for Neuroscience R4046 - 351 Tache Avenue Winnipeg, MB R2H 2A6

Tel: 204.235.3939 Fax: 204.237.4092 Email: kjorund@sbrc.ca OR kjorund@yahoo.ca

Website: www.sfn-manitoba.ca

Kelly Jorundson Administrative Manager Division of Neurodegenerative Disorders St. Boniface Hospital Research

& Department of Pharmacology & Therapeutics College of Medicine, Faculty of Health Sciences University of Manitoba Room R4046 - 351 Taché Avenue Winnipeg, MB R2H 2A6 CANADA

Tel: 204.235.3939 | Fax: 204.237.4092 Email: kjorund@sbrc.ca OR Kelly.Jorundson@umanitoba.ca Website: www.sbrc.ca/dnd OR www.umanitoba.ca/medicine/units/pharmacology